Maladies complexes

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COVID longue

maladies_complexes_covid_longue via biblio.chum on Inoreader

Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19
on 5 Décembre 2025
Nat Commun. 2025 Nov 26;16(1):10552. doi: 10.1038/s41467-025-65597-z.ABSTRACTAlthough brain alterations have been reported in post-acute sequelae of SARS-CoV-2 (PASC), their prevalence and […]
Post-COVID-19 condition patients' utilisation of healthcare resources after implementation of an integrated care unit
on 5 Décembre 2025
Cost Eff Resour Alloc. 2025 Dec 2. doi: 10.1186/s12962-025-00667-z. Online ahead of print.NO ABSTRACTPMID:41331825 | DOI:10.1186/s12962-025-00667-z
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
on 5 Décembre 2025
Lancet Infect Dis. 2025 Nov 7:S1473-3099(25)00665-6. doi: 10.1016/S1473-3099(25)00665-6. Online ahead of print.NO ABSTRACTPMID:41213281 | DOI:10.1016/S1473-3099(25)00665-6
Pursuing Reduction in Fatigue After COVID-19 via Exercise and Rehabilitation (PREFACER): a protocol for a randomised feasibility trial
on 5 Décembre 2025
BMJ Open. 2025 Nov 9;15(11):e102112. doi: 10.1136/bmjopen-2025-102112.ABSTRACTINTRODUCTION: Over 777 million COVID-19 infections have occurred globally, with data suggesting that 10%-20% of those […]
Resistance Exercise Therapy After COVID-19 Infection: A Randomized Clinical Trial
on 5 Décembre 2025
JAMA Netw Open. 2025 Nov 3;8(11):e2534304. doi: 10.1001/jamanetworkopen.2025.34304.ABSTRACTIMPORTANCE: Long COVID presents an unmet therapeutic need.OBJECTIVE: To determine the effects of a […]
Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial
on 5 Décembre 2025
JAMA Neurol. 2025 Nov 10. doi: 10.1001/jamaneurol.2025.4415. Online ahead of print.ABSTRACTIMPORTANCE: Treatment for cognitive dysfunction due to postacute sequelae of long COVID (ie, symptoms of […]
A systematic review and meta-analysis of the impact of vaccination on prevention of long COVID - Nature
on 5 Décembre 2025
A systematic review and meta-analysis of the impact of vaccination on prevention of long COVID Nature
What Can We Learn Four Years On? A Multi-Centre Service Evaluation Exploring Symptoms, Functional Impact, Recovery and Care Pathways in Long Covid
on 7 novembre 2025
Health Expect. 2025 Dec;28(6):e70435. doi: 10.1111/hex.70435.ABSTRACTBACKGROUND: Long Covid (LC) is associated with long-term health impacts that require ongoing support from healthcare services. We […]
Clinical and cost-effectiveness of diverse posthospitalisation pathways for COVID-19: a UK evaluation using the PHOSP-COVID cohort
on 7 novembre 2025
BMJ Open Respir Res. 2025 Oct 31;12(1):e003224. doi: 10.1136/bmjresp-2025-003224.ABSTRACTBACKGROUND: Long covid has emerged as a complex health condition for millions of people worldwide following […]
Long COVID Trial Explores Anti-Inflammatory Treatment
on 7 novembre 2025
JAMA. 2025 Oct 31. doi: 10.1001/jama.2025.17537. Online ahead of print.NO ABSTRACTPMID:41171293 | DOI:10.1001/jama.2025.17537
Physiotherapy interventions in post- and long-COVID-19: a scoping review of the literature up to February 2023
on 7 novembre 2025
BMC Health Serv Res. 2025 Oct 30;25(1):1425. doi: 10.1186/s12913-025-13631-7.NO ABSTRACTPMID:41168795 | DOI:10.1186/s12913-025-13631-7
Identifying Pediatric Long COVID: Comparing an EHR Algorithm to Manual Review
on 7 novembre 2025
Appl Clin Inform. 2025 Oct;16(5):1445-1456. doi: 10.1055/a-2702-1574. Epub 2025 Oct 24.ABSTRACTLong COVID, characterized by persistent or recurring symptoms post-COVID-19 infection, poses challenges […]
Children and young people with persistent post-COVID-19 condition over 24 months: a mixed-methods study
on 7 novembre 2025
BMJ Paediatr Open. 2025 Oct 21;9(1):e003634. doi: 10.1136/bmjpo-2025-003634.ABSTRACTPURPOSE: While most children and young people (CYP) recover from COVID-19, some develop 'post-COVID-19 condition' […]
Persistent pain and brain fog after COVID-19 infection in European adults aged 50 and over: a population-based longitudinal study
on 7 novembre 2025
BMC Infect Dis. 2025 Oct 21;25(1):1366. doi: 10.1186/s12879-025-11761-1.ABSTRACTBACKGROUND: Psychological distress has been identified as a risk factor for long COVID in individuals infected with […]
Applicability and adaptation of cognitive behavior therapy for long COVID neuropsychiatric symptoms: a review with insights from ME/CFS
on 7 novembre 2025
BMC Infect Dis. 2025 Oct 10;25(1):1275. doi: 10.1186/s12879-025-11754-0.NO ABSTRACTPMID:41073921 | DOI:10.1186/s12879-025-11754-0
Inflammatory predictors of Post-COVID fatigue
on 7 novembre 2025
Brain Behav Immun Health. 2025 Sep 17;49:101109. doi: 10.1016/j.bbih.2025.101109. eCollection 2025 Nov.ABSTRACTThe biological mechanisms underlying objective and subjective fatigue in post-COVID […]
Return to work with long COVID: a rapid review of support and challenges
on 7 novembre 2025
BMJ Open. 2025 Oct 7;15(10):e101698. doi: 10.1136/bmjopen-2025-101698.ABSTRACTOBJECTIVES: To explore existing evidence for the provision of support for return to work (RTW) in long COVID (LC) […]
Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study
on 6 octobre 2025
Lancet Infect Dis. 2025 Sep 30:S1473-3099(25)00476-1. doi: 10.1016/S1473-3099(25)00476-1. Online ahead of print.ABSTRACTBACKGROUND: Post-acute sequelae of SARS-CoV-2 infection (PASC) remain a major […]
Long COVID exhibition co-produced with community opens at the Museum of Vancouver - Simon Fraser University
on 6 octobre 2025
Long COVID exhibition co-produced with community opens at the Museum of Vancouver Simon Fraser University
La COVID fait vieillir les vaisseaux sanguins des femmes, selon une étude - Radio-Canada
on 6 octobre 2025
La COVID fait vieillir les vaisseaux sanguins des femmes, selon une étude Radio-Canada

COVID longue : lignes directrices canadiennes

Mise à jour du 17 juillet 2025

Mise à jour du 31 mars 2025

Mise à jour du 5 mars 2025

Maladie de Lyme

maladies_complexes_lyme via biblio.chum on Inoreader

Quantifying the Public Health Impact of Lyme Disease in Minnesota: A Simulation Analysis of Reported and Unreported Cases
on 5 Décembre 2025
J Health Econ Outcomes Res. 2025 Nov 20;12(2):221-228. doi: 10.36469/001c.146618. eCollection 2025.ABSTRACTBackground: Lyme disease, the most common vector-borne disease in Minnesota, is estimated to […]
Polyvalent mRNA vaccine targeting outer surface protein C affords multi-strain protection against Lyme disease
on 5 Décembre 2025
NPJ Vaccines. 2025 Dec 4. doi: 10.1038/s41541-025-01326-3. Online ahead of print.ABSTRACTThere is currently no Lyme disease (LD) vaccine available for use in humans. Outer surface protein C (OspC) of […]
Genetic landscape of Borrelia burgdorferi sensu stricto in Canada: a study of genetic diversity
on 5 Décembre 2025
Sci Rep. 2025 Nov 20;15(1):40954. doi: 10.1038/s41598-025-24758-2.ABSTRACTBorrelia burgdorferi sensu stricto (s.s.), the causative agent of Lyme disease in North America, exhibits considerable […]
Guidelines for Lyme borreliosis: post-treatment Lyme disease syndrome (PTLDS)
on 5 Décembre 2025
Infect Dis Now. 2025 Nov 26:105205. doi: 10.1016/j.idnow.2025.105205. Online ahead of print.ABSTRACTPersistent symptoms following appropriate treatment of confirmed Lyme borreliosis (LB) require a […]
Risk Factors for Lyme Disease in the General Population-A Survey of Adults and Caregivers in 28 States
on 5 Décembre 2025
Open Forum Infect Dis. 2025 Oct 21;12(11):ofaf658. doi: 10.1093/ofid/ofaf658. eCollection 2025 Nov.ABSTRACTBACKGROUND: There are an estimated 476 000 diagnosed and treated cases of Lyme disease (LD) […]
Guidelines for diagnosis and treatment in neurology - Lyme neuroborreliosis
on 7 novembre 2025
Ger Med Sci. 2025 Oct 9;23:Doc13. doi: 10.3205/000349. eCollection 2025.ABSTRACTLyme disease is the most common tick-borne infectious disease in Europe. Neurological manifestations occur in 3-15% of […]
Cutaneous Lyme borreliosis: Guideline of the German Dermatology Society
on 7 novembre 2025
Ger Med Sci. 2025 Oct 9;23:Doc12. doi: 10.3205/000348. eCollection 2025.ABSTRACTThe current S2k guideline "kutane Borreliose" has been updated in accordance with the methodological standards of the […]
Identification of potential biomarkers for Lyme disease using bioinformatics and machine learning
on 7 novembre 2025
Clin Exp Med. 2025 Oct 31;25(1):341. doi: 10.1007/s10238-025-01803-y.ABSTRACTLyme disease (LD) presents significant diagnostic challenges due to the absence of a reliable screening method for initial […]
The diagnostic potential of proteomics and machine learning in Lyme neuroborreliosis
on 7 novembre 2025
Nat Commun. 2025 Oct 27;16(1):9322. doi: 10.1038/s41467-025-64903-z.ABSTRACTLyme neuroborreliosis (LNB), a nervous system infection caused by tick-borne spirochetes of the Borrelia burgdorferi sensu […]
Late Lyme neuroborreliosis encephalomyelitis with distinct MRI features-a case report and systematic literature review
on 7 novembre 2025
J Neurol. 2025 Oct 26;272(11):729. doi: 10.1007/s00415-025-13475-5.ABSTRACTBACKGROUND: Central nervous system (CNS) Lyme neuroborreliosis (LNB) rarely occurs. Clinical and radiological findings are […]
Targeted volume imaging reveals early vascular interactions of Lyme disease pathogen in skin
on 7 novembre 2025
Nat Commun. 2025 Oct 22;16(1):9330. doi: 10.1038/s41467-025-64326-w.ABSTRACTAlthough the contours of the dissemination pathways of human pathogenic spirochetes in the vertebrate hosts are known, […]
Atypical facial oedema in acrodermatitis chronica atrophicans: A potential clue for early diagnosis in Lyme disease
on 7 novembre 2025
Clin Exp Dermatol. 2025 Oct 11:llaf450. doi: 10.1093/ced/llaf450. Online ahead of print.NO ABSTRACTPMID:41074274 | DOI:10.1093/ced/llaf450
The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease
on 7 novembre 2025
J Clin Microbiol. 2025 Oct 9:e0062925. doi: 10.1128/jcm.00629-25. Online ahead of print.ABSTRACTThere are nearly 500,000 cases of Lyme disease each year in the United States; 10%-20% of them result […]
Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 - PubMed
on 6 octobre 2025
Despite its importance in pathogenesis, the hematogenous dissemination pathway of B. burgdorferi is still largely uncharacterized. To probe the molecular details of transendothelial migration more […]
Excess Healthcare Costs and Resource Utilisation of Lyme Borreliosis in Germany: A Propensity Score-Matched Cohort Study - PubMed
on 6 octobre 2025
Aim: Lyme borreliosis (LB) is the most common tick-borne disease in Germany; however, data on the economic burden of LB are limited. In this study, we aim to report healthcare costs, healthcare […]
Identification of hub gene and immune infiltration in Lyme disease revealed by weighted gene co-expression network analysis and machine learning
on 6 octobre 2025
Eur J Med Res. 2025 Sep 26;30(1):860. doi: 10.1186/s40001-025-03108-y.ABSTRACTINTRODUCTION: Lyme disease (LD), caused by the spirochete Borrelia burgdorferi (Bb), is a multisystem disorder with early […]
Lyme borreliosis risk perceptions, disease knowledge, and training among at-risk groups
on 6 octobre 2025
BMC Public Health. 2025 Sep 30;25(1):3160. doi: 10.1186/s12889-025-23604-4.ABSTRACTBACKGROUND: Lyme borreliosis (LB) is the most common tick-borne disease in Europe. Although there are indicators […]
What Is Lyme Disease?
on 6 octobre 2025
JAMA. 2025 Aug 25. doi: 10.1001/jama.2025.13708. Online ahead of print.NO ABSTRACTPMID:40853565 | DOI:10.1001/jama.2025.13708
A novel single-tier serologic test to diagnose all stages of Lyme disease
on 6 octobre 2025
J Clin Microbiol. 2025 Aug 20:e0048325. doi: 10.1128/jcm.00483-25. Online ahead of print.ABSTRACTLyme disease, a bacterial zoonosis, is the most commonly reported vector-borne disease in the United […]
Cerebrospinal fluid protein profiling of inflammatory and neurobiological markers in Lyme neuroborreliosis
on 6 octobre 2025
Sci Rep. 2025 Jun 20;15(1):20190. doi: 10.1038/s41598-025-06146-y.ABSTRACTLyme neuroborreliosis (LNB) is the most common form of disseminated Lyme borreliosis in Europe and North America. There are […]

Encéphalomyélite myalgique

maladies_complexes_encephalomyelite via biblio.chum on Inoreader

Virus Genome Sequences in the Blood of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
on 5 Décembre 2025
medRxiv [Preprint]. 2025 Nov 7:2025.11.06.25339689. doi: 10.1101/2025.11.06.25339689.ABSTRACTMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a baffling disease. The disease has a wide […]
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
on 5 Décembre 2025
Cell Rep Med. 2025 Nov 18;6(11):102449. doi: 10.1016/j.xcrm.2025.102449. Epub 2025 Nov 7.ABSTRACTLong COVID (LC) manifests with sex-specific differences, particularly in those with myalgic […]
Contested and neglected: Social and medical marginalization in severe Chronic Fatigue Syndrome
on 5 Décembre 2025
Soc Sci Med. 2025 Nov 8;388:118766. doi: 10.1016/j.socscimed.2025.118766. Online ahead of print.ABSTRACTThis study addresses the persistent invisibility of people with severe Myalgic […]
Experiences and challenges of staying employed with chronic fatigue syndrome
on 7 novembre 2025
Author Names: Surendran G.,Jose T.P. Database Source: Embase Daily Updates Journal Title: Discover public health Article […]
A Perspective on the Role of Metformin in Treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID
on 7 novembre 2025
ACS Pharmacol Transl Sci. 2025 Sep 11;8(10):3411-3431. doi: 10.1021/acsptsci.5c00229. eCollection 2025 Oct 10.ABSTRACTMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID (LC) […]
Chronic Pain Prevalence, Characteristics, and Impact in United States Adults With Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
on 7 novembre 2025
Pain Manag Nurs. 2025 Oct 30:S1524-9042(25)00291-7. doi: 10.1016/j.pmn.2025.10.006. Online ahead of print.ABSTRACTPURPOSE: To determine the prevalence of chronic pain, describe characteristics of […]
Altered effort and deconditioning are not valid explanations of myalgic encephalomyelitis/chronic fatigue syndrome
on 7 novembre 2025
Nat Commun. 2025 Oct 17;16(1):9176. doi: 10.1038/s41467-025-64538-0.NO ABSTRACTPMID:41107289 | DOI:10.1038/s41467-025-64538-0
Understanding concussion in myalgic encephalomyelitis/chronic fatigue syndrome: Findings from the 2023 National Health Interview study
on 7 novembre 2025
Brain Inj. 2025 Oct 16:1-8. doi: 10.1080/02699052.2025.2575479. Online ahead of print.ABSTRACTBACKGROUND: Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) symptoms (dysautonomia, […]
The association of fatigue and pain with cognitive test performance in patients with myalgic encephalomyelitis/chronic fatigue syndrome
on 7 novembre 2025
J Psychosom Res. 2025 Oct 3;199:112401. doi: 10.1016/j.jpsychores.2025.112401. Online ahead of print.ABSTRACTOBJECTIVES: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) […]
Corticosteroids with low glucocorticoid activity as a potential therapeutic strategy for post-COVID-19 myalgic encephalomyelitis/chronic fatigue syndrome in patients with bipolar affective disorder: A case report
on 7 novembre 2025
PCN Rep. 2025 Oct 12;4(4):e70222. doi: 10.1002/pcn5.70222. eCollection 2025 Dec.ABSTRACTBACKGROUND: The COVID-19 pandemic has led to an increase in post-acute sequelae, including myalgic […]
Effects of recumbent isometric yoga on the daily functioning level of patients with myalgic encephalomyelitis/chronic fatigue syndrome: a randomized, controlled trial
on 7 novembre 2025
Biopsychosoc Med. 2025 Oct 10;19(1):19. doi: 10.1186/s13030-025-00339-7.ABSTRACTBACKGROUND: Although seated isometric yoga has been shown to reduce the fatigue and pain of patients with myalgic […]
First proposed blood test for chronic fatigue syndrome: what scientists think
on 7 novembre 2025
Nature. 2025 Oct 9. doi: 10.1038/d41586-025-03299-8. Online ahead of print.NO ABSTRACTPMID:41068441 | DOI:10.1038/d41586-025-03299-8
Systematic review: digital biomarkers of fatigue in chronic diseases
on 7 novembre 2025
NPJ Digit Med. 2025 Oct 8;8(1):602. doi: 10.1038/s41746-025-01939-x.ABSTRACTThis systematic review explores the relationship between digital biomarkers, measured using wearable devices, and fatigue […]
Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Physical Fatigue Through the Perspective of Immunosenescence
on 6 octobre 2025
Compr Physiol. 2025 Oct;15(5):e70056. doi: 10.1002/cph4.70056.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating illness marked by persistent fatigue, […]
The gut microbial composition is different in chronic fatigue syndrome than in healthy controls
on 6 octobre 2025
Sci Rep. 2025 Sep 26;15(1):33075. doi: 10.1038/s41598-025-16438-y.ABSTRACTThe pathogenesis of Chronic Fatigue Syndrome (CFS) is yet unknown. This study aimed to assess the gut microbial composition […]
In transfusion-dependent thalassemia, neuronal damage biomarkers are associated with affective and chronic fatigue symptoms
on 6 octobre 2025
Sci Rep. 2025 Sep 24;15(1):32721. doi: 10.1038/s41598-025-16757-0.ABSTRACTPatients with transfusion-dependent thalassemia (TDT) are vulnerable to neurotoxicity due to frequent blood transfusions and […]
Burden of Disease in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Scoping Review
on 6 octobre 2025
Appl Health Econ Health Policy. 2025 Sep 23. doi: 10.1007/s40258-025-01006-2. Online ahead of print.ABSTRACTOBJECTIVE: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious chronic […]
Advancing Digital Precision Medicine for Chronic Fatigue Syndrome through Longitudinal Large-Scale Multi-Modal Biological Omics Modeling with Machine Learning and Artificial Intelligence
on 6 octobre 2025
ArXiv [Preprint]. 2025 Jun 18:arXiv:2506.15761v1.ABSTRACTWe studied a generalized question: chronic diseases like ME/CFS and long COVID exhibit high heterogeneity with multifactorial etiology and […]
Comorbidity of chronic pain and fatigue : Common mechanisms, common treatment steps?
on 6 octobre 2025
Schmerz. 2025 Oct;39(5):322-328. doi: 10.1007/s00482-025-00898-2. Epub 2025 Aug 21.ABSTRACTFatigue and chronic pain show a high level of comorbidity and are both not only frequent symptoms of chronic […]
Solriamfetol improves daily fatigue symptoms in adults with myalgic encephalomyelitis/chronic fatigue syndrome after 8 weeks of treatment
on 6 octobre 2025
J Psychopharmacol. 2025 Sep 16:2698811251368371. doi: 10.1177/02698811251368371. Online ahead of print.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term […]

Syndrome d'Ehlers-Danlos

maladies_complexes_syndrome_ehlers_danlos 2 via biblio.chum on Inoreader

Comparative assessment of left common iliac vein compression in patients with hypermobile Ehlers-Danlos syndrome, hypermobility spectrum disorder and healthy controls - A retrospective single-centre study
on 5 Décembre 2025
Phlebology. 2025 Nov 17:2683555251400392. doi: 10.1177/02683555251400392. Online ahead of print.ABSTRACTObjectivesHeritable connective tissue disorders (HCTDs), including hypermobile Ehlers-Danlos […]
Associations Between Pain and Substance Use Among Individuals Diagnosed with Ehlers-Danlos Syndromes or Generalized Hypermobility Spectrum Disorder
on 5 Décembre 2025
Int J Behav Med. 2025 Nov 11. doi: 10.1007/s12529-025-10409-3. Online ahead of print.ABSTRACTBACKGROUND: Pain and substance use frequently co-occur. Research indicates pain motivates alcohol, […]
Connective tissue changes in Ehlers-Danlos syndromes with and without axial spondyloarthropathy
on 7 novembre 2025
J Ultrasound. 2025 Nov 4. doi: 10.1007/s40477-025-01092-x. Online ahead of print.ABSTRACTPURPOSE: Ehlers-Danlos Syndromes (EDS) are a group of connective tissue disorders characterized by joint […]
Co-morbid monogenic disorders at chromosome region 1q2: LMNA- and FLG-related disorders in a patient referred for assessment of joint hypermobility
on 7 novembre 2025
Chromosome Res. 2025 Oct 30;33(1):24. doi: 10.1007/s10577-025-09785-z.ABSTRACTThe phenotypic similarities and genetic heterogeneity occurring in diverse forms of Ehlers Danlos Syndrome (EDS) subtypes […]
Autonomic symptom burden, comorbidities and quality of life in women with Hypermobility Spectrum Disorders and hypermobile Ehlers-Danlos syndrome
on 7 novembre 2025
Auton Neurosci. 2025 Oct 14;262:103356. doi: 10.1016/j.autneu.2025.103356. Online ahead of print.ABSTRACTBACKGROUND: Hypermobility Spectrum Disorders (HSD) and hypermobile Ehlers-Danlos syndrome […]
Percutaneous transhepatic coil embolisation of a common hepatic artery aneurysm in vascular Ehlers-Danlos syndrome
on 7 novembre 2025
CVIR Endovasc. 2025 Oct 16;8(1):85. doi: 10.1186/s42155-025-00600-8.ABSTRACTBACKGROUND: Vascular Ehlers-Danlos syndrome is a rare connective tissue disorder characterised by arterial fragility, […]
Evidence of Altered Enteric Nervous System Structure Associated With Severe Dysmotility in a Patient With Ehlers-Danlos Syndrome
on 6 octobre 2025
ACG Case Rep J. 2025 Sep 24;12(9):e01823. doi: 10.14309/crj.0000000000001823. eCollection 2025 Sep.ABSTRACTPatients with Ehlers-Danlos syndrome (EDS) suffer from gastroparesis, constipation, and gut […]
Outcomes of revisional bariatric surgery in patient with hypermobile Ehlers-Danlos syndrome
on 6 octobre 2025
J Surg Case Rep. 2025 Sep 30;2025(9):rjaf782. doi: 10.1093/jscr/rjaf782. eCollection 2025 Sep.ABSTRACTEhlers-Danlos syndrome (EDS), a rare group of inherited connective tissue disorders caused by […]
Prevalence of Hypermobile Ehlers-Danlos Syndrome in Transgender and Gender Diverse Individuals: A Retrospective Cohort Study
on 6 octobre 2025
LGBT Health. 2025 Sep 23. doi: 10.1177/23258292251382250. Online ahead of print.ABSTRACTPurpose: This study compared the prevalence of hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility […]
Varied Presentations of Arterial Events in Vascular Ehlers-Danlos Syndrome
on 6 octobre 2025
JACC Case Rep. 2025 Sep 12:105424. doi: 10.1016/j.jaccas.2025.105424. Online ahead of print.ABSTRACTSpontaneous arterial aneurysms and dissections are relatively common in patients with vascular […]
Ehlers-Danlos syndromes: Diagnosis and care pathway of these complex and multisystemic diseases
on 1 septembre 2025
Rev Med Interne. 2025 Aug 30:S0248-8663(25)00722-2. doi: 10.1016/j.revmed.2025.08.002. Online ahead of print.ABSTRACTEhlers-Danlos syndromes (EDS) are a heterogeneous group of rare and inherited […]
A unique case of prenatal diagnosis of vascular Ehlers-Danlos syndrome
on 1 septembre 2025
Int J Gynaecol Obstet. 2025 Aug 7. doi: 10.1002/ijgo.70431. Online ahead of print.ABSTRACTWe present a rare instance of prenatal diagnosis of vEDS without a family history. The suspicion of a genetic […]
B3GALT6 mutations lead to compromised connective tissue biomechanics in Ehlers-Danlos syndrome
on 1 septembre 2025
JCI Insight. 2025 Aug 22;10(16):e179474. doi: 10.1172/jci.insight.179474. eCollection 2025 Aug 22.ABSTRACTEhlers-Danlos syndromes (EDS) comprise a genetically and clinically heterogenous group of […]
Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features
on 1 septembre 2025
Am J Med Open. 2025 Jul 18;14:100111. doi: 10.1016/j.ajmo.2025.100111. eCollection 2025 Dec.ABSTRACTBACKGROUND: Hypermobile Ehlers-Danlos syndrome (hEDS) affects multiple systems, but comprehensive […]
Association Between Ehlers-Danlos Syndrome and Celiac Disease
on 1 septembre 2025
Gastro Hep Adv. 2025 Jun 10;4(9):100719. doi: 10.1016/j.gastha.2025.100719. eCollection 2025.NO ABSTRACTPMID:40821885 | PMC:PMC12357298 | DOI:10.1016/j.gastha.2025.100719
Navigating the psychosocial landscape of Ehlers-Danlos syndrome: an autobiographic case study
on 1 septembre 2025
Discov Ment Health. 2025 Aug 17;5(1):123. doi: 10.1007/s44192-025-00268-5.ABSTRACTLiving with a rare disorder, such as Ehlers-Danlos Syndrome (EDS), presents unique psychosocial challenges. This […]
Health care supply in patients with Ehlers-Danlos syndromes and generalized hypermobility spectrum disorder: a German perspective
on 1 septembre 2025
Orphanet J Rare Dis. 2025 Aug 16;20(1):436. doi: 10.1186/s13023-025-03937-4.ABSTRACTBACKGROUND: Diagnosing Ehlers-Danlos syndromes (EDS) and EDS-related "hypermobility spectrum disorder" (HSD) is […]
Fragility in Focus: Gallbladder Rupture in a Patient With Vascular Ehlers-Danlos Syndrome
on 1 septembre 2025
ANZ J Surg. 2025 Aug 15. doi: 10.1111/ans.70298. Online ahead of print.ABSTRACTSpontaneous lumenal haemorrhage in gallbladder with subsequent rupture in patient with vascular variant Ehlers-Danlos […]
Vascular findings in five unrelated children with vascular Ehlers-Danlos syndrome: A multi-case report
on 1 septembre 2025
Eur J Med Genet. 2025 Aug 12:105035. doi: 10.1016/j.ejmg.2025.105035. Online ahead of print.ABSTRACTVascular Ehlers-Danlos syndrome (vEDS) is an inherited connective tissue disorder caused by […]
Risk factors of patellofemoral instability in patients with hypermobile Ehlers-Danlos syndrome
on 1 septembre 2025
Arch Orthop Trauma Surg. 2025 Aug 11;145(1):403. doi: 10.1007/s00402-025-06022-4.ABSTRACTPURPOSE: Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder characterized by joint […]

Études cliniques

maladies_complexes_etudes_cliniques via biblio.chum on Inoreader

PAxlovid loNg cOvid-19 pRevention triAl With recruitMent In the Community in Norway
on 5 Décembre 2025
Conditions: Post COVID-19 Condition, Unspecified; SARS-CoV2 Infection; COVID-19 Interventions: Drug: Nirmatrelvir/ritonavir; Drug: Placebo Sponsors: Haukeland University Hospital; University of […]
Psychosomatic, Physical Activity or Both for Post-covid19 Syndrom
on 5 Décembre 2025
Conditions: Post-COVID-19 Syndrome Interventions: Behavioral: Exercise Therapy; Behavioral: Psychotherapy Sponsors: Hannover Medical School; Health Insurance Audi BKK; occupational health service […]
Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
on 5 Décembre 2025
Conditions: Post-acute Sequelae of SARS-CoV-2 Infection Interventions: Behavioral: Exercise Sponsors: University of Colorado, Denver Recruiting
Harnessing Optimism and Perseverance in the Face of Long COVID-Español
on 7 novembre 2025
Conditions: Post-Acute COVID-19 Syndrome Interventions: Behavioral: HOPE-LC~Espanol Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting
LIFT: Life Improvement Trial
on 7 novembre 2025
Conditions: ME/CFS; Long COVID; PASC Interventions: Drug: Pyridostigmine; Drug: Low-Dose Naltrexone; Other: Placebo Sponsors: Brigham and Women's Hospital; Open Medicine Foundation Recruiting
Development of Voice Biomarkers of Frequent COVID-19 and Long Covid-related Symptoms Based on Data From Users of the Long COVID Companion App
on 3 octobre 2025
Conditions: Long COVID Interventions: Other: No Intervention: Observational Cohort Sponsors: Luxembourg Institute of Health Not yet recruiting
Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome
on 3 octobre 2025
Conditions: Post-COVID-19 Syndrome Interventions: Behavioral: Complementary self-help strategies in addition to treatment as usual; Other: Treatment as usual Sponsors: Universität Duisburg-Essen […]
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
on 3 octobre 2025
Conditions: Fatigue; Post-Acute COVID-19 Syndrome Interventions: Procedure: Immunoadsorption vs. sham immunoadsorption Sponsors: Hannover Medical School Completed
Chronic Stress as a Risk Factor for Long COVID
on 3 octobre 2025
Conditions: Long COVID; Acute COVID-19 Sponsors: Medical University of Graz; University of Klagenfurt; Wayne State University Completed
Transcranial Ultrasound Stimulation for Cognitive Function Modulation in Patients With Post COVID-19 Brain Fog
on 3 octobre 2025
Conditions: COVID-19; Brain Fog; Long COVID; Transcranial Ultrasound Stimulation Interventions: Device: sham transcranial ultrasound stimulation; Device: real transcranial ultrasound stimulation […]
Visualizing Regional Lung Ventilation in Patients With Postacute-COVID-19
on 3 octobre 2025
Conditions: Ventilatory Defect; COVID-19; Post-acute COVID-19 Syndrome; Electric Impedance Tomography; Post-COVID-19 Syndrome Sponsors: Jan-Christoph Lewejohann Completed
Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome
on 3 octobre 2025
Conditions: Post COVID-19 Syndrome Interventions: Biological: HB-adMSCs (allogeneic); Other: Placebo Sponsors: Hope Biosciences Research Foundation Completed
Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19
on 3 octobre 2025
Conditions: COVID-19 Pneumonia; Post-acute COVID-19 Syndrome; Electric Impedance Interventions: Diagnostic Test: additional EIT Measurement Sponsors: Jan-Christoph Lewejohann Not yet recruiting
Transcranial Pulse Stimulation (TPS) in Post-COVID-19
on 3 octobre 2025
Conditions: Post-COVID-19 Syndrome; Fatigue Interventions: Device: Transcranial pulse stimulation Verum; Device: Transcranial pulse stimulation Sham Sponsors: Medical University of Vienna […]
Intermediate Size Expanded Access Protocol for the Treatment of Post-COVID-19 Syndrome
on 3 octobre 2025
Conditions: Post COVID-19 Syndrome Interventions: Biological: HB-adMSCs Sponsors: Hope Biosciences Research Foundation No longer available
IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 Condition
on 3 octobre 2025
Conditions: Depressive Disorder; Post-Acute COVID-19 Syndrome Interventions: Device: Intermittent theta-burst stimulation (iTBS) using PowerMAG 100 ppTMS Sponsors: Max-Planck-Institute of […]
Characterization of the Immunometabolic Signature in Long COVID-19.
on 3 octobre 2025
Conditions: Long COVID Interventions: Biological: Blood sample (at inclusion and 6 months later); Other: Patient questionnaires (at inclusion and 6 months later) Sponsors: University Hospital, […]
Vagal Approaches on Long COVID
on 3 octobre 2025
Conditions: Long COVID Symptoms Interventions: Other: Sonocea Sonic Augmentation Technology (SAT); Other: Truvaga Electrical Vagus Nerve Stimulator Sponsors: Leidos Life Sciences Not yet recruiting
Mechanism of Isolevuglandin-Protein Adduct Formation in Persistent Immune Activation in Long COVID POTS
on 3 octobre 2025
Conditions: Post-Acute COVID-19 Syndrome; Postural Tachycardia Syndrome (POTS); SARS CoV 2 Infection; Long COVID19 Interventions: Drug: To Measure levels of circulating monocyte/ T cell doublets at […]
CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication
on 3 octobre 2025
Conditions: COVID-19; Long COVID; Post COVID-19 Condition Interventions: Other: no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and […]

Revue d'actualités

maladies_complexes_actualites via biblio.chum on Inoreader

Resistance Training Improves Long COVID Outcomes
on 5 Décembre 2025
JAMA. 2025 Nov 21. doi: 10.1001/jama.2025.19746. Online ahead of print.NO ABSTRACTPMID:41269680 | DOI:10.1001/jama.2025.19746
U of A research explores reasons for higher long-COVID rate among women - CTV News
on 5 Décembre 2025
U of A research explores reasons for higher long-COVID rate among women CTV News
8 trajectories for long COVID - Harvard Gazette
on 3 Décembre 2025
8 trajectories for long COVID Harvard Gazette
Why women may experience long COVID at a higher rate than men - CTV News
on 3 Décembre 2025
Why women may experience long COVID at a higher rate than men CTV News
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease - The Lancet
on 3 Décembre 2025
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease The Lancet
Valneva annonce des résultats finaux positifs de Phase 2 pour son candidat vaccin contre la maladie de Lyme - lesoleil.com
on 3 Décembre 2025
Valneva annonce des résultats finaux positifs de Phase 2 pour son candidat vaccin contre la maladie de Lyme lesoleil.com
Why is ‘chronic’ lyme disease so controversial? – podcast
on 7 novembre 2025
Long COVID is here to stay—even in children - The Lancet
on 7 novembre 2025
Long COVID is here to stay—even in children The Lancet
New research sheds light on why brain fog is a common symptom of long COVID. - Psychology Today
on 7 novembre 2025
New research sheds light on why brain fog is a common symptom of long COVID. Psychology Today
Scientists may have discovered what’s behind long COVID-related brain fog - Toronto Star
on 7 novembre 2025
Scientists may have discovered what’s behind long COVID-related brain fog Toronto Star
Vivre avec la COVID longue : une exposition donne la parole aux malades - Radio-Canada
on 7 novembre 2025
Vivre avec la COVID longue : une exposition donne la parole aux malades Radio-Canada
Enfin de l’espoir pour le syndrome de fatigue chronique - Le Devoir
on 7 novembre 2025
Enfin de l’espoir pour le syndrome de fatigue chronique Le Devoir
Lyme disease: 'My independence is gone completely' after tick bite - BBC
on 6 octobre 2025
Lyme disease: 'My independence is gone completely' after tick bite BBC
RFK Jr. nomme un chercheur controversé à la tête d’un comité sur la COVID longue - Radio-Canada
on 3 octobre 2025
RFK Jr. nomme un chercheur controversé à la tête d’un comité sur la COVID longue Radio-Canada
Estrie | Une nouvelle fièvre transmise par une tique est recensée - La Presse
on 1 septembre 2025
Estrie | Une nouvelle fièvre transmise par une tique est recensée La Presse
Les dérives de la maladie de Lyme | Bonsoir bonsoir! - Radio-Canada
on 1 septembre 2025
Les dérives de la maladie de Lyme | Bonsoir bonsoir! Radio-Canada
COVID longue et retour à la vie professionnelle : pas tout le monde est chanceux - Radio-Canada
on 10 juillet 2025
COVID longue et retour à la vie professionnelle : pas tout le monde est chanceux Radio-Canada
COVID longue : fin d’un programme à l’Hôpital d’Ottawa - Radio-Canada
on 10 juillet 2025
COVID longue : fin d’un programme à l’Hôpital d’Ottawa Radio-Canada
Santé Québec, symptôme d’incertitude pour les soins de COVID longue - Le Quotidien
on 10 juillet 2025
Santé Québec, symptôme d’incertitude pour les soins de COVID longue Le Quotidien
COVID longue: des tests à l'effort essentiels pour évaluer les séquelles cardiorespiratoires - ULaval nouvelles
on 10 juillet 2025
COVID longue: des tests à l'effort essentiels pour évaluer les séquelles cardiorespiratoires ULaval nouvelles

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