Description
Parkinson et parkinsonismes
- Clinical Insight on "Association Between Stress Hyperglycemia Ratio and Parkinson's Disease Across Different Glucose Metabolism Statuses-A Prospective Study From UK Biobank"
Eur J Neurol. 2025 Aug;32(8):e70340. doi: 10.1111/ene.70340.NO ABSTRACTPMID:40838419 | DOI:10.1111/ene.70340
- Early functional changes in lewy body dementia: roles of dynamics, locus coeruleus, and compensation
Alzheimers Res Ther. 2025 Aug 23;17(1):199. doi: 10.1186/s13195-025-01828-1.ABSTRACTDementia with Lewy bodies (DLB) is marked by multidomain cognitive impairments, with fluctuations in cognition and […]
- Neural Basis of Anxiety in Dementia With Lewy Bodies
Int J Geriatr Psychiatry. 2025 Sep;40(9):e70150. doi: 10.1002/gps.70150.ABSTRACTOBJECTIVE: The association between core clinical features and anxiety and the neural basis of anxiety in patients with […]
- From resting-state to movement: The role of cortical networks in parkinsonian gait
Gait Posture. 2025 Aug 28:S0966-6362(25)00680-0. doi: 10.1016/j.gaitpost.2025.08.079. Online ahead of print.ABSTRACTBACKGROUND: Gait impairments in Parkinson's disease (PD) arise from disruptions in […]
- Quality of life measures in Parkinson's disease: a systematic literature review of patient-reported outcomes measures (PROMs) and their psychometric properties
J Neurol. 2025 Aug 28;272(9):598. doi: 10.1007/s00415-025-13348-x.ABSTRACTBACKGROUND: Quality-of-life (QoL) measures are key for monitoring health of patients with Parkinson's disease (PD).OBJECTIVE: […]
- Stress Hyperglycemia Ratio as a Predictor of Parkinson's Disease: Statistical Caveats Matter
Eur J Neurol. 2025 Aug;32(8):e70333. doi: 10.1111/ene.70333.NO ABSTRACTPMID:40827593 | DOI:10.1111/ene.70333
- Acoustic prominence production in Parkinson's disease when there is a shared communicative goal
J Acoust Soc Am. 2025 Aug 1;158(2):1508-1525. doi: 10.1121/10.0039048.ABSTRACTThis study quantified the acoustic characteristics of prominence in people with Parkinson's disease (PD) when engaging in […]
- Do we need drugs for psychiatric symptoms specifically for Parkinson's disease?
J Parkinsons Dis. 2025 Aug 21:1877718X251370970. doi: 10.1177/1877718X251370970. Online ahead of print.ABSTRACTAlthough the need for better medications for the treatment of psychiatric symptoms in […]
- Motor features that distinguish isolated REM sleep behavior disorder patients from healthy controls: A systematic review
J Parkinsons Dis. 2025 Sep 1:1877718X251359225. doi: 10.1177/1877718X251359225. Online ahead of print.ABSTRACTIndividuals with isolated REM sleep behavior disorder (iRBD) are at high risk of […]
- Patients with small fiber neuropathy exhibit more pronounced non-motor symptoms in Parkinson's disease
J Parkinsons Dis. 2025 Sep 2:1877718X251371538. doi: 10.1177/1877718X251371538. Online ahead of print.ABSTRACTBackgroundPeripheral neuropathy in Parkinson's disease (PD) may not be an isolated […]
Traitements pharmacologiques
Médicaments
- Pathophysiology and pharmacological management for sleep problems in Parkinson's disease
J Parkinsons Dis. 2025 Sep 2:1877718X251371945. doi: 10.1177/1877718X251371945. Online ahead of print.ABSTRACTSleep problems are among the most frequently reported non-motor symptoms of Parkinson's […]
- Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Parkinson's Disease: Real-World Short-Term Data on Tolerability, Infusion Rate Adjustments and Concomitant Medication
Mov Disord Clin Pract. 2025 Jul 28. doi: 10.1002/mdc3.70249. Online ahead of print.ABSTRACTBACKGROUND: Foslevodopa/foscarbidopa (LDp/CDp) significantly reduced motor fluctuations in people with […]
- What medicines do people with Parkinson's disease want?
J Parkinsons Dis. 2025 Aug 26:1877718X251366032. doi: 10.1177/1877718X251366032. Online ahead of print.ABSTRACTParkinson's disease (PD) is a heterogeneous condition that presents variable clinical, […]
- Sex differences in the pharmacokinetics of levodopa and carbidopa in patients with Parkinson's disease
Parkinsonism Relat Disord. 2025 Aug 19;139:108006. doi: 10.1016/j.parkreldis.2025.108006. Online ahead of print.ABSTRACTINTRODUCTION: Levodopa pharmacokinetics exhibit substantial interindividual […]
- Potentially Inappropriate Medication Use in Patients With Parkinson's Disease: Analysis of Korean National Health Insurance Claims Data
J Clin Neurol. 2025 Sep;21(5):405-414. doi: 10.3988/jcn.2025.0122.ABSTRACTBACKGROUND AND PURPOSE: Polypharmacy is common in Parkinson's disease (PD). This includes appropriate medications for […]
Études cliniques phase 3 et phase 4
- Advances in Neurodegenerative Disease Therapy: Stem Cell Clinical Trials and Promise of Engineered Exosomes
CNS Neurosci Ther. 2025 Sep;31(9):e70577. doi: 10.1111/cns.70577.ABSTRACTAIM: This review provides a systematic evaluation of 94 stem cell clinical trials to treat neurodegenerative diseases, […]
- Cognitive outcomes of deep brain stimulation depend on age and hippocampal connectivity in Parkinson's and Alzheimer's disease
Alzheimers Dement. 2025 Aug;21(8):e70498. doi: 10.1002/alz.70498.ABSTRACTINTRODUCTION: Here we contrast cognitive outcomes of deep brain stimulation (DBS) in Parkinson's disease (PD) with Alzheimer's […]
- Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study
Neurotherapeutics. 2025 Jul 31:e00690. doi: 10.1016/j.neurot.2025.e00690. Online ahead of print.ABSTRACTParkinson's disease (PD) is a neurodegenerative movement disorder of high global burden. […]
- How to dose extended-release carbidopa-levodopa capsules (IPX203, CREXONT) in patients with Parkinson's disease
Clin Park Relat Disord. 2025 Jun 18;13:100357. doi: 10.1016/j.prdoa.2025.100357. eCollection 2025.ABSTRACTIPX203 (CREXONT®) is a novel, oral, extended-release (ER) carbidopa-levodopa (CD-LD) […]
- Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan
Mov Disord Clin Pract. 2025 Aug 7. doi: 10.1002/mdc3.70259. Online ahead of print.ABSTRACTBACKGROUND: Sialorrhea, caused by various neurological diseases, impairs patient health and quality of life. […]
Traitements non pharmacologiques
Chirurgie
- One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders
Mov Disord Clin Pract. 2025 Aug 14. doi: 10.1002/mdc3.70274. Online ahead of print.ABSTRACTBACKGROUND: Deep brain stimulation (DBS) is an established treatment for movement disorders such as […]
- From subthalamic local field potentials to the selection of chronic deep brain stimulation contacts in Parkinson's disease - A systematic review
Brain Stimul. 2025 Aug 11;18(5):1499-1510. doi: 10.1016/j.brs.2025.08.004. Online ahead of print.ABSTRACTBACKGROUND: Programming deep brain stimulation (DBS) of the subthalamic nucleus for optimal […]
- From adaptive deep brain stimulation to adaptive circuit targeting
Nat Rev Neurol. 2025 Sep 3. doi: 10.1038/s41582-025-01131-5. Online ahead of print.ABSTRACTDeep brain stimulation (DBS) substantially improves motor symptoms and quality of life in people with […]
- Travel distance may have a negative impact on the outcome of deep brain stimulation in Parkinson's disease
Sci Rep. 2025 Aug 16;15(1):29992. doi: 10.1038/s41598-025-14519-6.ABSTRACTPotential beneficial effects of teleprogramming on the efficacy of deep brain stimulation (DBS) have not been studied. We […]
- Ethnic and Gender Disparities in Access to Deep Brain Stimulation Surgery for Parkinson's Disease
Mov Disord Clin Pract. 2025 Sep 3. doi: 10.1002/mdc3.70312. Online ahead of print.ABSTRACTBACKGROUND: Deep brain stimulation (DBS) is an established treatment for Parkinson's disease (PD) in […]
Approches multidisciplinaires
- An Interdisciplinary Approach to Assistive Technology for Parkinson's Disease Dementia
Clin Interv Aging. 2025 Aug 15;20:1253-1265. doi: 10.2147/CIA.S516786. eCollection 2025.ABSTRACTParkinson's Disease Dementia (PDD) and Parkinson's Disease-Mild Cognitive Impairment (PD-MCI) are […]
- Multidisciplinary inpatient care for Parkinson's disease: a single-centre cohort study on improvements in gait, overall motor function, and quality of life
Neurol Res Pract. 2025 Sep 2;7(1):62. doi: 10.1186/s42466-025-00422-y.ABSTRACTBACKGROUND: Parkinson's disease (PD) multimodal complex treatment (PD-MCT) is an inpatient therapeutic programme […]
- Effects of exercise modality-dose combinations on cognitive function in Parkinson's Disease: A bayesian dose-response systematic review and meta-analysis
Arch Gerontol Geriatr. 2025 Aug 19;139:105996. doi: 10.1016/j.archger.2025.105996. Online ahead of print.ABSTRACTOBJECTIVE: This study aimed to identify the most effective exercise modalities and […]
- Epigenetic Modulation and Brain Function in Parkinson's Disease: The Role of Exercise Alone or Combined With Polyphenols
Food Sci Nutr. 2025 Jul 28;13(8):e70696. doi: 10.1002/fsn3.70696. eCollection 2025 Aug.ABSTRACTParkinson's disease (PD) is a complex, progressive neurodegenerative disorder that affects millions […]
- Effects of Square Stepping Exercise on Physical, Cognitive and Psychosocial Fitness in People with Parkinson's Disease
Psychiatr Q. 2025 Aug 13. doi: 10.1007/s11126-025-10197-9. Online ahead of print.ABSTRACTParkinson's disease (PD) is a progressive disease characterised by motor and non-motor symptoms that affect […]
Thérapies alternatives
- Impairment in the behavioral control of body sway, gaze shift, and mental workload in Parkinson's disease
Sci Rep. 2025 Aug 19;15(1):30354. doi: 10.1038/s41598-025-12878-8.ABSTRACTWe tested Parkinson's disease (PD)-related impairments in the relationship between gaze shifts, body sway and mental workload […]
- Physical exercise modulates plasma irisin levels in endurance athletes: Implications for Parkinson's disease
Neurobiol Dis. 2025 Aug 23:107065. doi: 10.1016/j.nbd.2025.107065. Online ahead of print.ABSTRACTPhysical exercise (PE) improves clinical outcomes in individuals with Parkinson's disease (PD) through […]
- Minimal clinically important difference and substantial clinical benefits for single- and dual-task timed up and go test following motor-cognitive training in Parkinson's disease
Age Ageing. 2025 Aug 29;54(9):afaf241. doi: 10.1093/ageing/afaf241.ABSTRACTOBJECTIVE: To establish substantial clinical benefits (SCB) and minimal clinically important differences (MCIDs) for both […]
- New perspectives on molecular mechanisms underlying exercise-induced benefits in Parkinson's disease
NPJ Parkinsons Dis. 2025 Aug 23;11(1):256. doi: 10.1038/s41531-025-01113-w.ABSTRACTExercise offers neuroprotective benefits in Parkinson's disease (PD) by enhancing neurotrophic factors (e.g., BDNF, […]
- A Case Report on Home-Based End-of-Life Care with Traditional Korean Medicine Acupuncture and Herbal Medicine for an Elderly Patient with Parkinson's Disease
J Palliat Med. 2025 Aug 20. doi: 10.1177/10966218251368491. Online ahead of print.ABSTRACTBackground: Managing multiple symptoms in home-based palliative care (HBPC) is challenging. Acupuncture and […]
Qualité de vie des patients
Expérience patient
- Exploration of strategies used to maintain health and well-being among working adults caring for adults with Parkinson's disease
Geriatr Nurs. 2025 Aug 20;66(Pt A):103578. doi: 10.1016/j.gerinurse.2025.103578. Online ahead of print.ABSTRACTAIMS: The aim of this study was to explore the strategies utilized by working adults to […]
- Midlife Physical Activity, Disease Symptoms, and Quality of Life in Parkinson's Disease: A Structural Equation Modeling Approach
J Phys Act Health. 2025 Sep 1:1-10. doi: 10.1123/jpah.2024-0583. Online ahead of print.ABSTRACTBACKGROUND: While higher levels of physical activity (PA) during midlife are associated with lower risk […]
- Buffering brain aging: education moderates language impairment in Parkinson's disease
Front Cell Neurosci. 2025 Aug 20;19:1606451. doi: 10.3389/fncel.2025.1606451. eCollection 2025.ABSTRACTBACKGROUND: Cognitive reserve (CR) refers to the discrepancy between brain pathology and […]
- Associations of digestive diseases exposure and lifestyle factors with Parkinson's disease
NPJ Parkinsons Dis. 2025 Aug 18;11(1):245. doi: 10.1038/s41531-025-01098-6.ABSTRACTEmerging evidence highlights the importance of gastrointestinal (GI) dysfunction in Parkinson's disease (PD). While […]
- Assessment of Health-Related Quality of Life in Parkinson's Disease: A Systematic Review
Cureus. 2025 Jul 16;17(7):e88061. doi: 10.7759/cureus.88061. eCollection 2025 Jul.ABSTRACTDifferent studies conducted on the effects of Parkinson's Disease (PD) on the health-related quality of life […]
Technologies de soutien
- The Views of Healthcare Professionals on iFall, a Smartphone Application for Falls Reporting in Parkinson's Disease: A Qualitative Study - PubMed
Figure 2. Themes and subthemes of the… Figure 2. Themes and subthemes of the study.
- Evaluating a digital mental health intervention for people with Parkinson's (PACT): acceptability and feasibility randomised controlled trial - PubMed
Objectives: We developed a web application (PACT app) based on Acceptance and Commitment Therapy to support mental health for people with Parkinson's. Here, we assess the app's acceptability and the […]
- Telehealth versus face-to-face delivery of speech language pathology services: A systematic review and meta-analysis - PubMed
BackgroundThere is an increasing demand for the provision of speech language pathology (SLP) services via telehealth. Therefore, we systematically reviewed randomized controlled trials comparing […]
- Assessing balance and walking of people with Parkinson's disease via telehealth - PubMed
Purpose: Investigate the reliability of balance and walking assessments undertaken remotely via telehealth in people with PD. Material and methods: Thirty people with mild-to-moderate PD and 15 […]
- Parkinson's disease medication adjustments based on wearable device information compared to other methods: randomized clinical trial
NPJ Parkinsons Dis. 2025 Aug 20;11(1):249. doi: 10.1038/s41531-025-00977-2.ABSTRACTParkinson's disease (PD) is characterized by motor fluctuations, with alternating periods of good ("ON") and poor […]
Associations et ordres professionnels
Québec
- 🎒 Appel à bénévoles – Trek Parkinson à Charlevoix !on 5 septembre 2025
🎒 Appel à bénévoles – Trek Parkinson à Charlevoix ! Du 24 au 28 septembre, Parkinson Québec organise un trek inoubliable à Charlevoix… et nous avons besoin de vous ! Nous sommes à […]
- 🔎 Appel à participation – Projet de recherche sur la maladie de Parkinsonon 5 septembre 2025
🔎 Appel à participation – Projet de recherche sur la maladie de Parkinson L’Université d’Ottawa recrute des participants pour une étude innovante : « eCONSULT+ : Téléconsultations […]
- Photos from Parkinson Québec's poston 5 septembre 2025
✨ Un record historique grâce à vous tous ! ✨ La 15ᵉ édition du Défi Vélo Parkinson Québec a été un immense succès : ensemble, nous avons récolté 380 000 $, un montant record qui […]
- Line Beaudet reçoit la Médaille du couronnement du roi Charles IIIon 22 août 2025
L’engagement remarquable et le dévouement durable envers la communauté Parkinson de Line Beaudet, chercheuse au Centre de recherche du CHUM, ont été soulignés à la fin avril par la remise […]
- Naviguer Ensemble – Module 8 : S’inspirer et inspireron 22 août 2025
Naviguer Ensemble – Module 8 : S’inspirer et inspirer Vous n’êtes jamais seul dans ce voyage. Chaque moment partagé, chaque expérience racontée, est une source de force pour d’autres […]
- 🎉 Un événement inspirant en soutien à Parkinson Québec !on 22 août 2025
🎉 Un événement inspirant en soutien à Parkinson Québec ! ⛳️ Nous sommes ravis de vous partager une belle initiative communautaire : le groupe Rise Up and Tee Off Golf tiendra son 5e […]
- 🏈 Cette année, les Alouettes de Montréal s’associent à Parkinson Québec pour soutenir la causeon 22 août 2025
🏈 Cette année, les Alouettes de Montréal s’associent à Parkinson Québec pour soutenir la cause. Si vous ne le saviez pas, vous bénéficiez de 15 % de rabais sur vos billets individuels […]
- 🙏 Un immense merci à la Fondation de la famille Morris et Rosalind Goodman, précieux partenaire du Défi Vélo Parkinson Québec !on 22 août 2025
🙏 Un immense merci à la Fondation de la famille Morris et Rosalind Goodman, précieux partenaire du Défi Vélo Parkinson Québec ! En soutenant notre événement, la Fondation de la famille […]
Canada
- The Science of Doing Nothing: How the Default Mode Network Helps You Rechargeon 5 septembre 2025
By David KuaAugust 15th is National Relaxation Day!Our ‘hustle culture’ often values productivity and accomplishments. While chasing goals and getting things done can feel rewarding, being in […]
- New! Your 10-week guide to navigating a new Parkinson's medicationon 14 août 2025
Starting a new medication? We're here to help. View this email in your browser Adjusting to a new Parkinson’s medication can feel […]
- Science News: Golf Course Pesticides & Parkinson's Riskon 14 août 2025
Drinking water contamination plays a role, too. … … […]
- You're Invited, Stem cell therapies for Parkinson's: updates on the clinical trial pipelineon 14 août 2025
Join our August webinar View this email in your browser August 20, 2025 2:00–3:00 PM ET Online (Zoom)Register Now Parkinson Canada […]
États-Unis
- Brain stem cell transplant patients may be able to take milder drugson 5 septembre 2025
- Device lets Parkinson’s patients track their own motor symptomson 5 septembre 2025
- AI-designed Parkinson’s therapy prepares to move to clinical trialson 5 septembre 2025
- Hemoglobin discovery may offer strategy for Parkinson’s treatmenton 5 septembre 2025
- New technology to help Parkinson’s patients makes me hopefulon 5 septembre 2025
- Overactive dopamine cells may drive Parkinson’s brain damageon 5 septembre 2025
- Researchers are investigating many options to treat Parkinson’s disease with stem cells, including reprogramming them to replace...on 5 septembre 2025
- New Webinar: Parkinson's Medications 101on 5 septembre 2025
- Brain Imaging for Parkinson’s Diseaseon 5 septembre 2025
- Advances in Parkinson’s Therapies: Five Key Areas to Watchon 22 août 2025
International
- 10 delicious recipes for people with Parkinson’son 5 septembre 2025
It is well known that a balanced, nutritious diet can have a hugely positive impact on people with Parkinson’s. For 10 years, Parkinson’s Life has shared a range of […]
- Cure Parkinson’s and Alzheimer’s Research UK announce new partnershipon 5 septembre 2025
Two leading neurodegenerative research charities in the United Kingdom, The Cure Parkinson’s Trust and Alzheimer’s Research UK, have launched a partnership to develop innovative new treatments […]
- ENTRETIEN. Parkinson – Comité 57on 12 août 2025
ENTRETIEN. Parkinson – Comité 57 ENTRETIEN. Parkinson : « Leur maladie semble se stabiliser », un essai clinique prometteur pour ralentir l’évolution des […]
- Study finds further links between impulse control disorder and dopamine agonist medicationon 10 juillet 2025
Even a low dose of a dopamine agonist medication could cause an impulse control disorder in some people with Parkinson’s, a Scandinavian multi-centre study, IPAPS (Impulse control disorder […]
- Ultraprocessed foods (UPF) linked to increased risk of Parkinson’s – but more research neededon 10 juillet 2025
Eating ultraprocessed foods (UPF) such as ketchup and soda has been linked to increased risk of developing Parkinson’s, according to new research published by the American Academy of Neurology’s […]
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