Description
COVID longue
- Work Productivity Loss in People Living with Long COVID Symptoms over 2 years from Infectionon 8 mai 2025
J Occup Environ Med. 2025 May 5. doi: 10.1097/JOM.0000000000003440. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate the work productivity loss in people experiencing long COVID symptoms more than two years after infection.METHODS: In a […]
- The risk of Long Covid symptoms: a systematic review and meta-analysis of controlled studieson 8 mai 2025
Nat Commun. 2025 May 7;16(1):4249. doi: 10.1038/s41467-025-59012-w.ABSTRACTThe global evidence on the risk of symptoms of Long Covid in general populations infected with SARS-CoV-2 compared to uninfected comparator/control populations remains […]
- Mixed methods study of views and experience of non-hospitalised individuals with long COVID of using pacing interventionson 8 mai 2025
Sci Rep. 2025 Apr 25;15(1):14467. doi: 10.1038/s41598-025-96319-6.ABSTRACTLong COVID is highly prevalent and debilitating, with key symptoms including fatigue, breathlessness, and brain fog. Pacing is an approach to energy conservation used to help […]
- Social determinants of recovery from ongoing symptoms following COVID-19 in two UK longitudinal studies: a prospective cohort studyon 8 mai 2025
BMJ Public Health. 2025 Mar 20;3(1):e001166. doi: 10.1136/bmjph-2024-001166. eCollection 2025 Jan.ABSTRACTINTRODUCTION: Social gradients in COVID-19 exposure and severity have been observed internationally. Whether combinations of pre-existing […]
- Development and Validation of POCOKIDS-Q-A Questionnaire to Assess Post COVID-19 Symptoms in Childrenon 8 mai 2025
Acta Paediatr. 2025 Apr 13. doi: 10.1111/apa.70094. Online ahead of print.ABSTRACTAIM: To identify the symptom burden in children and adolescents with post COVID-19, a validated and reliable instrument is needed, particularly to assess symptoms and […]
- A multidimensional network of factors associated with long COVID in the French populationon 8 mai 2025
Commun Med (Lond). 2025 Apr 13;5(1):114. doi: 10.1038/s43856-025-00846-2.ABSTRACTBACKGROUND: Various factors associated with long COVID have been evidenced, but the heterogeneity of definitions and epidemiological investigations has often hidden […]
- Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health recordson 8 mai 2025
Nat Commun. 2025 Apr 11;16(1):3445. doi: 10.1038/s41467-025-56284-0.ABSTRACTThe risk of cardiovascular outcomes following SARS-CoV-2 infection has been reported in adults, but evidence in children and adolescents is limited. This paper assessed the […]
- Considerations for Long COVID Rehabilitation in Womenon 8 mai 2025
Phys Med Rehabil Clin N Am. 2025 May;36(2):371-387. doi: 10.1016/j.pmr.2024.11.009. Epub 2024 Dec 9.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic has given rise to long COVID, a prolonged manifestation of severe acute respiratory syndrome […]
- Pediatric Long COVID Subphenotypes: An EHR-based study from the RECOVER programon 8 mai 2025
PLOS Digit Health. 2025 Apr 10;4(4):e0000747. doi: 10.1371/journal.pdig.0000747. eCollection 2025 Apr.ABSTRACTPediatric Long COVID has been associated with a wide variety of symptoms, conditions, and organ systems, but distinct clinical […]
- A long COVID researcher continues to search for answers | Harvard T.H. Chan School of Public Healthon 8 mai 2025
Beth Stelson / Photo by Kent Dayton Amid federal funding cuts for health research, the Trump administration has shuttered the Department of Health and Human Services’ (HHS) Office of Long Covid Research and Practice. Beth Stelson, postdoctoral […]
- The risk of Long Covid symptoms: a systematic review and meta-analysis of controlled studies - Natureon 8 mai 2025
The risk of Long Covid symptoms: a systematic review and meta-analysis of controlled studies Nature
- Long COVID-19: Impact of a personalized rehabilitation programon 31 mars 2025
Rehabilitacion (Madr). 2025 Mar 28;59(2):100903. doi: 10.1016/j.rh.2025.100903. Online ahead of print.ABSTRACTINTRODUCTION: Several guidelines have proposed specific rehabilitation programs to treat symptoms/sequelae in patients with post-acute […]
- Reorganization of brain connectivity in post-COVID condition: a (18)F-FDG PET studyon 31 mars 2025
EJNMMI Res. 2025 Mar 30;15(1):28. doi: 10.1186/s13550-025-01217-7.ABSTRACTBACKGROUND: A hypometabolic brain pattern has been reported in patients with post-COVID condition (PCC). The aim of this study was to investigate reorganization in metabolic […]
- Identifying risk factors and predicting long COVID in a Spanish cohorton 31 mars 2025
Sci Rep. 2025 Mar 28;15(1):10758. doi: 10.1038/s41598-025-94765-w.ABSTRACTMany studies have investigated symptoms, comorbidities, demographic factors, and vaccine effects in relation to long COVID (LC-19) across global populations. However, a number […]
- Effectiveness and tolerance of exercise interventions for long COVID: a systematic review of randomised controlled trialson 31 mars 2025
BMJ Open. 2025 Mar 22;15(3):e082441. doi: 10.1136/bmjopen-2023-082441.ABSTRACTOBJECTIVES: To examine the effectiveness of exercise interventions to improve long COVID symptoms and the tolerance of exercise interventions among people with long […]
- Vitamin B12 as an epidrug for regulating peripheral blood biomarkers in long COVID-associated visuoconstructive deficiton 31 mars 2025
Sci Rep. 2025 Mar 19;15(1):9438. doi: 10.1038/s41598-025-86637-0.ABSTRACTApproximately four months after recovering from a mild COVID-19 infection, around 25% of individuals developed visuoconstructive deficit (VCD), which was found to be correlated […]
- Long COVID: emerging pathophysiological mechanismson 31 mars 2025
Minerva Med. 2025 Mar 19. doi: 10.23736/S0026-4806.25.09539-4. Online ahead of print.ABSTRACTPost-COVID conditions, also termed "long COVID," are a heterogeneous set of conditions persisting greater than 28 days after initial infection. These […]
- Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)on 31 mars 2025
Sci Rep. 2025 Mar 18;15(1):9387. doi: 10.1038/s41598-025-93664-4.ABSTRACTThe Post-acute Sequela of SARS-CoV-2 (PASC) syndrome, also known as Long-COVID, often presents with subjective symptoms such as brain fog and cognitive fatigue. Increased […]
- Socioeconomic disparities in long COVID diagnosis among ethnic minorities in Denmarkon 31 mars 2025
Soc Sci Med. 2025 Mar 10;372:117944. doi: 10.1016/j.socscimed.2025.117944. Online ahead of print.ABSTRACTBACKGROUND: Low socioeconomic status has been demonstrated as a risk factor for COVID-19 severity and mortality. However, whether socioeconomic […]
- Spatial transcriptomics of the epipharynx in long COVID identifies SARS-CoV-2 signalling pathways and the therapeutic potential of epipharyngeal abrasive therapyon 31 mars 2025
Sci Rep. 2025 Mar 12;15(1):8618. doi: 10.1038/s41598-025-92908-7.ABSTRACTIn this study, the critical role of the epipharynx in managing long-term coronavirus disease 2019 (COVID-19), and in particular, how residual SARS-CoV-2 RNA affects signalling […]
COVID longue : lignes directrices canadiennes
Mise à jour du 5 mars 2025
Mise à jour du 31 mars 2025
Maladie de Lyme
- Computerised decision support system towards informing Lyme borreliosis incidence in Franceon 8 mai 2025
Sci Rep. 2025 May 3;15(1):15506. doi: 10.1038/s41598-025-99896-8.ABSTRACTIn Europe, the estimation of Lyme borreliosis (LB) incidence is challenged by its heterogeneous reporting. In France, LB incidence is estimated from cases reported voluntarily […]
- FACE DROPS: A Clinical Risk Assessment Tool for Differentiation of Acute Lyme Disease-Associated Facial Palsy From Bell Palsyon 8 mai 2025
Neurol Clin Pract. 2025 Jun;15(3):e200476. doi: 10.1212/CPJ.0000000000200476. Epub 2025 Apr 18.ABSTRACTBACKGROUND AND OBJECTIVES: Facial palsy is a common manifestation of Lyme disease, accounting for up to 5% of acute facial palsies in endemic […]
- Alpha-Gal Sensitization Dynamics in Individuals After Tick Bites With or Without Erythema Migranson 8 mai 2025
Clin Exp Allergy. 2025 Apr;55(4):350-353. doi: 10.1111/cea.70011. Epub 2025 Mar 19.ABSTRACTα-Gal syndrome (AGS) is an emerging tick-borne disease characterised by the development of specific immunoglobulin E (sIgE) antibodies against […]
- Confusing variety of symptoms: Lyme carditis coinciding with Puumala hantavirus infectionon 31 mars 2025
Diagn Microbiol Infect Dis. 2025 Jun;112(2):116784. doi: 10.1016/j.diagmicrobio.2025.116784. Epub 2025 Mar 1.ABSTRACTThe temporal coincidence of a tick- and rodent-associated disease led to a confusing variety of symptoms, which posed diagnostic […]
- Lower Frequency of Multiple Erythema Migrans Skin Lesions in Lyme Reinfections, Europeon 31 mars 2025
Emerg Infect Dis. 2025 Apr;31(4):662-668. doi: 10.3201/eid3104.241329.ABSTRACTThe erythema migrans (EM) skin lesion is the most common clinical manifestation of Lyme borreliosis. Information about EM in Lyme borreliosis reinfection is limited. Of […]
- UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosison 31 mars 2025
Sci Rep. 2025 Mar 11;15(1):8442. doi: 10.1038/s41598-025-92189-0.ABSTRACTThe diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient's cerebrospinal fluid (CSF), which involves […]
- Adult-Onset Still's Disease (AOSD) in Patient with Previous Lyme Diseaseon 31 mars 2025
J Brown Hosp Med. 2025 Jan 1;4(1):16-19. doi: 10.56305/001c.124992. eCollection 2025.ABSTRACTAdult-onset Still's Disease (AOSD) is a rare autoimmune disorder causing systemic inflammation that presents with a rash, fever, polyarthritis, and a […]
- Borrelia spielmanii-Associated Neuroborreliosis in Patient Receiving Rituximab, Belgiumon 3 mars 2025
Emerg Infect Dis. 2025 Feb;31(2):341-344. doi: 10.3201/eid3102.240777.ABSTRACTA 58-year-old woman in Belgium with a history of follicular lymphoma treated with rituximab sought care for a rapid sensory-motor deficit. Seronegative neuroborreliosis […]
- Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivityon 3 mars 2025
Commun Biol. 2025 Mar 1;8(1):341. doi: 10.1038/s42003-025-07781-x.ABSTRACTHigh-temperature requirement protease A (HtrA) is a family of serine proteases that regulate bacterial stress response through controlling protein quality. This report shows […]
- A type-specific B-cell epitope at the apex of outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferion 3 mars 2025
Microbiol Spectr. 2025 Feb 14:e0288324. doi: 10.1128/spectrum.02883-24. Online ahead of print.ABSTRACTBroadly protective immunity to the Lyme disease spirochete, Borreliella burgdorferi, is constrained by antibodies against type-specific epitopes on […]
- Borréliose de Lyme et autres maladies vectorielles à tiques : la HAS actualise ses recommandations - Haute Autorité de Santéon 3 mars 2025
Borréliose de Lyme et autres maladies vectorielles à tiques : la HAS actualise ses recommandations Haute Autorité de Santé
- Dose Evaluation and Optimization of Amoxicillin in Children Treated for Lyme Diseaseon 13 février 2025
J Clin Pharmacol. 2025 Jan 27. doi: 10.1002/jcph.6190. Online ahead of print.ABSTRACTAmoxicillin is commonly used to treat erythema migrans in the first stage of Lyme disease in children, with a recommended dose of 50 mg/kg/day, administered three […]
- Lyme disease associated neurological and musculoskeletal symptoms: A systematic review and meta-analysison 13 février 2025
Brain Behav Immun Health. 2025 Jan 2;43:100931. doi: 10.1016/j.bbih.2024.100931. eCollection 2025 Feb.ABSTRACTBACKGROUND AND OBJECTIVE: Lyme disease, caused by Borrelia burgdorferi, presents major health challenges worldwide, leading to serious […]
- Lyme neuroborreliosis in Japan: Borrelia burgdorferi sensu lato as a cause of meningitis of previously undetermined etiology in hospitalized patients outside of the island of Hokkaido, 2010-2021on 15 janvier 2025
Eur J Neurol. 2025 Jan;32(1):e70005. doi: 10.1111/ene.70005.ABSTRACTBACKGROUND AND PURPOSE: Clinical manifestations of Lyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato (Bbsl), include erythema migrans, Lyme neuroborreliosis (LNB), […]
- Perspective: Incidence of Clinician-Diagnosed Lyme Disease in Manitoba, Canada 2009-2018on 15 janvier 2025
Vector Borne Zoonotic Dis. 2025 Jan 6. doi: 10.1089/vbz.2024.0088. Online ahead of print.ABSTRACTIntroduction: Lyme disease (LD) surveillance yields useful information to monitor the disease trends and spatial distribution. However, due to several […]
- Clinical characteristics and serological profiles of Lyme disease in children: a 15-year retrospective cohort study in Switzerlandon 15 janvier 2025
Lancet Reg Health Eur. 2024 Dec 9;48:101143. doi: 10.1016/j.lanepe.2024.101143. eCollection 2025 Jan.ABSTRACTBACKGROUND: Lyme disease (LD) is caused by Borrelia burgdorferi and is the most common tickborne disease in the northern hemisphere. […]
- The Current and Future State of Vaccines for Lyme Diseaseon 15 janvier 2025
Clin Infect Dis. 2024 Dec 23:ciae639. doi: 10.1093/cid/ciae639. Online ahead of print.ABSTRACTLyme disease is caused by Borrelia species that are transmitted by Ixodes ticks prevalent in parts of the United States and Europe. A Lyme vaccine […]
- bb0689 contributes to the virulence of Borrelia burgdorferi in a murine model of Lyme diseaseon 20 Décembre 2024
Infect Immun. 2024 Dec 16:e0045924. doi: 10.1128/iai.00459-24. Online ahead of print.ABSTRACTBorrelia burgdorferi, the Lyme disease pathogen, continuously changes its gene expression profile in order to adapt to ticks and mammalian hosts. The […]
- Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in miceon 20 Décembre 2024
Nat Commun. 2024 Nov 29;15(1):10417. doi: 10.1038/s41467-024-54806-w.ABSTRACTFlagella propel pathogens through their environments, yet are expensive to synthesize and are immunogenic. Thus, complex hierarchical regulatory networks control flagellar […]
- Anti-RA33 Antibodies Are Present in Patients With Lyme Diseaseon 20 Décembre 2024
J Clin Rheumatol. 2024 Nov 22. doi: 10.1097/RHU.0000000000002176. Online ahead of print.ABSTRACTBACKGROUND/OBJECTIVE: To determine if anti-RA33 antibodies, which can be seen in early forms of inflammatory arthritis, are present in patients with Lyme […]
Encéphalomyélite myalgique
- Unequal access to diagnosis of myalgic encephalomyelitis in Englandon 8 mai 2025
BMC Public Health. 2025 Apr 22;25(1):1417. doi: 10.1186/s12889-025-22603-9.ABSTRACTBACKGROUND: People with Myalgic Encephalomyelitis (ME/CFS; sometimes referred to as chronic fatigue syndrome) experience poor health-related quality of life and only […]
- Autoantibody targeting therapies in post COVID syndrome and myalgic encephalomyelitis/chronic fatigue syndromeon 8 mai 2025
Expert Opin Biol Ther. 2025 Apr 10. doi: 10.1080/14712598.2025.2492774. Online ahead of print.NO ABSTRACTPMID:40211686 | DOI:10.1080/14712598.2025.2492774
- PKM2 accelerated the progression of chronic fatigue syndrome via promoting the H4K12la/ NF-kappaB induced neuroinflammation and mitochondrial damageon 31 mars 2025
Sci Rep. 2025 Mar 28;15(1):10772. doi: 10.1038/s41598-025-93313-w.ABSTRACTThis study aims to explore the effects and potential mechanisms of PKM2-mediated neuroinflammation leading to mitochondrial damage and its role in the progression of chronic […]
- A research perspective on sphingolipid metabolism and myalgic encephalomyelitis/chronic fatigue syndromeon 31 mars 2025
Neural Regen Res. 2025 Mar 25. doi: 10.4103/NRR.NRR-D-24-01506. Online ahead of print.NO ABSTRACTPMID:40145965 | DOI:10.4103/NRR.NRR-D-24-01506
- Improving myalgic encephalomyelitis population sampling: Applying an online respondent-driven method to address biases in G93.3 register dataon 31 mars 2025
J Health Psychol. 2025 Mar 24:13591053251325690. doi: 10.1177/13591053251325690. Online ahead of print.ABSTRACTWith widespread late- and under-diagnosing, health register code G93.3 data cannot offer an unbiased sampling frame for myalgic […]
- Voice of the patient: people with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) share in their own wordson 31 mars 2025
Fatigue. 2025;13(2):1-11. doi: 10.1080/21641846.2024.2444826.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, debilitating illness affecting millions of people worldwide. Patients with ME/CFS often feel […]
- Assessing fatigue in myalgic encephalomyelitis/chronic fatigue syndrome patients before and after treatment with bright light therapy: A prospective randomized controlled crossover studyon 31 mars 2025
Sleep Med. 2025 Mar 14;129:369-374. doi: 10.1016/j.sleep.2025.03.003. Online ahead of print.ABSTRACTOBJECTIVE: The aim of the current study was to test the effectiveness of treatment with bright light therapy (BLT) on fatigue and cognitive function […]
- Under-Served Groups and Myalgic Encephalomyelitis Research Workshop; Multiple Barriers to Effective Healthcare, Research and Public Participationon 31 mars 2025
Health Expect. 2025 Apr;28(2):e70214. doi: 10.1111/hex.70214.ABSTRACTPublic involvement in research and other initiatives for myalgic encephalomyelitis (ME) (also known as chronic fatigue syndrome) has been crucial in raising awareness of the […]
- Post-infective myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID as two puzzling faces of the same medal. Recent insightson 31 mars 2025
Int Immunopharmacol. 2025 Mar 7:114365. doi: 10.1016/j.intimp.2025.114365. Online ahead of print.NO ABSTRACTPMID:40057420 | DOI:10.1016/j.intimp.2025.114365
- Mapping the Complexity of ME/CFS: Evidence for Abnormal Energy Metabolism, Altered Immune Profile and Vascular Dysfunctionon 3 mars 2025
Author Names: Heng R.B.,Gunasegaran B.,Krishnamurthy S.,Bustamante S.,Pires A.S.,Chow S.,Ahn S.B.,Paul-Heng M.,Maciver Y.,Smith K.,Tran D.P.,Howley P.P.,Bilgin A.A.,Sharland A.,Schloeffel R.,Guillemin G.J. Database Source: […]
- Chronic Fatigue Syndrome: Pulling Back the Curtainson 3 mars 2025
Author Names: anonymous Database Source: Embase Daily Updates Journal Title: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Article […]
- A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis - chronic fatigue syndromeon 3 mars 2025
Author Names: Hirsch A.G.,Justice A.E.,Poissant A.,Nordberg C.M.,Josyula N.S.,Aucott J.,Rebman A.W.,Schwartz B.S. Database Source: Embase Daily Updates Journal Title: BMC Infectious Diseases […]
- Cerebrospinal fluid metabolomics, lipidomics and serine pathway dysfunction in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS)on 3 mars 2025
Sci Rep. 2025 Mar 3;15(1):7381. doi: 10.1038/s41598-025-91324-1.ABSTRACTWe proposed that cerebrospinal fluid would provide objective evidence for disrupted brain metabolism in myalgic encephalomyelitis/chronic fatigue syndroome (ME/CFS). The concept […]
- A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis - chronic fatigue syndromeon 3 mars 2025
BMC Infect Dis. 2025 Feb 24;25(1):265. doi: 10.1186/s12879-024-10238-x.ABSTRACTBACKGROUND: Up to 20% of Lyme disease cases experience post-treatment Lyme disease syndrome (PTLDS). The biological basis for PTLDS is poorly understood and no […]
- Managing Energy, and Shaping Care: Insights from Adults with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Through Co-Production Workshopson 3 mars 2025
Am J Med. 2025 Feb 15:S0002-9343(25)00093-2. doi: 10.1016/j.amjmed.2025.02.008. Online ahead of print.ABSTRACTBACKGROUND: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, debilitating condition characterised by severe […]
- Cognitive functioning in patients with chronic fatigue syndrome: Slowed information processing or a deficit in attentional selectivity?on 3 mars 2025
Neuropsychology. 2025 Feb;39(2):152-161. doi: 10.1037/neu0000982.ABSTRACTOBJECTIVE: By addressing numerous statistical, theoretical, and methodological weaknesses of existing research on chronic fatigue syndrome (CFS), this study attempted to […]
- Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndromeon 11 février 2025
medRxiv [Preprint]. 2025 Jan 6:2025.01.02.24319359. doi: 10.1101/2025.01.02.24319359.ABSTRACTMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating but poorly-understood disease. ME/CFS symptoms can range from mild to severe, […]
- Provocation of brachial plexus and systemic symptoms during the elevated arm stress test in individuals with myalgic encephalomyelitis/chronic fatigue syndrome or idiopathic chronic fatigueon 11 février 2025
J Transl Med. 2025 Jan 22;23(1):106. doi: 10.1186/s12967-025-06137-7.ABSTRACTBACKGROUND: We have noted that some adolescents and young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) report difficulty with arms-overhead […]
- The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiologyon 11 février 2025
J Transl Med. 2025 Feb 4;23(1):149. doi: 10.1186/s12967-025-06146-6.ABSTRACTBACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease of unknown aetiology characterised by symptoms of post-exertional malaise (PEM) and […]
- Chronic Fatigue Syndrome: Pulling Back the Curtainson 11 février 2025
Neuroscientist. 2025 Feb;31(1):5. doi: 10.1177/10738584241308723.NO ABSTRACTPMID:39927439 | DOI:10.1177/10738584241308723
Syndrome d'Ehlers-Danlos
- The Complexities of Navigating the Healthcare System as an Autistic Individual with Ehlers-Danlos Syndrome: A Patient Perspectiveon 8 mai 2025
J Patient Exp. 2025 Apr 15;12:23743735251333601. doi: 10.1177/23743735251333601. eCollection 2025.ABSTRACTAutistic individuals with hypermobile Ehlers-Danlos syndrome (hEDS) often face unique challenges navigating healthcare systems due to lack of […]
- Whole Blood Multi-OMIC Analysis Is Effective in Clinical Interpretation of Splicing Aberrations in PLOD1-Related Kyphoscoliotic Ehlers-Danlos Syndromeon 8 mai 2025
Am J Med Genet A. 2025 Apr 10:e64085. doi: 10.1002/ajmg.a.64085. Online ahead of print.ABSTRACTKyphoscoliotic Ehlers-Danlos syndrome (kEDS) Type 1 is a rare hereditary connective tissue disorder due to biallelic deleterious variants in PLOD1 and is […]
- HOPE for Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorder (HSD)-A Pilot Randomised Controlled Trial of Feasibility, Acceptability and Appropriatenesson 8 mai 2025
Eur J Pain. 2025 Jul;29(6):e70030. doi: 10.1002/ejp.70030.ABSTRACTBACKGROUND: Feasibility and effectiveness of online pain management programs for chronic widespread pain conditions have been shown; yet, there are no empirically evaluated programs […]
- Seventeen-year outcome of surgical management of severe early onset kyphoscoliosis in a patient with arthrochalasia-type Ehlers-Danloson 8 mai 2025
Spine Deform. 2025 Apr 14. doi: 10.1007/s43390-025-01071-6. Online ahead of print.ABSTRACTWe report on the surgical management of severe early onset kyphoscoliosis in a 5-year-old patient with the rare arthrochalasia subtype of Ehlers-Danlos […]
- Autism in the context of joint hypermobility, hypermobility spectrum disorders, and Ehlers-Danlos syndromes: A systematic review and prevalence meta-analyseson 31 mars 2025
Autism. 2025 Mar 27:13623613251328059. doi: 10.1177/13623613251328059. Online ahead of print.ABSTRACTIncreasing research suggests a link between autism spectrum disorders and joint hypermobility, hypermobility spectrum disorders, and Ehlers-Danlos […]
- Prevalence of psychiatric and sleep disorders and their impact on quality of life in children with hypermobile Ehlers-Danlos syndrome: an observational studyon 31 mars 2025
Rheumatol Int. 2025 Mar 25;45(4):81. doi: 10.1007/s00296-025-05836-0.ABSTRACTHypermobile Ehlers-Danlos Syndrome (hEDS) is the most common connective tissue disorder. However, few studies exist on psychiatric and sleep disorders in pediatric patients […]
- Pregnancy and Delivery Outcomes in Vascular Ehlers-Danlos Syndrome: A Retrospective Multicentre Cohort Studyon 31 mars 2025
BJOG. 2025 Mar 19. doi: 10.1111/1471-0528.18142. Online ahead of print.ABSTRACTOBJECTIVE: We aim to increase knowledge on pregnancy and delivery risks in vascular Ehlers-Danlos Syndrome (vEDS). Our outcomes can contribute to establishing future […]
- Shaping the future of care for patients with Ehlers-Danlos syndromes: from multidisciplinary management to precision medicineon 31 mars 2025
Orphanet J Rare Dis. 2025 Mar 3;20(1):98. doi: 10.1186/s13023-025-03615-5.NO ABSTRACTPMID:40033344 | DOI:10.1186/s13023-025-03615-5
- Radiographic identification of visceroptosis in hypermobile Ehlers-Danlos syndrome patients with functional gastrointestinal symptoms compared to healthy subjectson 31 mars 2025
Clin Transl Gastroenterol. 2025 Mar 3. doi: 10.14309/ctg.0000000000000834. Online ahead of print.ABSTRACTINTRODUCTION: Visceroptosis is a potential cause of gastrointestinal symptoms in hypermobile Ehlers-Danlos syndrome (hEDS).METHODS: We […]
- Recurrent perforation of an implantable cardioverter-defibrillator lead in a patient with vascular Ehlers-Danlos syndromeon 3 mars 2025
HeartRhythm Case Rep. 2024 Oct 18;11(2):101-103. doi: 10.1016/j.hrcr.2024.10.015. eCollection 2025 Feb.NO ABSTRACTPMID:40018318 | PMC:PMC11862159 | DOI:10.1016/j.hrcr.2024.10.015
- Navigating HOPE (Hypermobile Online Pain managemEnt): Perspectives and Experiences From People With Hypermobile Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder on a Condition-Specific Online Pain Management Programmeon 3 mars 2025
Health Expect. 2025 Feb;28(1):e70186. doi: 10.1111/hex.70186.ABSTRACTINTRODUCTION: The Hypermobile Online Pain managemEnt (HOPE) programme is a stakeholder informed intervention adopting the biopsychosocial pain approach, specifically for people […]
- Rates of mental health concerns among individuals assessed at the GoodHope Ehlers-Danlos Syndrome Clinicon 3 mars 2025
Orphanet J Rare Dis. 2025 Feb 14;20(1):75. doi: 10.1186/s13023-025-03550-5.ABSTRACTPast research has indicated that individuals with Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobililty Spectrum Disorder (G-HSD) report psychological and […]
- Regulation of Joint Tissues and Joint Function: Is There Potential for Lessons to Be Learned Regarding Regulatory Control from Joint Hypermobility Syndromes?on 13 février 2025
Int J Mol Sci. 2025 Jan 31;26(3):1256. doi: 10.3390/ijms26031256.ABSTRACTNormal development of joints starts in utero with the establishment of a cellular and extracellular matrix template. Following birth, individual joint tissues grow and mature […]
- The Impact of Pain on Everyday Activities of People With Hypermobility Spectrum Disorders or Hypermobility Ehlers Danlos Syndromeon 13 février 2025
Eur J Pain. 2025 Mar;29(3):e70000. doi: 10.1002/ejp.70000.ABSTRACTBACKGROUND: This study describes aspects of pain and how pain affects everyday life and examines the relation between chronic pain and activity limitations in people with […]
- Efficacy of Irbesartan in Celiprolol-Treated Patients With Vascular Ehlers-Danlos Syndromeon 13 février 2025
Circulation. 2025 Feb 5. doi: 10.1161/CIRCULATIONAHA.124.072849. Online ahead of print.ABSTRACTBACKGROUND: Vascular Ehlers-Danlos syndrome is a rare genetic disorder characterized by defective type III collagen and a high risk of arterial morbidity […]
- Pediatrics. Diagnosis of generalized joint hypermobility in childrenon 13 février 2025
Rev Med Suisse. 2025 Jan 29;21(903):200-204. doi: 10.53738/REVMED.2025.21.903.200.ABSTRACTJoint hypermobility is a common feature in children and adolescents, often physiological and benign, but it is also a manifestation of hereditary connective […]
- The prevalence of hypermobile Ehlers-Danlos syndrome at a gender-affirming primary care clinicon 13 février 2025
SAGE Open Med. 2025 Jan 22;13:20503121251315021. doi: 10.1177/20503121251315021. eCollection 2025.ABSTRACTOBJECTIVE: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that […]
- Outcomes of Total Joint Arthroplasty in Patients Who Have Ehlers-Danlos Syndrome: A Systematic Review and Meta-Analysison 13 février 2025
J Arthroplasty. 2025 Jan 20:S0883-5403(25)00033-6. doi: 10.1016/j.arth.2025.01.018. Online ahead of print.ABSTRACTBACKGROUND: Patients who have Ehlers-Danlos Syndrome (EDS), a group of connective tissue disorders characterized by aberrant collagen […]
- Trends in surgical procedures for shoulder instability among patients with Ehlers-Danlos syndrome or joint hypermobility syndromeon 13 février 2025
JSES Int. 2024 Aug 27;8(6):1164-1168. doi: 10.1016/j.jseint.2024.08.178. eCollection 2024 Nov.ABSTRACTBACKGROUND: Joint hypermobility syndrome (JHS) and Ehlers-Danlos Syndrome (EDS) are connective tissue disorders characterized by increased joint […]
- Tenascin-X deficiency causing classical-like Ehlers Danlos syndrome type 1 in humans is a significant risk factor for GI and tracheal ruptureson 15 janvier 2025
Clin Transl Gastroenterol. 2025 Jan 14. doi: 10.14309/ctg.0000000000000821. Online ahead of print.ABSTRACTBACKGROUND: Classical-like Ehlers Danlos Syndrome type 1 (clEDS1) is a very rare form of Ehlers Danlos Syndrome (EDS) caused by tenascin-X […]
Études cliniques
- Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.on 8 mai 2025
Conditions: Long Covid-19; Emotional Disorder; Anxiety; Depression Disorders; Emotion Regulation Interventions: Behavioral: Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders; Other: Treatment as Usual (TAU) Sponsors: […]
- Effect of Hi-OxSR for the Treatment of Post COVID Condition (RECLAIM-HiOxSR)on 8 mai 2025
Conditions: Long COVID; Post COVID-19 Condition; Post Acute Sequelae of COVID-19 Interventions: Device: Hi-OxSR device; Device: Hi-Ox device Sponsors: University Health Network, Toronto Not yet recruiting
- Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Studyon 8 mai 2025
Conditions: Long COVID Interventions: Drug: Pirfenidone; Drug: Placebo for pirfenidone; Drug: Upadacitinib; Drug: Placebo for upadacitinib Sponsors: Douglas D. Fraser Not yet recruiting
- Heat thErapy And mobiLity in COVID-19 Survivorson 8 mai 2025
Conditions: Long COVID Interventions: Behavioral: Heat therapy; Behavioral: Sham Control; Behavioral: Walking Sponsors: University of Nebraska; National Institute on Aging (NIA) Not yet recruiting
- Assessing Safety of Coronavirus Infection (COVID-19) Messenger RNA (mRNA) Vaccine Administration in the Setting of a Previous Adverse Reactionon 8 mai 2025
Conditions: COVID-19; Corona Virus Infection Interventions: Biological: Pfizer-BioNTech mRNA COVID-19 vaccine Sponsors: University of Michigan; The Wallace Foundation Completed
- Amantadine Therapy for Cognitive Impairment in Long COVIDon 8 mai 2025
Conditions: Long COVID; Post-COVID19 Condition; Post-Acute COVID19 Syndrome Interventions: Drug: Amantadine Sponsors: Ohio State University Recruiting
- Feasibility of an Augmented Two-Day Step Test and Causal Modeling for Post-Exertional Symptom Exacerbation in Post Covid-19 Syndromeon 8 mai 2025
Conditions: Long COVID Interventions: Device: Portable mask for respiratory gas analysis; Device: Cardio-pulmonary exercise test Sponsors: Universitair Ziekenhuis Brussel; Vrije Universiteit Brussel, Jette, Belgium Recruiting
- Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)on 8 mai 2025
Conditions: Smell Dysfunction; Olfactory Disorder; Long COVID Interventions: Device: Trigeminal Nerve Stimulation (TNS); Other: Active Smell Training (ST); Other: Placebo Smell Training (PBO) Sponsors: Medical University of South Carolina; […]
- Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulationon 8 mai 2025
Conditions: Long COVID; Long COVID Syndrome; Long COVID-19 Syndrome; PASC; PASC Post Acute Sequelae of COVID 19 Interventions: Device: accelerated intermittent theta burst stimulation Sponsors: University of New Mexico; The Mind Research Network; […]
- Mind-Body in Long COVID and Myalgic Encephalomyelitis Study (MILES): A Patient-Centred RCTon 8 mai 2025
Conditions: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Interventions: Other: Dynamic neural retraining system Sponsors: University of Alberta; College of Physicians and Surgeons of Alberta Not yet recruiting
- A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelaeon 8 mai 2025
Conditions: COVID-19 Interventions: Procedure: Bronchoscopies and Bronchoalveolar Lavages (BALs); Diagnostic Test: Chest Tomography (CT); Diagnostic Test: Electrocardiogram (ECG); Diagnostic Test: Pulmonary function tests (PFTs); Diagnostic Test: 6 […]
- The Effect of Smart Sensor Combined With APP for Individualized Precise Exercise Training in Long Covid-19on 8 mai 2025
Conditions: Coronavirus Disease; COVID-19; Long Covid-19; Telerehabilitation Interventions: Device: KNEESUP smart knee assistive device + KNEESUP care APP; Behavioral: Healthy consulation Sponsors: Shang-Lin Chiang Completed
- Feasibility and Preliminary Efficacy of a Group-based Telerehabilitation Program in People With Post-COVID-19 Sequelae (TEPCO).on 8 mai 2025
Conditions: Long COVID-19 Syndrome; Long COVID; Long COVID Syndrome Interventions: Other: Rehabilitation program Sponsors: Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec Completed
- PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)on 8 mai 2025
Conditions: Long COVID; Post Acute Sequelae of COVID-19 Interventions: Drug: 11C-PS13 Sponsors: National Institute of Mental Health (NIMH) Recruiting
- The Roles of Vitamin D and Microbiome in Children With Post-acute COVID-19 Syndromes (PACS) and Long COVIDon 8 mai 2025
Conditions: Post-acute COVID-19 Syndromes Interventions: Other: Vitamin D; Other: Placebo Sponsors: China Medical University Hospital Completed
- Statin TReatment for COVID-19 to Optimise NeuroloGical recovERyon 8 mai 2025
Conditions: Neurocognitive Impairment, Mild Interventions: Drug: Atorvastatin; Other: Standard Care Sponsors: The George Institute; University of Sydney; Monash University; The Alfred; Universidad del Desarrollo; Chinese University of Hong Kong; […]
- Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veteranson 8 mai 2025
Conditions: Neuro-PASC; Long COVID Sponsors: VA Office of Research and Development; James H. Quillen Department of Veterans Affairs Medical Center Recruiting
- Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19on 8 mai 2025
Conditions: Long COVID-19 Interventions: Drug: Low-dose sirolimus; Drug: Placebo Sponsors: Icahn School of Medicine at Mount Sinai; PolyBio Research Foundation; The Anlyan Center Not yet recruiting
- Characteristics of Long COVID-19 Syndromeon 31 mars 2025
Conditions: Long COVID Syndrome Interventions: Other: No intervention Sponsors: Christian Clarenbach Active, not recruiting
- Sequelae of Sars-CoV-2 Infectionson 31 mars 2025
Conditions: Lung Diseases; Cardiac Disease; Inflammatory Reaction Sponsors: University of Giessen Recruiting
Revue d'actualités
- Covid long : réintégration et soutien pratique sur le lieu de travailon 8 mai 2025
L’EU-OSHA publie quelques nouveaux documents contenant des informations et des conseils sur la manière d’aider les travailleurs touchés par un Covid long, soulignant également l’importance de la réintégration et de l’accompagnement dans […]
- Discovery explains Long COVID breathing problems - EurekAlert!on 8 mai 2025
Discovery explains Long COVID breathing problems EurekAlert!
- Long COVID May Cause Long-Term Changes in the Heart and Lungs and May Lead to Cardiac and Pulmonary Diseases - Mount Sinaion 8 mai 2025
Long COVID May Cause Long-Term Changes in the Heart and Lungs and May Lead to Cardiac and Pulmonary Diseases Mount Sinai
- Long Covid is neither psychological nor physical - ScienceNorwayon 8 mai 2025
Long Covid is neither psychological nor physical ScienceNorway
- Beyond long COVID — how reinfections could be causing silent long-term organ damage - CBC.caon 31 mars 2025
Beyond long COVID — how reinfections could be causing silent long-term organ damage CBC.ca
- COVID longue : des manifestants veulent davantage de recherche - Radio-Canadaon 31 mars 2025
COVID longue : des manifestants veulent davantage de recherche Radio-Canada
- Les dés pipés de la COVID longue - Le Soleilon 31 mars 2025
Les dés pipés de la COVID longue Le Soleil
- Quand la guerre contre la COVID longue se livre à trois - Radio-Canadaon 31 mars 2025
Quand la guerre contre la COVID longue se livre à trois Radio-Canada
- Un sportif de 19 ans passe maintenant ses journées alité à cause de la COVID longue durée - Le Journal de Montréalon 31 mars 2025
Un sportif de 19 ans passe maintenant ses journées alité à cause de la COVID longue durée Le Journal de Montréal
- La COVID longue, un pénible héritage de la pandémie - Radio-Canadaon 31 mars 2025
La COVID longue, un pénible héritage de la pandémie Radio-Canada
- COVID longue : « J’ai appris à vivre avec la maladie » - Radio-Canadaon 31 mars 2025
COVID longue : « J’ai appris à vivre avec la maladie » Radio-Canada
- Encore une centaine de nouveaux cas de COVID longue durée chaque mois - Le Journal de Montréalon 31 mars 2025
Encore une centaine de nouveaux cas de COVID longue durée chaque mois Le Journal de Montréal
- La COVID longue, « est-ce que ça va être ça pour le reste de ma vie? » - Radio-Canadaon 31 mars 2025
La COVID longue, « est-ce que ça va être ça pour le reste de ma vie? » Radio-Canada
- Dossier | La COVID-19, cinq ans plus tard | L’espoir au bout de la COVID longue (3 articles) - La Presseon 31 mars 2025
Dossier | La COVID-19, cinq ans plus tard | L’espoir au bout de la COVID longue (3 articles) La Presse
- 5 ans après son apparition en Alberta, la COVID-19 continue de tuer - Radio-Canada.caon 31 mars 2025
5 ans après son apparition en Alberta, la COVID-19 continue de tuer Radio-Canada.ca
- Santé. Maladie de Lyme : retour de la controverse médicale après de nouvelles recommandations de la HAS - Le Bien Publicon 31 mars 2025
Santé. Maladie de Lyme : retour de la controverse médicale après de nouvelles recommandations de la HAS Le Bien Public
- Chronic fatigue syndrome: Outcry over Cochrane decision to abandon review of exercise therapyon 3 mars 2025
A decision to cancel a planned update of a Cochrane systematic review of exercise therapy for chronic fatigue syndrome has met with anger from a group advising the review and the patient community.The decision has reignited calls for the review,1 […]
- Maladie de Lyme : pourquoi les nouvelles recommandations de la HAS sont-elles controversées ? - Pourquoi Docteur ?on 3 mars 2025
Maladie de Lyme : pourquoi les nouvelles recommandations de la HAS sont-elles controversées ? Pourquoi Docteur ?
- ‘We’re losing decades of our life to this illness’: long Covid patients on the fear of being forgottenon 3 mars 2025
On 20 March 2020, Rowan Brown started to feel a tickle at the back of her throat. Over the next few days, new symptoms began to emerge: difficulty breathing, some tiredness. By the following week, the UK had been put under lockdown in a last-minute […]
- Cinq ans de pandémie de COVID-19 en 7 chiffres - Le Devoiron 3 mars 2025
Cinq ans de pandémie de COVID-19 en 7 chiffres Le Devoir
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