Description
Parkinson et parkinsonismes
- Machine learning for early detection and severity classification in people with Parkinson's disease
Sci Rep. 2025 Jan 2;15(1):234. doi: 10.1038/s41598-024-83975-3.ABSTRACTEarly detection of Parkinson's disease (PD) and accurate assessment of disease progression are critical for optimizing treatment […]
- Gait-based Parkinson's disease diagnosis and severity classification using force sensors and machine learning
Sci Rep. 2025 Jan 2;15(1):328. doi: 10.1038/s41598-024-83357-9.ABSTRACTA dual-stage model for classifying Parkinson's disease severity, through a detailed analysis of Gait signals using force sensors […]
- Diagnosis and treatment of autonomic failure, pain and sleep disturbances in Parkinson's disease: guideline "Parkinson's disease" of the German Society of Neurology
J Neurol. 2025 Jan 3;272(1):90. doi: 10.1007/s00415-024-12730-5.ABSTRACTBACKGROUND AND OBJECTIVE: Non-motor symptoms frequently develop throughout the disease course of Parkinson's disease (PD), and […]
- Neuroinflammation as a Link in Parkinson's and Alzheimer's Diseases: A Systematic Review and Meta-Analysis
Aging Dis. 2024 Dec 18. doi: 10.14336/AD.2024.1174. Online ahead of print.ABSTRACTNeuroinflammation plays a critical role in Alzheimer's (AD) and Parkinson's diseases (PD) onset, pathophysiology, and […]
- Current trends in blood biomarkers detection and neuroimaging for Parkinson's disease
Ageing Res Rev. 2025 Jan 8:102658. doi: 10.1016/j.arr.2025.102658. Online ahead of print.ABSTRACTParkinson's disease (PD) is a neurodegenerative disorder characterized by both motor and cognitive […]
- Automated analysis of spoken language differentiates multiple system atrophy from Parkinson's disease
J Neurol. 2025 Jan 15;272(2):113. doi: 10.1007/s00415-024-12828-w.ABSTRACTBACKGROUND AND OBJECTIVES: Patients with synucleinopathies such as multiple system atrophy (MSA) and Parkinson's disease (PD) […]
- Cognitive decline profiles associated with lewy pathology in the context of Alzheimer's disease neuropathologic change
Alzheimers Res Ther. 2024 Dec 20;16(1):270. doi: 10.1186/s13195-024-01628-z.ABSTRACTBACKGROUND: Alzheimer's disease neuropathologic change (ADNC) and Lewy pathology (LP) often coexist in cognitively […]
- Striatal-cortical dysconnectivity underlies somatosensory deficits in Parkinson's disease: Insights from rhythmic auditory-motor training
Neurobiol Dis. 2024 Dec 22:106778. doi: 10.1016/j.nbd.2024.106778. Online ahead of print.ABSTRACTEvidence indicates that neurodegenerative diseases spread through distinct brain networks. For […]
- Use of Transcranial Magnetic Stimulation to Probe Neuroplasticity and Predict Gait Performance After Treadmill Training in Parkinson's Disease
Mov Disord. 2024 Dec 31. doi: 10.1002/mds.30100. Online ahead of print.ABSTRACTBACKGROUND: Reduced step length is a hallmark of gait disturbance in people with Parkinson's disease (PD). Although […]
- Longitudinal network changes and phenoconversion risk in isolated REM sleep behavior disorder
Nat Commun. 2024 Dec 30;15(1):10797. doi: 10.1038/s41467-024-54695-z.ABSTRACTIsolated rapid eye movement sleep behavior disorder is a prodrome of α-synucleinopathies. Using positron emission […]
Traitements pharmacologiques
Médicaments
- Longitudinal Serotonergic and Dopaminergic Binding: Impact on Parkinson's Disease Progression and Levodopa Dyskinesia
J Neuroimaging. 2025 Jan-Feb;35(1):e70014. doi: 10.1111/jon.70014.ABSTRACTBACKGROUND AND PURPOSE: We investigated the relationship between serotonergic and dopaminergic specific binding transporter […]
- Co-Expression of Tardive Dyskinesia and Drug-Induced Parkinsonism in Rats Chronically Treated With Haloperidol
Neuropsychopharmacol Rep. 2025 Mar;45(1):e12524. doi: 10.1002/npr2.12524.ABSTRACTAIM: We aimed to create a rat model of drug-induced parkinsonism and tardive dyskinesia by chronic administration of […]
- Predicting Parkinson's Disease Using a Deep-Learning Algorithm to Analyze Prodromal Medical and Prescription Data
J Clin Neurol. 2025 Jan;21(1):21-30. doi: 10.3988/jcn.2024.0175.ABSTRACTBACKGROUND AND PURPOSE: Parkinson's disease (PD) is characterized by various prodromal symptoms, and these symptoms are mostly […]
- Ginsenosides Rg1, Rb1 and rare ginsenosides: Promising candidate agents for Parkinson's disease and Alzheimer's disease and network pharmacology analysis
Pharmacol Res. 2025 Jan 3;212:107578. doi: 10.1016/j.phrs.2025.107578. Online ahead of print.ABSTRACTGinseng has been commonly used as a traditional Chinese medicine in Asian countries for thousands […]
- The effect of L-dopa and DBS on cortical oscillations in Parkinson's disease analyzed by hidden Markov model algorithm
Neuroimage. 2025 Jan;305:120992. doi: 10.1016/j.neuroimage.2024.120992. Epub 2024 Dec 30.ABSTRACTBACKGROUND: Parkinson's disease (PD) is a movement disorder caused by dopaminergic neurodegeneration. […]
Études cliniques phase 3 et phase 4
- Clinical Trial Highlights: Anti-Inflammatory and Immunomodulatory Agents
J Parkinsons Dis. 2024 Sep 26. doi: 10.3233/JPD-240353. Online ahead of print.ABSTRACT Inflammation and immune dysregulation have been linked to the pathogenesis and progression of Parkinson's […]
- Rett Syndrome: The Emerging Landscape of Treatment Strategies
CNS Drugs. 2024 Sep 9. doi: 10.1007/s40263-024-01106-y. Online ahead of print.ABSTRACTRett syndrome (RTT) has enjoyed remarkable progress in achieving specific therapies. RTT, a unique […]
- Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials
J Parkinsons Dis. 2024;14(6):1243-1255. doi: 10.3233/JPD-240035.ABSTRACTBACKGROUND: DATATOP was a study of early Parkinson's disease (PD) conducted in the 1980 s, before mandatory folic acid […]
- Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2024 Update
J Parkinsons Dis. 2024 Jul 18. doi: 10.3233/JPD-240272. Online ahead of print.ABSTRACTBACKGROUND: For the past five years, our annual reports have been tracking the clinical development of new […]
- Continuous Subcutaneous Foslevodopa-Foscarbidopa in Parkinson's Disease: A Mini-Review of Current Scope and Future Outlook
Mov Disord Clin Pract. 2024 Jul 11. doi: 10.1002/mdc3.14161. Online ahead of print.ABSTRACTBACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and […]
Traitements non pharmacologiques
Chirurgie
- Unveiling the efficacy of repetitive transcranial magnetic stimulation in Parkinson's disease: A comprehensive review of systematic analyses
PLoS One. 2025 Jan 6;20(1):e0313420. doi: 10.1371/journal.pone.0313420. eCollection 2025.ABSTRACTBACKGROUND: Many systematic reviews (SRs) have reported the repetitive transcranial magnetic […]
- Repetitive transcranial magnetic stimulation improves cognition, depression, and walking ability in patients with Parkinson's disease: a meta-analysis
BMC Neurol. 2024 Dec 24;24(1):490. doi: 10.1186/s12883-024-03990-9.ABSTRACTOBJECTIVE: To evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) on cognitive function, […]
- Altered Cognitive Networks Connectivity in Parkinson's Disease During the Microlesion Period After Deep Brain Stimulation
CNS Neurosci Ther. 2024 Dec;30(12):e70184. doi: 10.1111/cns.70184.ABSTRACTAIMS: Cognitive functions are reduced in Parkinson's disease (PD) patients after deep brain stimulation (DBS) surgery. […]
- Non-conventional deep brain stimulation in a network model of movement disorders
Biomed Phys Eng Express. 2024 Dec 20;11(1). doi: 10.1088/2057-1976/ad9c7d.ABSTRACTConventional deep brain stimulation (DBS) for movement disorders is a well-established clinical treatment. Over the […]
- Current and future applications of local field potential-guided programming for Parkinson's disease with the Percept rechargeable neurostimulator
Neurodegener Dis Manag. 2024;14(5):131-147. doi: 10.1080/17582024.2024.2404386. Epub 2024 Sep 30.ABSTRACTDeep brain stimulation (DBS) has been established as an effective neuromodulatory treatment […]
Approches multidisciplinaires
- Gait ecological assessment in persons with Parkinson's disease engaged in a synchronized musical rehabilitation program
NPJ Parkinsons Dis. 2025 Jan 7;11(1):12. doi: 10.1038/s41531-024-00852-6.ABSTRACTData on gait parameters during real-life activities and home rehabilitation programs for Persons with Parkinson's […]
- Interpersonal Psychotherapy for the Treatment of Depression in Parkinson's Disease: Results of a Randomized Controlled Trial
Mov Disord. 2024 Nov 20. doi: 10.1002/mds.30061. Online ahead of print.ABSTRACTBACKGROUND: Depression is a common nonmotor complication in Parkinson's disease (PD). However, few studies have […]
- Optimizing rehabilitation strategies in Parkinson's disease: a comparison of dual cognitive-walking treadmill training and single treadmill training
Sci Rep. 2024 Oct 24;14(1):25210. doi: 10.1038/s41598-024-75422-0.ABSTRACTDual cognitive-walking treadmill training (DTT), designed to replicate real-life walking conditions, has shown promise effect […]
- Implication of nutrition in severity of symptoms and treatments in quality of life in Parkinson's disease: a systematic review
Front Nutr. 2024 Oct 8;11:1434290. doi: 10.3389/fnut.2024.1434290. eCollection 2024.ABSTRACTParkinson's disease (PD) is characterized by motor and non-motor symptoms. Nutritional alterations are one […]
- Enhancing quality of life in Parkinson's disease: The crucial role of multidisciplinary approaches and innovative psychiatric treatments
J Neurol Sci. 2024 Oct 21;466:123284. doi: 10.1016/j.jns.2024.123284. Online ahead of print.NO ABSTRACTPMID:39461319 | DOI:10.1016/j.jns.2024.123284
Thérapies alternatives
- Effects of aerobic and resistance training on walking and balance abilities in older adults with Parkinson's disease: A systematic review and meta-analysis
PLoS One. 2025 Jan 9;20(1):e0314539. doi: 10.1371/journal.pone.0314539. eCollection 2025.ABSTRACTOBJECTIVE: To explore the impact of aerobic and resistance training on walking and balance abilities […]
- Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study
JMIR Aging. 2025 Jan 14;8:e62930. doi: 10.2196/62930.ABSTRACTBACKGROUND: Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms. Recently, dance has […]
- Quality assessment and umbrella review of systematic reviews about dance for people with Parkinson's disease
PLoS One. 2024 Dec 31;19(12):e0311003. doi: 10.1371/journal.pone.0311003. eCollection 2024.ABSTRACTOBJECTIVE(S): To determine (1) the quality of systematic reviews about dance-based intervention in […]
- Rock Steady Boxing: A qualitative evaluation of a community exercise program for people with Parkinson's disease
PLoS One. 2024 Dec 19;19(12):e0309522. doi: 10.1371/journal.pone.0309522. eCollection 2024.ABSTRACTPURPOSE: Regular exercise can reduce the symptoms of Parkinson's disease, a common neurodegenerative […]
- Therapeutic singing and expiratory muscle strength training in Parkinson's disease: a mixed methods comparison
Front Rehabil Sci. 2024 Nov 21;5:1478490. doi: 10.3389/fresc.2024.1478490. eCollection 2024.ABSTRACTINTRODUCTION: The purpose of this study was to understand how two respiratory strengthening […]
Qualité de vie des patients
Expérience patient
- Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis
Am J Chin Med. 2024 Dec 24:2450086. doi: 10.1142/S0192415X24500861. Online ahead of print.ABSTRACTParkinson's disease (PD) is a progressive neurodegenerative disorder without a definitive cure. […]
- Prevalence and associated risk factors of post COVID fatigue among Parkinson's disease patients during one year follow up
Sci Rep. 2024 Dec 30;14(1):31966. doi: 10.1038/s41598-024-83567-1.ABSTRACTOne of the most common post-COVID-19 condition is persistent fatigue, while post-COVID fatigue among Parkinson's disease (PD) […]
- Multi-contextual Factors that Influence Work-Life Balance of Family Caregivers of Adults with Parkinson's Disease
J Occup Environ Med. 2024 Nov 19. doi: 10.1097/JOM.0000000000003283. Online ahead of print.ABSTRACTOBJECTIVE: The purpose of study was to explore family caregiver perspectives on work-life balance […]
- A qualitative study exploring the clinical phenomenology and impact of hypersexuality in patients with Parkinson's Disease
Sci Rep. 2024 Nov 20;14(1):28697. doi: 10.1038/s41598-024-79966-z.ABSTRACTHypersexuality (HS) is a complex yet underreported phenomenon in Parkinson's disease (PD), profoundly impacting patients' […]
- The impact of Dance for Parkinson's Disease on subjective well-being and functioning as experienced by dancers and their relatives - A descriptive study
J Bodyw Mov Ther. 2024 Oct;40:520-524. doi: 10.1016/j.jbmt.2024.04.059. Epub 2024 May 6.ABSTRACTINTRODUCTION: Research has described improved health for persons with Parkinson's Disease (PD) who […]
Technologies de soutien
- Evaluating gait and postural responses to subthalamic stimulation and levodopa: A prospective study using wearable technology
Eur J Neurol. 2025 Jan;32(1):e16580. doi: 10.1111/ene.16580.ABSTRACTBACKGROUND: The efficacy of subthalamic stimulation on axial signs of Parkinson's disease (PD) is debated in the literature. This […]
- Wearable devices may aid the recognition of fluctuation-related pain in Parkinson's disease-An exploratory, cross-sectional analysis of two prospective observational studies
PLoS One. 2025 Jan 14;20(1):e0316563. doi: 10.1371/journal.pone.0316563. eCollection 2025.ABSTRACTFluctuation-related pain (FRP) affects more than one third of people with Parkinson's disease (PwP, […]
- Promoting Physical Activity in People With Parkinson's Disease Through a Smartphone App: A Pilot Study
J Neurol Phys Ther. 2025 Jan 7. doi: 10.1097/NPT.0000000000000507. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Physical activity has beneficial symptomatic effects for people with […]
- Satisfaction, effectiveness, and usability of telerehabilitation for Parkinson's disease patients
J Rehabil Med. 2025 Jan 3;57:jrm39819. doi: 10.2340/jrm.v57.39819.ABSTRACTOBJECTIVE: To evaluate the satisfaction, effectiveness, and usability of a telerehabilitation programme for Parkinson's […]
- The feasibility of a visuo-cognitive training intervention using a mobile application and exercise with stroboscopic glasses in Parkinson's: Findings from a pilot randomised controlled trial
PLOS Digit Health. 2024 Dec 18;3(12):e0000696. doi: 10.1371/journal.pdig.0000696. eCollection 2024 Dec.ABSTRACTBACKGROUND: There is currently no pharmacological treatment for visuo-cognitive […]
Associations et ordres professionnels
Québec
- 🧪 Participez à la recherche sur la maladie de Parkinson !on 17 janvier 2025
🧪 Participez à la recherche sur la maladie de Parkinson ! 💪 L’Université Concordia recrute des participants atteints de la maladie de Parkinson pour deux projets de recherche novateurs […]
- Découvrez les travaux du Dr Edward Fon sur la maladie de Parkinson !on 17 janvier 2025
✨ Découvrez les travaux du Dr Edward Fon, un pionnier de la recherche sur la maladie de Parkinson ! ✨ 👉 Faire un don : https://tinyurl.com/offrez-lespoir Dans cette vidéo, Dr Edward Fon, […]
- 📢 GBA1 Meeting 2025 à Montréal !on 17 janvier 2025
📢 GBA1 Meeting 2025 à Montréal ! 🧬 Nous sommes ravis d'annoncer que le GBA1 Meeting 2025 se tiendra du 5 au 7 juin 2025 à l'Hôtel Delta Montréal. Cet événement international […]
- En quête de Dopamine - Baladoon 17 janvier 2025
Parkinson Québec présente : "En Quête de Dopamine" 🧡 ✨Nous sommes ravis de dévoiler notre tout nouveau balado audio-visuel et bilingue : "En Quête de Dopamine". Ce projet audacieux et […]
- Pour Manon Day, chaque mot prononcé est un acte de courageon 6 Décembre 2024
Pour Manon Day, chaque mot prononcé est un acte de courage. Découvrez comment elle surmonte son trouble de la parole et ses conseils pour mieux communiquer avec ceux qui vivent des défis […]
Canada
- Experimental Drugs ORCHESTRA and PADOVA show Mixed Resultson 17 janvier 2025
Parkinson’s is characterized by the accumulation of misfolded alpha-synuclein proteins in the brain. These proteins are a key factor in the development of Parkinson’s, as they clump together and […]
- No Nightmares Before Christmas: How to Manage Your Holiday Stresson 6 Décembre 2024
By: Kateryna Voznyuk […]
- Bridging the Gap: The Powerful Role of Intergenerational Conversationson 6 Décembre 2024
-Irene ChenMeaningful human connection is one of the most powerful buffers against life’s challenges and uncertainties. Among the most transformative types of connections are intergenerational.The […]
- Parkinson’s and possibilities: key findings from the 3rd Annual Canadian Movement Disorders Meetingon 27 novembre 2024
On Nov. 8–9, researchers, physicians, movement disorder specialists and healthcare professionals convened in Toronto for the 3rd Annual Canadian Movement Disorders Meeting. Their goal, to share the […]
- Les points clés de notre atelier sur l’engagement des patients à Montréalon 27 novembre 2024
Le 24 juillet, l’équipe de recherche de Parkinson Canada a organisé un atelier sur l’engagement des patients dans la recherche sur la maladie de Parkinson à Montréal. Dans le cadre de sa […]
États-Unis
- Dancing shown to ease depression in Parkinson’s diseaseon 17 janvier 2025
- Blood pressure treatment eases Parkinson’s tremor in small trialon 17 janvier 2025
- Effort will automate ANPD001 cell therapy production for Parkinson’son 17 janvier 2025
- Levodopa helps to ease muscle stiffness during faster movementon 17 janvier 2025
- Hearing loss may be early warning sign for Parkinson’s disease: Studyon 17 janvier 2025
- Creativity in People with Parkinson’s Diseaseon 17 janvier 2025
- Register Today -- Parkinson's Symposium with The Michael J. Fox Foundationon 17 janvier 2025
- Your Top Questions on Parkinson’s and Exercise Answered (Ask the MD Podcast)on 17 janvier 2025
- Sleeping with head elevated eases morning dizziness in patient, 69on 27 novembre 2024
- Study on skin test to detect alpha-synuclein in Parkinson’s wins granton 27 novembre 2024
International
- L’activité physique pour vaincre la fatigue liée à Parkinson !on 17 janvier 2025
L’activité physique pour vaincre la fatigue liée à Parkinson ! La fatigue fait partie des symptômes non-moteurs les plus fréquents de la maladie de Parkinson. Invisible […]
- Podcast: understanding Deep Brain Stimulation and Parkinson’son 6 Décembre 2024
“Deep Brain Stimulation (DBS surgery) doesn’t cure Parkinson’s, but it helps a lot,” says Gerlach Roomans, guest speaker on the latest episode of our Parkinson’s Life podcast. In this […]
- TwinBrain: what new ‘brain in motion’ technology can reveal about Parkinson’son 6 Décembre 2024
Neuroimaging has made huge strides in trying to demystify the human brain, but there’s still so much to discover. While most studies have been conducted under stationary conditions – usually with […]
- Parkinson’s and women: new global initiative to explore unique impacton 27 novembre 2024
Non-profit Critical Path Institute (C-Path) plans to focus on a long-overlooked area of research – the different ways Parkinson’s uniquely affects women and individuals across the sex and gender […]
- Le tennis de table : une discipline bénéfique pour les personnes atteintes de Parkinsonon 27 novembre 2024
Le tennis de table : une discipline bénéfique pour les personnes atteintes de Parkinson Accueil > Actualités > Le tennis […]
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