Maladies complexes

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COVID longue

maladies_complexes_covid_longue via biblio.chum on Inoreader

Genetic Landscape and Mitochondrial Metabolic Dysregulation in Patients Suffering From Severe Long COVID
on 3 mars 2025
J Med Virol. 2025 Mar;97(3):e70275. doi: 10.1002/jmv.70275.ABSTRACTLong COVID represents a significant global health challenge with an unclear etiology. Alongside accumulating evidence of mitochondrial dysfunction in patients with acute SARS-CoV-2 […]
Respiratory long COVID in aged hamsters features impaired lung function post-exercise with bronchiolization and fibrosis
on 3 mars 2025
Nat Commun. 2025 Feb 28;16(1):2080. doi: 10.1038/s41467-025-57267-x.ABSTRACTLong-term consequences of SARS-CoV-2 infection affect millions of people and strain public health systems. The underlying pathomechanisms remain unclear, necessitating […]
Rehabilitation interventions and outcomes for post-COVID condition: a scoping review
on 3 mars 2025
BMJ Public Health. 2025 Feb 26;3(1):e001827. doi: 10.1136/bmjph-2024-001827. eCollection 2025 Jan.ABSTRACTOBJECTIVE: Several rehabilitation interventions have been proposed to support people with post-COVID-19 condition (PCC). However, the full […]
Post-COVID-19 condition in prospective inpatient and outpatient cohorts
on 3 mars 2025
Sci Rep. 2025 Feb 26;15(1):6925. doi: 10.1038/s41598-025-90819-1.ABSTRACTViral persistence, immune dysregulation, hypocortisolism, and pulmonary tissue damage from acute infection are proposed as pathogenic mechanisms underlying post-COVID-19 […]
Factors associated with reduction in quality of life after SARS-CoV-2 infection
on 3 mars 2025
Sci Rep. 2025 Feb 26;15(1):6833. doi: 10.1038/s41598-025-91388-z.ABSTRACTLong-term changes in health-related quality of life (HrQoL) after SARS-CoV-2 infection are common, but their causes and consequences are poorly understood. This prospective, […]
Identification of a multi-omics factor predictive of long COVID in the IMPACC study
on 3 mars 2025
bioRxiv [Preprint]. 2025 Feb 14:2025.02.12.637926. doi: 10.1101/2025.02.12.637926.ABSTRACTFollowing SARS-CoV-2 infection, ∼10-35% of COVID-19 patients experience long COVID (LC), in which often debilitating symptoms persist for at least three […]
Altered corticostriatal connectivity in long-COVID patients is associated with cognitive impairment
on 3 mars 2025
Psychol Med. 2025 Feb 17;55:e49. doi: 10.1017/S0033291725000054.ABSTRACTBACKGROUND: The COVID-19 pandemic has had a significant impact on the health of millions of people worldwide, and many manifest new or persistent symptoms long after the initial […]
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment
on 3 mars 2025
JACC Basic Transl Sci. 2024 Nov 27;10(1):20-39. doi: 10.1016/j.jacbts.2024.09.007. eCollection 2025 Jan.ABSTRACTIn the present study, we provide evidence on the potential mechanisms involved in the residual pulmonary impairment described in long […]
Autoimmunity in Long-COVID
on 3 mars 2025
J Allergy Clin Immunol. 2025 Feb 14:S0091-6749(25)00171-X. doi: 10.1016/j.jaci.2025.02.005. Online ahead of print.ABSTRACTLong-COVID (also termed Post-Acute Sequelae of SARS-CoV-2 or PASC) affects up to 10% of people recovering from SARS-CoV-2 […]
Higher Prevalence of Long COVID Observed in Cancer Survivors: Insights from a US Nationwide Survey
on 3 mars 2025
Ann Epidemiol. 2025 Feb 11:S1047-2797(25)00030-4. doi: 10.1016/j.annepidem.2025.02.004. Online ahead of print.ABSTRACTBACKGROUND: Cancer and cancer treatments can weaken the body's immune system, making cancer patients particularly vulnerable to […]
Targeting the SARS-CoV-2 reservoir in long COVID - The Lancet
on 3 mars 2025
Targeting the SARS-CoV-2 reservoir in long COVID The Lancet
Differences in Long COVID severity by duration of illness, symptom evolution, and vaccination: a longitudinal cohort study from the INSPIRE group - The Lancet
on 3 mars 2025
Differences in Long COVID severity by duration of illness, symptom evolution, and vaccination: a longitudinal cohort study from the INSPIRE group The Lancet
Identifying and mitigating the public health consequences of meta-ignorance about "Long COVID" risks
on 13 février 2025
Public Health. 2025 Feb 11;241:19-23. doi: 10.1016/j.puhe.2025.02.003. Online ahead of print.ABSTRACTOBJECTIVES: While past work studies public concern about "Long COVID," fewer have asked what the public knows and/or purports to know about Long […]
Association between chronic fatigue syndrome/myalgic encephalomyelitis and cardiovascular disease
on 11 février 2025
Sci Rep. 2025 Jan 17;15(1):2294. doi: 10.1038/s41598-025-86609-4.ABSTRACTChronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a medical condition characterized by severe and prolonged fatigue that is not relieved by rest or attributed […]
Long covid as a long term condition
on 11 février 2025
BMJ Med. 2025 Jan 31;4(1):e001366. doi: 10.1136/bmjmed-2025-001366. eCollection 2025 Jan.NO ABSTRACTPMID:39906532 | PMC:PMC11792270 | DOI:10.1136/bmjmed-2025-001366
Interventions for the management of post-COVID-19 condition (long COVID): protocol for a living systematic review and network meta-analysis
on 11 février 2025
BMJ Open. 2025 Feb 7;15(2):e086407. doi: 10.1136/bmjopen-2024-086407.ABSTRACTBACKGROUND: Up to 15% of survivors of COVID-19 infection experience long-term health effects, including fatigue, myalgia and impaired cognitive function, termed […]
Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient intervention setting with an online control group register
on 11 février 2025
BMJ Open. 2025 Feb 7;15(2):e098574. doi: 10.1136/bmjopen-2024-098574.ABSTRACTINTRODUCTION: Energy management education (EME) is a manualised, evidence-based self-management education programme developed and delivered by occupational therapists for […]
Prevalence and Impact of Post-Exertional Malaise on Recovery in Adults with Post COVID-19 Condition. A Systematic Review with Meta-Analysis
on 11 février 2025
Arch Phys Med Rehabil. 2025 Feb 5:S0003-9993(25)00501-5. doi: 10.1016/j.apmr.2025.01.471. Online ahead of print.ABSTRACTOBJECTIVE: To assess the prevalence of PEM in people with PCC; and the change in prevalence of PEM following rehabilitation […]
Classifying COVID-19 hospitalizations in epidemiology cohort studies: The C4R study
on 11 février 2025
PLoS One. 2025 Feb 10;20(2):e0316198. doi: 10.1371/journal.pone.0316198. eCollection 2025.ABSTRACTRATIONALE: Robust COVID-19 outcomes classification is important for ongoing epidemiology research on acute and post-acute COVID-19 conditions. […]
Long COVID Prevalence and Associated Activity Limitation in US Children
on 11 février 2025
JAMA Pediatr. 2025 Feb 3. doi: 10.1001/jamapediatrics.2024.6206. Online ahead of print.NO ABSTRACTPMID:39899316 | DOI:10.1001/jamapediatrics.2024.6206

COVID longue : lignes directrices canadiennes

Mise à jour du 5 février 2025

Maladie de Lyme

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Borrelia spielmanii-Associated Neuroborreliosis in Patient Receiving Rituximab, Belgium
on 3 mars 2025
Emerg Infect Dis. 2025 Feb;31(2):341-344. doi: 10.3201/eid3102.240777.ABSTRACTA 58-year-old woman in Belgium with a history of follicular lymphoma treated with rituximab sought care for a rapid sensory-motor deficit. Seronegative neuroborreliosis […]
Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity
on 3 mars 2025
Commun Biol. 2025 Mar 1;8(1):341. doi: 10.1038/s42003-025-07781-x.ABSTRACTHigh-temperature requirement protease A (HtrA) is a family of serine proteases that regulate bacterial stress response through controlling protein quality. This report shows […]
A type-specific B-cell epitope at the apex of outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi
on 3 mars 2025
Microbiol Spectr. 2025 Feb 14:e0288324. doi: 10.1128/spectrum.02883-24. Online ahead of print.ABSTRACTBroadly protective immunity to the Lyme disease spirochete, Borreliella burgdorferi, is constrained by antibodies against type-specific epitopes on […]
Borréliose de Lyme et autres maladies vectorielles à tiques : la HAS actualise ses recommandations - Haute Autorité de Santé
on 3 mars 2025
Borréliose de Lyme et autres maladies vectorielles à tiques : la HAS actualise ses recommandations Haute Autorité de Santé
Dose Evaluation and Optimization of Amoxicillin in Children Treated for Lyme Disease
on 13 février 2025
J Clin Pharmacol. 2025 Jan 27. doi: 10.1002/jcph.6190. Online ahead of print.ABSTRACTAmoxicillin is commonly used to treat erythema migrans in the first stage of Lyme disease in children, with a recommended dose of 50 mg/kg/day, administered three […]
Lyme disease associated neurological and musculoskeletal symptoms: A systematic review and meta-analysis
on 13 février 2025
Brain Behav Immun Health. 2025 Jan 2;43:100931. doi: 10.1016/j.bbih.2024.100931. eCollection 2025 Feb.ABSTRACTBACKGROUND AND OBJECTIVE: Lyme disease, caused by Borrelia burgdorferi, presents major health challenges worldwide, leading to serious […]
Lyme neuroborreliosis in Japan: Borrelia burgdorferi sensu lato as a cause of meningitis of previously undetermined etiology in hospitalized patients outside of the island of Hokkaido, 2010-2021
on 15 janvier 2025
Eur J Neurol. 2025 Jan;32(1):e70005. doi: 10.1111/ene.70005.ABSTRACTBACKGROUND AND PURPOSE: Clinical manifestations of Lyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato (Bbsl), include erythema migrans, Lyme neuroborreliosis (LNB), […]
Perspective: Incidence of Clinician-Diagnosed Lyme Disease in Manitoba, Canada 2009-2018
on 15 janvier 2025
Vector Borne Zoonotic Dis. 2025 Jan 6. doi: 10.1089/vbz.2024.0088. Online ahead of print.ABSTRACTIntroduction: Lyme disease (LD) surveillance yields useful information to monitor the disease trends and spatial distribution. However, due to several […]
Clinical characteristics and serological profiles of Lyme disease in children: a 15-year retrospective cohort study in Switzerland
on 15 janvier 2025
Lancet Reg Health Eur. 2024 Dec 9;48:101143. doi: 10.1016/j.lanepe.2024.101143. eCollection 2025 Jan.ABSTRACTBACKGROUND: Lyme disease (LD) is caused by Borrelia burgdorferi and is the most common tickborne disease in the northern hemisphere. […]
The Current and Future State of Vaccines for Lyme Disease
on 15 janvier 2025
Clin Infect Dis. 2024 Dec 23:ciae639. doi: 10.1093/cid/ciae639. Online ahead of print.ABSTRACTLyme disease is caused by Borrelia species that are transmitted by Ixodes ticks prevalent in parts of the United States and Europe. A Lyme vaccine […]
bb0689 contributes to the virulence of Borrelia burgdorferi in a murine model of Lyme disease
on 20 Décembre 2024
Infect Immun. 2024 Dec 16:e0045924. doi: 10.1128/iai.00459-24. Online ahead of print.ABSTRACTBorrelia burgdorferi, the Lyme disease pathogen, continuously changes its gene expression profile in order to adapt to ticks and mammalian hosts. The […]
Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice
on 20 Décembre 2024
Nat Commun. 2024 Nov 29;15(1):10417. doi: 10.1038/s41467-024-54806-w.ABSTRACTFlagella propel pathogens through their environments, yet are expensive to synthesize and are immunogenic. Thus, complex hierarchical regulatory networks control flagellar […]
Anti-RA33 Antibodies Are Present in Patients With Lyme Disease
on 20 Décembre 2024
J Clin Rheumatol. 2024 Nov 22. doi: 10.1097/RHU.0000000000002176. Online ahead of print.ABSTRACTBACKGROUND/OBJECTIVE: To determine if anti-RA33 antibodies, which can be seen in early forms of inflammatory arthritis, are present in patients with Lyme […]
Historical Summary of Tick and Animal Surveillance Studies for Lyme Disease in Canada, 1975-2023: A Scoping Review
on 20 Décembre 2024
Zoonoses Public Health. 2024 Nov 22. doi: 10.1111/zph.13191. Online ahead of print.ABSTRACTINTRODUCTION: Lyme disease (LD) is caused by infection with the bacteria Borrelia burgdorferi sensu lato (Bb) through the bite of an infected Ixodes spp. […]
Upcoming Events - Lyme Care Resource Center
on 15 novembre 2024
Invalidation, gender, and the medical encounter in Lyme disease Tuesday, November 19th, 2024, 7:00- 8:30pm EST Alison Rebman, MPH earned her graduate degree from Columbia University in Sociomedical Sciences. She is currently an […]
Identifying the geographic leading edge of Lyme disease in the United States with internet searches: A spatiotemporal analysis of Google Health Trends data
on 15 novembre 2024
PLoS One. 2024 Nov 13;19(11):e0312277. doi: 10.1371/journal.pone.0312277. eCollection 2024.ABSTRACTBACKGROUND: The geographic footprint of Lyme disease is expanding in the United States, which calls for novel methods to identify emerging endemic […]
Lyme disease health-related quality of life and resilience: A gender comparative study.
on 6 novembre 2024
Author Names: Bancsi, Dawn Denisesinicki Database Source: APA PsycInfo <January 2024 Week 1 to October 2024 Week 5> Journal Title: Dissertation Abstracts International Section A: […]
Cardiac Manifestations of Lyme Disease
on 5 novembre 2024
Cardiol Rev. 2024 Oct 24. doi: 10.1097/CRD.0000000000000807. Online ahead of print.ABSTRACTLyme disease (LD) is an inflammatory disorder caused by an infectious bacterial agent and is the most common tick-borne illness in the United States and […]
Initial symptoms and late complication in Lyme neuroborreliosis from the perspective of patients and relatives: a qualitative study
on 5 novembre 2024
BMC Prim Care. 2024 Oct 23;25(1):379. doi: 10.1186/s12875-024-02624-w.ABSTRACTBACKGROUND: Lyme borreliosis is by far the most common vector-borne infection in Western Europe. The most severe manifestation of Lyme borreliosis is Lyme neuroborreliosis […]
Incidence of hospitalizations related to Lyme disease and other tick-borne diseases using Discharge Abstract Database, Canada, 2009-2021
on 5 novembre 2024
PLoS One. 2024 Oct 25;19(10):e0312703. doi: 10.1371/journal.pone.0312703. eCollection 2024.ABSTRACTTo estimate rates of hospitalizations for tick-borne diseases (TBDs) in Canada, retrospective analysis was conducted to determine the incidence of […]

Encéphalomyélite myalgique

maladies_complexes_encephalomyelite via biblio.chum on Inoreader

Mapping the Complexity of ME/CFS: Evidence for Abnormal Energy Metabolism, Altered Immune Profile and Vascular Dysfunction
on 3 mars 2025
Author Names: Heng R.B.,Gunasegaran B.,Krishnamurthy S.,Bustamante S.,Pires A.S.,Chow S.,Ahn S.B.,Paul-Heng M.,Maciver Y.,Smith K.,Tran D.P.,Howley P.P.,Bilgin A.A.,Sharland A.,Schloeffel R.,Guillemin G.J. Database Source: […]
Chronic Fatigue Syndrome: Pulling Back the Curtains
on 3 mars 2025
Author Names: anonymous Database Source: Embase Daily Updates Journal Title: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Article […]
A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis - chronic fatigue syndrome
on 3 mars 2025
Author Names: Hirsch A.G.,Justice A.E.,Poissant A.,Nordberg C.M.,Josyula N.S.,Aucott J.,Rebman A.W.,Schwartz B.S. Database Source: Embase Daily Updates Journal Title: BMC Infectious Diseases […]
Cerebrospinal fluid metabolomics, lipidomics and serine pathway dysfunction in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS)
on 3 mars 2025
Sci Rep. 2025 Mar 3;15(1):7381. doi: 10.1038/s41598-025-91324-1.ABSTRACTWe proposed that cerebrospinal fluid would provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS). The concept […]
A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis - chronic fatigue syndrome
on 3 mars 2025
BMC Infect Dis. 2025 Feb 24;25(1):265. doi: 10.1186/s12879-024-10238-x.ABSTRACTBACKGROUND: Up to 20% of Lyme disease cases experience post-treatment Lyme disease syndrome (PTLDS). The biological basis for PTLDS is poorly understood and no […]
Managing Energy, and Shaping Care: Insights from Adults with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Through Co-Production Workshops
on 3 mars 2025
Am J Med. 2025 Feb 15:S0002-9343(25)00093-2. doi: 10.1016/j.amjmed.2025.02.008. Online ahead of print.ABSTRACTBACKGROUND: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, debilitating condition characterised by severe […]
Cognitive functioning in patients with chronic fatigue syndrome: Slowed information processing or a deficit in attentional selectivity?
on 3 mars 2025
Neuropsychology. 2025 Feb;39(2):152-161. doi: 10.1037/neu0000982.ABSTRACTOBJECTIVE: By addressing numerous statistical, theoretical, and methodological weaknesses of existing research on chronic fatigue syndrome (CFS), this study attempted to […]
Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
on 11 février 2025
medRxiv [Preprint]. 2025 Jan 6:2025.01.02.24319359. doi: 10.1101/2025.01.02.24319359.ABSTRACTMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating but poorly-understood disease. ME/CFS symptoms can range from mild to severe, […]
Provocation of brachial plexus and systemic symptoms during the elevated arm stress test in individuals with myalgic encephalomyelitis/chronic fatigue syndrome or idiopathic chronic fatigue
on 11 février 2025
J Transl Med. 2025 Jan 22;23(1):106. doi: 10.1186/s12967-025-06137-7.ABSTRACTBACKGROUND: We have noted that some adolescents and young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) report difficulty with arms-overhead […]
The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology
on 11 février 2025
J Transl Med. 2025 Feb 4;23(1):149. doi: 10.1186/s12967-025-06146-6.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease of unknown aetiology characterised by symptoms of post-exertional malaise (PEM) and […]
Chronic Fatigue Syndrome: Pulling Back the Curtains
on 11 février 2025
Neuroscientist. 2025 Feb;31(1):5. doi: 10.1177/10738584241308723.NO ABSTRACTPMID:39927439 | DOI:10.1177/10738584241308723
Exercise therapy for chronic fatigue syndrome - PubMed
on 15 janvier 2025
Editorial note: Editorial note (19 December 2024): Larun L, Brurberg KG, Odgaard‐Jensen J, Price JR. Exercise therapy for chronic fatigue syndrome. Cochrane Database of Systematic Reviews 2019, Issue 10. Art. No.: CD003200. DOI: […]
Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study
on 15 janvier 2025
J Gen Intern Med. 2025 Jan 13. doi: 10.1007/s11606-024-09290-9. Online ahead of print.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 […]
Machine learning and multi-omics in precision medicine for ME/CFS
on 15 janvier 2025
J Transl Med. 2025 Jan 14;23(1):68. doi: 10.1186/s12967-024-05915-z.ABSTRACTMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and multifaceted disorder that defies simplistic characterisation. Traditional approaches to […]
Efficacy of repeated immunoadsorption in patients with post-COVID myalgic encephalomyelitis/chronic fatigue syndrome and elevated beta2-adrenergic receptor autoantibodies: a prospective cohort study
on 15 janvier 2025
Lancet Reg Health Eur. 2024 Dec 12;49:101161. doi: 10.1016/j.lanepe.2024.101161. eCollection 2025 Feb.ABSTRACTBACKGROUND: Since the pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the leading trigger for myalgic […]
Re-visiting professional ethics in psychotherapy: reflections on the use of talking therapies as a supportive adjunct for myalgic encephalomyelitis/chronic fatigue syndrome and 'medically unexplained symptoms'
on 15 janvier 2025
J Med Ethics. 2024 Dec 31:jme-2023-109627. doi: 10.1136/jme-2023-109627. Online ahead of print.ABSTRACTFollowing years of debate over the effectiveness of cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), […]
Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Accumulated Evidence
on 15 janvier 2025
J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13669. doi: 10.1002/jcsm.13669.ABSTRACTBACKGROUND: Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). […]
A novel frameshift mutation in ADCK1 identified in a case of chronic fatigue syndrome successfully treated with oral 5-ALA/SFC
on 15 janvier 2025
Immunol Med. 2024 Dec 26:1-5. doi: 10.1080/25785826.2024.2445399. Online ahead of print.ABSTRACTChronic Fatigue Syndrome (CFS) is a complex disorder characterized by prolonged, unexplained fatigue and challenging diagnosis. We report the case of a […]
Oral minocycline therapy as first-line treatment in patients with Myalgic encephalomyelitis and long COVID: A pilot study
on 15 janvier 2025
eNeurologicalSci. 2024 Dec 2;38:100537. doi: 10.1016/j.ensci.2024.100537. eCollection 2025 Mar.ABSTRACTBACKGROUND: Myalgic encephalomyelitis (ME) is associated with long COVID and also untoward sequelae after anti-coronavirus vaccination. Recently, […]
The potential of plasma exchange in treating Chronic Fatigue Syndrome and long COVID: Targeting autoimmune and inflammatory mechanisms
on 20 Décembre 2024
Author Names: Akgun Y. Database Source: Embase Daily Updates Journal Title: Transfusion,Transfusion Article Title: The potential of plasma exchange in treating […]

Syndrome d'Ehlers-Danlos

maladies_complexes_syndrome_ehlers_danlos 2 via biblio.chum on Inoreader

Recurrent perforation of an implantable cardioverter-defibrillator lead in a patient with vascular Ehlers-Danlos syndrome
on 3 mars 2025
HeartRhythm Case Rep. 2024 Oct 18;11(2):101-103. doi: 10.1016/j.hrcr.2024.10.015. eCollection 2025 Feb.NO ABSTRACTPMID:40018318 | PMC:PMC11862159 | DOI:10.1016/j.hrcr.2024.10.015
Navigating HOPE (Hypermobile Online Pain managemEnt): Perspectives and Experiences From People With Hypermobile Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder on a Condition-Specific Online Pain Management Programme
on 3 mars 2025
Health Expect. 2025 Feb;28(1):e70186. doi: 10.1111/hex.70186.ABSTRACTINTRODUCTION: The Hypermobile Online Pain managemEnt (HOPE) programme is a stakeholder informed intervention adopting the biopsychosocial pain approach, specifically for people […]
Rates of mental health concerns among individuals assessed at the GoodHope Ehlers-Danlos Syndrome Clinic
on 3 mars 2025
Orphanet J Rare Dis. 2025 Feb 14;20(1):75. doi: 10.1186/s13023-025-03550-5.ABSTRACTPast research has indicated that individuals with Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobililty Spectrum Disorder (G-HSD) report psychological and […]
Regulation of Joint Tissues and Joint Function: Is There Potential for Lessons to Be Learned Regarding Regulatory Control from Joint Hypermobility Syndromes?
on 13 février 2025
Int J Mol Sci. 2025 Jan 31;26(3):1256. doi: 10.3390/ijms26031256.ABSTRACTNormal development of joints starts in utero with the establishment of a cellular and extracellular matrix template. Following birth, individual joint tissues grow and mature […]
The Impact of Pain on Everyday Activities of People With Hypermobility Spectrum Disorders or Hypermobility Ehlers Danlos Syndrome
on 13 février 2025
Eur J Pain. 2025 Mar;29(3):e70000. doi: 10.1002/ejp.70000.ABSTRACTBACKGROUND: This study describes aspects of pain and how pain affects everyday life and examines the relation between chronic pain and activity limitations in people with […]
Efficacy of Irbesartan in Celiprolol-Treated Patients With Vascular Ehlers-Danlos Syndrome
on 13 février 2025
Circulation. 2025 Feb 5. doi: 10.1161/CIRCULATIONAHA.124.072849. Online ahead of print.ABSTRACTBACKGROUND: Vascular Ehlers-Danlos syndrome is a rare genetic disorder characterized by defective type III collagen and a high risk of arterial morbidity […]
Pediatrics. Diagnosis of generalized joint hypermobility in children
on 13 février 2025
Rev Med Suisse. 2025 Jan 29;21(903):200-204. doi: 10.53738/REVMED.2025.21.903.200.ABSTRACTJoint hypermobility is a common feature in children and adolescents, often physiological and benign, but it is also a manifestation of hereditary connective […]
The prevalence of hypermobile Ehlers-Danlos syndrome at a gender-affirming primary care clinic
on 13 février 2025
SAGE Open Med. 2025 Jan 22;13:20503121251315021. doi: 10.1177/20503121251315021. eCollection 2025.ABSTRACTOBJECTIVE: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that […]
Outcomes of Total Joint Arthroplasty in Patients Who Have Ehlers-Danlos Syndrome: A Systematic Review and Meta-Analysis
on 13 février 2025
J Arthroplasty. 2025 Jan 20:S0883-5403(25)00033-6. doi: 10.1016/j.arth.2025.01.018. Online ahead of print.ABSTRACTBACKGROUND: Patients who have Ehlers-Danlos Syndrome (EDS), a group of connective tissue disorders characterized by aberrant collagen […]
Trends in surgical procedures for shoulder instability among patients with Ehlers-Danlos syndrome or joint hypermobility syndrome
on 13 février 2025
JSES Int. 2024 Aug 27;8(6):1164-1168. doi: 10.1016/j.jseint.2024.08.178. eCollection 2024 Nov.ABSTRACTBACKGROUND: Joint hypermobility syndrome (JHS) and Ehlers-Danlos Syndrome (EDS) are connective tissue disorders characterized by increased joint […]
Tenascin-X deficiency causing classical-like Ehlers Danlos syndrome type 1 in humans is a significant risk factor for GI and tracheal ruptures
on 15 janvier 2025
Clin Transl Gastroenterol. 2025 Jan 14. doi: 10.14309/ctg.0000000000000821. Online ahead of print.ABSTRACTBACKGROUND: Classical-like Ehlers Danlos Syndrome type 1 (clEDS1) is a very rare form of Ehlers Danlos Syndrome (EDS) caused by tenascin-X […]
Hypermobile type Ehlers-Danlos syndrome and generalized hypermobile spectrum disorder treatment preferences - a cross-sectional survey of patients
on 15 janvier 2025
Rheumatol Int. 2025 Jan 13;45(1):25. doi: 10.1007/s00296-024-05782-3.ABSTRACTWe aimed to assess the typical experiences, desired outcomes, satisfaction with clinical and anticipated outcomes, and the importance of improvements for individuals with […]
The Financial Impact of Ehlers-Danlos Syndromes on Patients in the United States in 2022
on 15 janvier 2025
Mayo Clin Proc Innov Qual Outcomes. 2024 Dec 14;9(1):100586. doi: 10.1016/j.mayocpiqo.2024.11.003. eCollection 2025 Feb.ABSTRACTOBJECTIVE: To determine the financial impact of Ehlers-Danlos syndromes (EDS) on patients in the United States by […]
Exploring fatigue in Marfan and hypermobile Ehlers-Danlos syndromes: an analytical cross-sectional study in two Italian healthcare centres
on 15 janvier 2025
BMJ Open. 2025 Jan 6;15(1):e087298. doi: 10.1136/bmjopen-2024-087298.ABSTRACTOBJECTIVE: This study investigates the prevalence and underlying factors of fatigue in individuals with Marfan syndrome (MFS) and hypermobile Ehlers-Danlos syndromes […]
Rare vascular complications in classical Ehlers-Danlos syndromes
on 15 janvier 2025
BMJ Case Rep. 2025 Jan 4;18(1):e260109. doi: 10.1136/bcr-2024-260109.ABSTRACTEhlers-Danlos syndromes (EDS) are a group of connective tissue disorders associated with skin, ligament, blood vessel and organ abnormalities. Skin hyperextensibility, […]
Analysis of Antroduodenal Motility in Patients With Hypermobility Spectrum Disorders/Hypermobile Ehlers-Danlos Syndrome
on 15 janvier 2025
Aliment Pharmacol Ther. 2025 Jan 2. doi: 10.1111/apt.18471. Online ahead of print.ABSTRACTHypermobility spectrum disorders (HSD) and hypermobility Ehlers-Danlos syndrome (hEDS) are frequently associated with gastrointestinal symptoms, although the […]
Patient and parent knowledge, understanding, and concerns after a new diagnosis of Ehlers Danlos syndrome
on 15 janvier 2025
Orphanet J Rare Dis. 2024 Dec 30;19(1):493. doi: 10.1186/s13023-024-03517-y.ABSTRACTINTRODUCTION: After diagnosis of Ehlers Danlos Syndrome (EDS), it is unclear what information patients and parents need and understand about EDS. The objective of […]
Vascular Ehlers-Danlos syndrome in children: evaluating the importance of diagnosis and follow-up during childhood
on 15 janvier 2025
Eur J Hum Genet. 2024 Dec 27. doi: 10.1038/s41431-024-01773-x. Online ahead of print.ABSTRACTVascular Ehlers-Danlos syndrome (vEDS) is a rare inherited connective tissue disorder predominantly caused by pathogenic COL3A1 variants. Characteristic […]
Vascular Ehlers-Danlos syndrome, a therapeutic challenge
on 15 janvier 2025
Med Clin (Barc). 2024 Dec 26:S0025-7753(24)00711-5. doi: 10.1016/j.medcli.2024.10.027. Online ahead of print.NO ABSTRACTPMID:39730285 | DOI:10.1016/j.medcli.2024.10.027
Navigating AML treatment in vascular Ehlers-Danlos syndrome: achieving deeper remission with oral azacitidine-a first case report
on 15 janvier 2025
Leuk Lymphoma. 2024 Dec 24:1-5. doi: 10.1080/10428194.2024.2438807. Online ahead of print.NO ABSTRACTPMID:39718456 | DOI:10.1080/10428194.2024.2438807

Études cliniques

maladies_complexes_etudes_cliniques via biblio.chum on Inoreader

Methylprednisolone in Patients with Cognitive Deficits in Post-COVID-19 Syndrome (PCS)
on 3 mars 2025
Conditions: Post-COVID-19 Syndrome Interventions: Drug: Methylprednisolone Sponsors: Charite University, Berlin, Germany Recruiting
SENSING-AI in Patients with Long COVID (SENSING-AI)
on 3 mars 2025
Conditions: Post-acute COVID-19 Syndrome Interventions: Other: Review of available clinical data sources related to use cases Sponsors: Adhera Health, Inc.; Hospital Universitario Virgen Macarena Completed
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
on 3 mars 2025
Conditions: Long Haul COVID-19; Post-Acute COVID-19 Syndrome; Anosmia; Olfaction Disorders Interventions: Drug: Sodium Citrate; Drug: Normal Saline; Other: Olfactory Training Kit - "The Olfactory Kit, by AdvancedRx" Sponsors: University of North […]
Incidence, Associated Factors, and Burden of Post COVID-19 Condition in Brazil
on 3 mars 2025
Conditions: Post-Acute COVID-19 Syndrome Interventions: Other: Multiple exposures Sponsors: Inova Medical; Merck Sharp & Dohme LLC Recruiting
Tele-Rehabilitative Exercise Training Program in Nurses with Long COVID
on 3 mars 2025
Conditions: Cardiorespiratory Fitness; Exercise; Long COVID; Nurses; Quality of Life (QOL); Fatigue; Stress; Tele-rehabilitation Interventions: Device: wearable device; Behavioral: Healthy consulation Sponsors: Shang-Lin Chiang Completed
Physical Activity Post COVID-19
on 3 mars 2025
Conditions: Covid19 Interventions: Behavioral: Physical activity Sponsors: University of Alcala; Professional College of Physiotherapists of the Community of Madrid (CPFCM); University Hospital of Guadalajara (HUGU) Completed
CISCO-21 Prevent and Treat Long COVID-19.
on 3 mars 2025
Conditions: Covid19 Interventions: Other: Resistance Exercise Sponsors: NHS Greater Glasgow and Clyde; University of Glasgow; Chief Scientist Office of the Scottish Government Completed
NE3107 in Adults with Long COVID
on 3 mars 2025
Conditions: Long COVID Interventions: Drug: NE3107; Drug: Placebo Sponsors: BioVie Inc. Not yet recruiting
Cognitive-Sensorimotor Function in Long-COVID
on 3 mars 2025
Conditions: Post-acute Sequelae of SARS-CoV-2 Infection Sponsors: VA Office of Research and Development; Edward Hines Jr. VA Hospital Not yet recruiting
Dysbiosis & Long COVID
on 13 février 2025
Conditions: COVID-19 Interventions: Biological: Subjects with and without Long COVID Sponsors: University of Chicago Recruiting
Effectiveness of a Personalized In-home Telerehabilitation Program on Self-Care in Patients with Long COVID: a Randomized Clinical Trial
on 13 février 2025
Conditions: Long COVID Syndrome Interventions: Other: Education for self-management; Other: Personalised exercise program; Other: Usual Care Sponsors: CEU San Pablo University Not yet recruiting
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
on 11 février 2025
Conditions: Post-Acute COVID-19; Post-Acute COVID-19 Syndrome; Post-Acute COVID-19 Infection; Long COVID; Long Covid19; Dyspnea; Orthostasis; Cognitive Impairment Interventions: Other: Comprehensive Rehabilitation; Other: Augmented Usual Care […]
Understanding the Long-term Impact of COVID on Children and Families
on 11 février 2025
Conditions: SARS-CoV-2 Infection Sponsors: NYU Langone Health; National Heart, Lung, and Blood Institute (NHLBI) Active, not recruiting
Basel Long COVID-19 Cohort Study and Digital Long COVID Substudy
on 11 février 2025
Conditions: Post COVID-19 Condition (PCC) Interventions: Other: Digital intervention (DiLCoS); Other: Data collection Sponsors: University Hospital, Basel, Switzerland; State Secretariat for Education Research and Innovation, Switzerland; European […]
REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID
on 11 février 2025
Conditions: Post-COVID-19 Syndrome; Fatigue Syndrome, Chronic Interventions: Other: Anhydrous Enol-Oxaloacetate, a "Medical Food"; Other: White Rice Flour Sponsors: Terra Biological LLC; Bateman Horne Center Completed
SARS-COV-2 VARIANTS' EFFECT ON PREGNANCY AND LONG-TERM OUTCOMES AMONG PREGNANT WOMEN AND THEIR NEWBORNS IN ESTONIA
on 11 février 2025
Conditions: Pregnancy; COVID-19; Post-COVID / Long-COVID; Newborn Health; Miscarriages Interventions: Other: COVID-19 infection Sponsors: University of Tartu Completed
Long-term Effects of COVID-19
on 11 février 2025
Conditions: COVID-19; SAR-CoV-2 Interventions: Drug: (R)-1-(2-chlorophenyl)- N-[11C] ([11C] PK11195); Drug: 2-(4-[11C]methylamino phenyl)-6-hydroxybenzothiazole (11C]6-OH-BTA-1 or [11C]PIB) Sponsors: Mayo Clinic; National Institute of Neurological […]
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
on 11 février 2025
Conditions: Post-Concussion Syndrome; COVID Long-Haul; COVID-19 Interventions: Device: percutaneous electrical nerve-field stimulation, PENFS; Device: percutaneous electrical nerve-field stimulation, PENFS (sham device); Device: percutaneous […]
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID
on 11 février 2025
Conditions: Long COVID Interventions: Drug: Ketamine only Sponsors: University of Texas at Austin; Roots Behavioral Health Not yet recruiting
Biomarkers for Post-COVID Conditions
on 11 février 2025
Conditions: COVID-19; SARS-CoV-2; Biomarkers; Post-acute COVID-19 Syndrome Sponsors: Zealand University Hospital; Mental Health Services in the Capital Region, Denmark; Skane University Hospital Completed

Revue d'actualités

maladies_complexes_actualites via biblio.chum on Inoreader

Chronic fatigue syndrome: Outcry over Cochrane decision to abandon review of exercise therapy
on 3 mars 2025
A decision to cancel a planned update of a Cochrane systematic review of exercise therapy for chronic fatigue syndrome has met with anger from a group advising the review and the patient community.The decision has reignited calls for the review,1 […]
Maladie de Lyme : pourquoi les nouvelles recommandations de la HAS sont-elles controversées ? - Pourquoi Docteur ?
on 3 mars 2025
Maladie de Lyme : pourquoi les nouvelles recommandations de la HAS sont-elles controversées ? Pourquoi Docteur ?
‘We’re losing decades of our life to this illness’: long Covid patients on the fear of being forgotten
on 3 mars 2025
On 20 March 2020, Rowan Brown started to feel a tickle at the back of her throat. Over the next few days, new symptoms began to emerge: difficulty breathing, some tiredness. By the following week, the UK had been put under lockdown in a last-minute […]
Cinq ans de pandémie de COVID-19 en 7 chiffres - Le Devoir
on 3 mars 2025
Cinq ans de pandémie de COVID-19 en 7 chiffres Le Devoir
La COVID longue, toujours une énigme qui fait vivre l’enfer à ses victimes - La Voix de l'Est
on 3 mars 2025
La COVID longue, toujours une énigme qui fait vivre l’enfer à ses victimes La Voix de l'Est
L’odorat se fait parfois jouer des tours par le cerveau - Radio-Canada.ca
on 3 mars 2025
L’odorat se fait parfois jouer des tours par le cerveau Radio-Canada.ca
COVID-19 : tout sur la pandémie | Dossier - Radio-Canada.ca
on 3 mars 2025
COVID-19 : tout sur la pandémie | Dossier Radio-Canada.ca
Atteinte de la COVID longue, Isabelle Desbiens apprend à vivre avec la maladie - Radio-Canada.ca
on 3 mars 2025
Atteinte de la COVID longue, Isabelle Desbiens apprend à vivre avec la maladie Radio-Canada.ca
Prêts à tout pour guérir de la COVID longue - Radio-Canada.ca
on 3 mars 2025
Prêts à tout pour guérir de la COVID longue Radio-Canada.ca
Long COVID impacting more than 1 million children: CDC study suggests
on 11 février 2025
Higher levels of long COVID were found in lower-income households.More than 1 million children may have been affected by long COVID as of 2023, new federal data published Monday suggests.Long COVID, a condition that occurs when patients still have […]
Exeter firm excited over long Covid test breakthrough
on 11 février 2025
Richard GreenBBC News, DevonBBCAttomarker insists the test can help many long Covid patients, should it be rolled out in the future An Exeter-based research firm has developed what it believes is a "world first" breakthrough test to help confirm the […]
En cas de Covid long, 90% des personnes se retrouvent en incapacité de travail totale
on 11 février 2025
Un peu moins de 2% des nouvelles demandes adressées à l'assurance-invalidité (AI) entre 2021 et 2023 concernent des personnes souffrant de Covid long. Cela représente près de 3000 personnes, selon une étude publiée jeudi, la première à […]
Covid long : 2 ans après l'infection, deux tiers des adultes sont encore malades
on 11 février 2025
Le Covid long doit-il à présent être qualifié de maladie chronique à la faible possibilité de guérison ? "Nous le craignons", répond le Pr Winfried Kern, médecin interniste et infectiologue à l'université de Fribourg (Allemagne). Deux […]
Les femmes sont plus à risque de développer un Covid long que les hommes
on 11 février 2025
Par Camille Gaubert le 24.01.2025 à 17h38 Ecouter 3 min. Les femmes ont un risque augmenté de 31% de développer un Covid long par rapport aux hommes, d'après une étude. Une différence qui se creuse encore pour les plus de 40 ans.
Do We Need a Lyme Disease Vaccine?
on 15 janvier 2025
Pediatr Infect Dis J. 2025 Jan 1;44(1):32. doi: 10.1097/INF.0000000000004537. Epub 2024 Oct 7.NO ABSTRACTPMID:39705403 | DOI:10.1097/INF.0000000000004537
Patients With HIV May Have High Prevalence of Long COVID - AJMC.com Managed Markets Network
on 15 janvier 2025
Patients With HIV May Have High Prevalence of Long COVID AJMC.com Managed Markets Network
NIH-funded study finds cases of ME/CFS increase following SARS-CoV-2 - National Institutes of Health
on 15 janvier 2025
NIH-funded study finds cases of ME/CFS increase following SARS-CoV-2 National Institutes of Health
La force du nombre pour affronter la COVID longue - La Tribune
on 15 janvier 2025
La force du nombre pour affronter la COVID longue La Tribune
VIDÉO | Le tiers des tiques sont porteuses de l’anaplasmose transmissible à l’humain - Noovo Info
on 20 Décembre 2024
VIDÉO | Le tiers des tiques sont porteuses de l’anaplasmose transmissible à l’humain Noovo Info
https://healthsci.mcmaster.ca/mcmaster-researchers-find-talk-therapy-rehabilitation-likely-improve-long-covid-symptoms/
on 20 Décembre 2024

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