Description
Parkinson et parkinsonismes
- Most Parkinson’s Diagnoses Occur After Age 70, with a Slight Rise in Diagnosis Age Since 2017on 27 août 2026
Dual-Team StudyTeam A:Kersten Bartelt, RN|Nicholas VolkerTeam B:Blaine Franklin, PT, DPT|Eric Barkley Among patients newly diagnosed with Parkinson’s disease, 90.2% were aged 60 or older at […]
- Comparative Bibliometric Analysis of Chinese and English Articles on Freezing of Gait in Parkinson's Diseaseon 26 août 2026
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2026 Jun;48(3):498-509. doi: 10.3881/j.issn.1000-503X.16937.ABSTRACTObjective To compare research hotspots and development trends regarding freezing of gait in […]
- Real-world gait changes preceding Parkinson's disease diagnosis in a population-scale UK biobank cohorton 26 août 2026
J Neural Transm (Vienna). 2026 Aug 8. doi: 10.1007/s00702-026-03256-3. Online ahead of print.ABSTRACTParkinson's disease (PD) has a long prodromal phase characterised by non-motor symptoms and subtle […]
- Efficacy and Safety of Electroconvulsive Therapy for Dementia With Lewy Bodies, Its Prodromal Phase, and Parkinson's Disease Dementia: Eight Cases Encountered at Our Institutionon 26 août 2026
Psychogeriatrics. 2026 Sep;26(5):e70204. doi: 10.1111/psyg.70204.ABSTRACTPURPOSE: This study aimed to assess the efficacy and safety of electroconvulsive therapy (ECT) for treating psychiatric […]
- Differences in gait and prefrontal cortical activity between recurrent fallers and non-fallers with Parkinson's disease during single- and dual-task walkingon 26 août 2026
Parkinsonism Relat Disord. 2026 Aug 16;151:108941. doi: 10.1016/j.parkreldis.2026.108941. Online ahead of print.ABSTRACTBACKGROUND: Falls are common in people with Parkinson's disease (PD) and are […]
- Population Attributable Risk in Alzheimer and Parkinson Diseaseson 26 août 2026
Neurol Genet. 2026 Jul 16;12(4):e200415. doi: 10.1212/NXG.0000000000200415. eCollection 2026 Aug.ABSTRACTOBJECTIVES: Emerging evidence suggests that the genetic architecture of Alzheimer disease (AD) […]
- Where does excessive beta in Parkinson's disease originate? Insights from a case of unilateral cortico-pallidal pathway dysfunctionon 26 août 2026
J Parkinsons Dis. 2026 Jul 30:1877718X261471025. doi: 10.1177/1877718X261471025. Online ahead of print.ABSTRACTPlain language summaryDetecting the source of abnormal beta oscillations in Parkinson's […]
- Beyond motor fluctuations: Understanding the clinical correlates of OFF burden in Parkinson's diseaseon 26 août 2026
J Parkinsons Dis. 2026 Aug 2:1877718X261442857. doi: 10.1177/1877718X261442857. Online ahead of print.ABSTRACTBackgroundHistorically, OFF burden in Parkinson's disease has been primarily attributed […]
- Juvenile Parkinson's disease: Symptom burden and treatment challengeson 26 août 2026
J Parkinsons Dis. 2026 Aug 5:1877718X261473047. doi: 10.1177/1877718X261473047. Online ahead of print.ABSTRACTJuvenile Parkinson's disease (JPD) is a rare condition characterized by the onset of […]
- Prevalence, predictors, and emerging biomarkers for cognitive impairment and neuropsychiatric manifestations in Parkinson's disease in Africa: A systematic reviewon 26 août 2026
J Parkinsons Dis. 2026 Aug 14:1877718X261479269. doi: 10.1177/1877718X261479269. Online ahead of print.ABSTRACTBackgroundCognitive impairment and neuropsychiatric manifestations are common disabling […]
Traitements pharmacologiques
Médicaments
- Comparative neuroprotective effects of antidiabetic medications on Parkinson's disease risk: a Bayesian network meta-analysison 26 août 2026
J Glob Health. 2026 Aug 21;16:04187. doi: 10.7189/jogh.16.04187.ABSTRACTBACKGROUND: Diabetes mellitus is recognised as a risk factor for Parkinson's disease (PD); however, comparative evidence […]
- Helicobacter pylori eradication status is associated with lower motor severity despite similar levodopa pharmacokinetics in Parkinson's diseaseon 26 août 2026
Parkinsonism Relat Disord. 2026 Aug 25;151:108949. doi: 10.1016/j.parkreldis.2026.108949. Online ahead of print.ABSTRACTBACKGROUND: Helicobacter pylori (H. pylori) infection has been associated with […]
- Pharmacokinetic-guided Management of Foslevodopa/Foscarbidopa infusion in PINK1-related Parkinson's disease with neuropsychiatric vulnerabilityon 26 août 2026
Clin Park Relat Disord. 2026 Jul 25;15:100487. doi: 10.1016/j.prdoa.2026.100487. eCollection 2026.NO ABSTRACTPMID:42564966 | PMC:PMC13446294 | DOI:10.1016/j.prdoa.2026.100487
- Muscular torque variability in Parkinson's Disease with and without dopaminergic medicationon 26 août 2026
Neurophysiol Clin. 2026 Jul 29;56(5):103190. doi: 10.1016/j.neucli.2026.103190. Online ahead of print.ABSTRACTWe examined whether dopaminergic medication improves sustained muscular torque/force […]
- Symptom prevalence and pharmacological management of late-stage Parkinson's disease (LSPD): a cross-sectional, multinational surveyon 26 août 2026
J Neural Transm (Vienna). 2026 Aug 21. doi: 10.1007/s00702-026-03255-4. Online ahead of print.ABSTRACTLate-stage Parkinson's disease (LSPD) presents with disabling motor and non-motor symptoms, the […]
- Comparative outcomes and healthcare costs of three device-aided pharmacotherapies for patients with advanced Parkinson's disease in Sweden: A nationwide registry-based cohort studyon 26 août 2026
Parkinsonism Relat Disord. 2026 Aug 19;151:108946. doi: 10.1016/j.parkreldis.2026.108946. Online ahead of print.ABSTRACTBACKGROUND: Patients with advanced Parkinson's disease often require treatment […]
- Dopamine depletion in Parkinson's increases directed but not random explorationon 26 août 2026
Sci Adv. 2026 Aug 7;12(32):eaee6556. doi: 10.1126/sciadv.aee6556. Epub 2026 Aug 5.ABSTRACTWe investigated how patients with Parkinson's disease (PD) manage the explore-exploit trade-off in a […]
- Effect of continuous subcutaneous foslevodopa/foscarbidopa infusion on gait in advanced Parkinson's disease: a real-world wearable-based studyon 26 août 2026
J Neurol. 2026 Jul 22;273(8):481. doi: 10.1007/s00415-026-14022-6.ABSTRACTBACKGROUND: In patients with advanced Parkinson's disease (PD), spatiotemporal gait parameters and freezing of gait (FoG) […]
Études cliniques phase 3 et phase 4
- New guidance and public search portal for clinical trials approved in Canada: Noticeon 26 août 2026
Our file number: 26-104462-113 July 29, 2026 On this page What we did About the guidance document About the search portal Contact us What we did Health Canada has a new guidance on […]
- Exendin-4 improves neurodevelopmental outcome after neonatal germinal matrix hemorrhageon 26 août 2026
Cell Death Dis. 2026 Aug 19;17(1):743. doi: 10.1038/s41419-026-09189-9.ABSTRACTGerminal matrix hemorrhage (GMH) is a common complication in premature infants and is associated with a high risk of […]
- Semaglutide as a potential neuroprotective agent for neurological and neurodegenerative disorders: Mechanisms, preclinical evidence, and translational challenges and opportunitieson 26 août 2026
Mol Biol Rep. 2026 Aug 10;53(1):1373. doi: 10.1007/s11033-026-12549-5.ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1 RAs) are established treatments for metabolic disease, with growing […]
- Optimizing participant recruitment and retention in clinical studies by hearing the voice of persons with Parkinson'son 26 août 2026
J Parkinsons Dis. 2026 Aug 14:1877718X261479268. doi: 10.1177/1877718X261479268. Online ahead of print.ABSTRACTBackgroundRecruitment and retention remain major barriers to clinical research in […]
Traitements non pharmacologiques
Chirurgie
- Burst deep brain stimulation for Parkinson's disease: A systematic review of efficacy and safetyon 26 août 2026
J Parkinsons Dis. 2026 Aug 1:1877718X261474705. doi: 10.1177/1877718X261474705. Online ahead of print.ABSTRACTBackgroundBurst deep brain stimulation (DBS) is a promising alternative to conventional […]
- Reduced Left vmPFC-STN-Related White Matter Integrity Is Associated with Pre-Surgical Apathy in Parkinson's Diseaseon 26 août 2026
Brain Stimul. 2026 Aug 14:103183. doi: 10.1016/j.brs.2026.103183. Online ahead of print.ABSTRACTINTRODUCTION: Apathy is a common and disabling non-motor symptom in Parkinson's disease (PD) that can […]
- Effects of subthalamic nucleus deep brain stimulation on sleep quality and daytime sleepiness in Parkinson's disease: a systematic review and meta-analysison 26 août 2026
Neurol Res. 2026 Aug 18:1-19. doi: 10.1080/01616412.2026.2717709. Online ahead of print.ABSTRACTBACKGROUND: Subthalamic nucleus deep brain stimulation (STN-DBS) is an established treatment for motor […]
- Deep-brain Neuromodulation in Parkinson's Disease: Convergent Mechanisms and Translational Stratification of Deep Brain Stimulation and Low-intensity Focused Ultrasoundon 26 août 2026
Ultrasound Med Biol. 2026 Aug 17:S0301-5629(26)00304-2. doi: 10.1016/j.ultrasmedbio.2026.07.030. Online ahead of print.ABSTRACTParkinson's disease (PD) involves not only dopaminergic degeneration but […]
- Full recovery after severe bacterial encephalitis and brain abscess following deep brain stimulation surgery for Parkinson's diseaseon 26 août 2026
J Parkinsons Dis. 2026 Jul 30:1877718X261470302. doi: 10.1177/1877718X261470302. Online ahead of print.ABSTRACTEncephalitis and cerebral abscesses are rare, serious complications of deep brain […]
Approches multidisciplinaires
- Retinal neurovascular signatures in response to 6-month yoga exercise in patients with Parkinson's Diseaseon 26 août 2026
Parkinsonism Relat Disord. 2026 Jul 27;150:108906. doi: 10.1016/j.parkreldis.2026.108906. Online ahead of print.ABSTRACTPURPOSE: To characterize retinal neurovascular signatures in response to a […]
- Social interaction enhances the pleasurable urge to move to music in people with Parkinson's diseaseon 26 août 2026
J Parkinsons Dis. 2026 Jul 28:1877718X261469682. doi: 10.1177/1877718X261469682. Online ahead of print.ABSTRACTBackgroundMusic- and dance-based interventions can improve motor symptoms in people with […]
- Serious games and virtual reality in Parkinson's disease rehabilitation: A systematic review of randomized controlled trialson 20 juillet 2026
Parkinsonism Relat Disord. 2026 Jun 30;149:108408. doi: 10.1016/j.parkreldis.2026.108408. Online ahead of print.ABSTRACTBACKGROUND: Serious games (SG) and virtual reality (VR) are emerging […]
Thérapies alternatives
- Walking with blood flow restriction in Parkinson's disease: vascular, neurotrophic and functional outcomes: a randomized controlled trial (WALK-BFR-PD Trial)on 26 août 2026
Eur J Appl Physiol. 2026 Aug 13. doi: 10.1007/s00421-026-06395-3. Online ahead of print.ABSTRACTBACKGROUND: Blood flow restriction (BFR) training induces beneficial adaptations at low exercise […]
- Cognitive-behavioral therapy in people with Parkinson's disease and caregivers: A mixed method systematic review on clinical applications and therapeutic outcomeson 26 août 2026
J Parkinsons Dis. 2026 Aug 11:1877718X261457793. doi: 10.1177/1877718X261457793. Online ahead of print.ABSTRACTBackgroundCognitive behavioral therapy (CBT) has emerged as a promising intervention in […]
- The effect of probiotic supplementation on constipation in patients with Parkinson's disease: A randomized controlled trialon 26 août 2026
Curr J Neurol. 2025 Jul 6;24(3):195-203. doi: 10.18502/cjn.v24i3.21596.ABSTRACTBackground: Constipation is a common non-motor symptom (NMS) in Parkinson's disease (PD), affecting up to 70% of […]
- Blue light therapy delivered through light glasses improves sleep quality and daytime sleepiness in Parkinson's disease: A randomized trialon 26 août 2026
J Parkinsons Dis. 2026 Aug 6:1877718X261468544. doi: 10.1177/1877718X261468544. Online ahead of print.ABSTRACTBackgroundSleep disturbances, including excessive daytime sleepiness (EDS) and fragmented […]
- Meditation and breathwork on anxiety in Parkinson's disease: A pilot randomized controlled trialon 26 août 2026
J Parkinsons Dis. 2026 Aug 6:1877718X261463924. doi: 10.1177/1877718X261463924. Online ahead of print.ABSTRACTBackgroundAnxiety and other non-motor symptoms can greatly diminish quality of life in […]
- Beyond Conventional Therapy in Parkinson's Disease Patients: The Impact of Visual Feedback Training on Balance and Trunk Control - A Prospective Cohort Studyon 26 août 2026
NeuroRehabilitation. 2026 Aug 21:10538135261473286. doi: 10.1177/10538135261473286. Online ahead of print.ABSTRACTBackgroundPostural instability and impaired balance are major contributors to […]
- Exercise, exerkines, and muscle-brain crosstalk in Parkinson's diseaseon 29 juillet 2026
Neuroprotection. 2026 Feb 25;4(2):99-110. doi: 10.1002/nep3.70032. eCollection 2026 Jun.ABSTRACTParkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non-motor symptoms, […]
Qualité de vie des patients
- Exploring changes in couples' functioning throughout Parkinson's diseaseon 26 août 2026
Br J Health Psychol. 2026 Sep;31(3):e70101. doi: 10.1111/bjhp.70101.ABSTRACTOBJECTIVES: Couples facing Parkinson's disease (PD) deal with continuous adaptation to the numerous challenges PD brings, […]
- Subjective Outcomes of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: Insights from Patients and Caregiverson 26 août 2026
Ann Indian Acad Neurol. 2026 Aug 4. doi: 10.4103/aian.aian_1013_25. Online ahead of print.ABSTRACTSubthalamic nucleus deep brain stimulation (STN-DBS) is an effective intervention for managing […]
- Longitudinal Associations between Depression, Daytime Sleepiness, and Caregiver Strain in Parkinson's Diseaseon 26 août 2026
Mov Disord Clin Pract. 2026 Aug 4. doi: 10.1002/mdc3.70759. Online ahead of print.ABSTRACTOBJECTIVE: Examine the longitudinal relationship between caregiver strain and Parkinson's patient depression, […]
- Reducing caregiver burden in Parkinson's disease: real-world insights from the Pezzoli Foundation's Family Centeron 26 août 2026
Parkinsonism Relat Disord. 2026 Jul 27;150:108907. doi: 10.1016/j.parkreldis.2026.108907. Online ahead of print.NO ABSTRACTPMID:42531987 | DOI:10.1016/j.parkreldis.2026.108907
- Location of Neurostimulation Affects Short-Term Emotional Wellbeing Outcomes in Parkinson's Disease Patientson 26 août 2026
Stereotact Funct Neurosurg. 2026 Jul 29:1-17. doi: 10.1159/000553012. Online ahead of print.ABSTRACTINTRODUCTION: Emotional wellbeing is a major determinant of quality of life (QoL) in Parkinson's […]
Technologies de soutien
- Better Conversations With Parkinson's: Feasibility and Acceptability of a Novel Communication Partner Training Telehealth Interventionon 26 août 2026
Int J Lang Commun Disord. 2026 Sep-Oct;61(5):e70308. doi: 10.1111/1460-6984.70308.ABSTRACTBACKGROUND: Communication Partner Training (CPT) has an established evidence base in aphasia, dementia and […]
- The Improvement Effects of Virtual Reality-Assisted Exercise Training on Motor and Psychiatric Symptoms in Patients With Parkinson's Disease: A Meta-Analysis of Randomized Controlled Trialson 26 août 2026
Actas Esp Psiquiatr. 2026 Aug 15;54(4):1269-1286. doi: 10.62641/aep.v54i4.2301.ABSTRACTBACKGROUND: This study aimed to systematically evaluate the combined improvement effects of virtual reality […]
- Quality Evaluation Using the Mobile App Rating Scale for Speech Therapy in Parkinson Disease: Systematic Search and Evaluationon 26 août 2026
JMIR Form Res. 2026 Aug 24;10:e72214. doi: 10.2196/72214.ABSTRACTBACKGROUND: As the global population ages, Parkinson disease (PD) has emerged as the second most prevalent neurodegenerative condition […]
- Using Wearable Devices to Monitor Activity and Sleep in Inpatients With Parkinson Disease With and Without Delirium: Feasibility and Acceptability Studyon 26 août 2026
J Med Internet Res. 2026 Jul 23;28:e91009. doi: 10.2196/91009.ABSTRACTBACKGROUND: Delirium is a serious condition characterized by an acute change in attention, arousal, and sleep disturbance. It is […]
Associations et ordres professionnels
Québec
- 📣 Recherche de participantson 26 août 2026
📣 Recherche de participants L’Université McGill recrute des personnes vivant avec la maladie de Parkinson, âgées de 40 à 80 ans, pour une étude sur les effets de l’exercice physique sur […]
- Photos from Parkinson Québec's poston 26 août 2026
Une édition HISTORIQUE grâce à vous ! ✨ Samedi dernier, 420 cyclistes ont pris le départ du Défi vélo Parkinson Québec avec une même volonté : soutenir les personnes touchées par la […]
- 🎉 C'est officiel : le Défi Vélo Parkinson Québec affiche COMPLET !on 26 août 2026
🎉 C'est officiel : le Défi Vélo Parkinson Québec affiche COMPLET ! À une semaine de l'événement, toutes les places ont trouvé preneur. Une première dans l'histoire du Défi Vélo et un […]
- 🎉🚴♀️ 200 000 $ amassés pour le Défi Vélo Parkinson Québec 2026!on 26 août 2026
🎉🚴♀️ 200 000 $ amassés pour le Défi Vélo Parkinson Québec 2026! Grâce à l'engagement de nos participants, de nos équipes corporatives, de nos partenaires et de nos donateurs, […]
- 📣 Découvrez Arts4PD – Une nouvelle ressource pour la communauté Parkinson !on 26 août 2026
📣 Découvrez Arts4PD – Une nouvelle ressource pour la communauté Parkinson ! ENGLISH FOLLOWS Parkinson Québec est fier d’être partenaire communautaire d’Arts4PD, une nouvelle […]
Canada
- Un simple test sanguin pourrait-il accélérer le diagnostic de la maladie de Parkinson ?on 26 août 2026
Principaux points à retenir Le diagnostic du Parkinson repose actuellement uniquement sur l’observation clinique – il n’existe toujours pas de test sanguin, et aucun test à lui seul ne […]
- Explorer de nouvelles façons de cibler les symptômes du Parkinson sans chirurgieon 26 août 2026
Je m’appelle Dr Martin McKeown. Je suis professeur, chef de la Division of Neurologie, et je suis directeur de John Nichol pour la recherche sur le Parkinson à l’Université de la […]
États-Unis
- How lost coordination might better explain Parkinson’s diseaseon 26 août 2026
One of the strangest things about living with Parkinson’s disease is how inconsistent it can be. A movement that feels nearly impossible one moment can sometimes become easier a few seconds later. […]
- Study shows a subtle shift in gut bugs with Parkinson’s gene mutationon 26 août 2026
People with Parkinson’s disease who carry mutations in the GBA1 gene tend to have higher levels of inflammation-promoting gut bacteria and fewer protective microbes than patients without the […]
- Electrified acupuncture shown to help ease gut issues in Parkinson’s miceon 26 août 2026
Digestive problems in Parkinson’s disease may be explained by the reduced activity of a specific type of nerve cells, called cholinergic neurons, in a particular brain region that helps regulate […]
- Brain imaging data don’t improve Parkinson’s prediction modelson 26 août 2026
Brain imaging data are not very useful for computer models predicting the long-term trajectory of Parkinson’s disease, a study showed. Researchers found that computer models aimed at predicting […]
- Early rehabilitation linked to longer survival in Parkinson’s, study suggestson 26 août 2026
Starting rehabilitation within the first year after a Parkinson’s disease diagnosis may be associated with longer survival, even among people who had already developed disability, a nationwide […]
- FDA fast-tracks experimental vaccine aiming to slow early Parkinson’son 26 août 2026
The U.S. Food and Drug Administration (FDA) has awarded fast-track designation — a status that aims to speed the development of promising treatments for serious conditions — to a Swiss […]
- Tai Chi may ease Parkinson’s motor symptoms, improve physical functionon 26 août 2026
Practicing Tai Chi four times a week may lessen motor symptoms and improve physical function and quality of life in people with early- to mid-stage Parkinson’s disease, a small clinical trial […]
- New drug eases Parkinson’s symptoms, cuts inflammationon 26 août 2026
People with early Parkinson’s disease who received the oral therapy bezisterim in a Phase 2 clinical trial saw significant improvements in a measure of symptom severity compared with patients given […]
- Webinar: Disease Modification & Stem Cells: Where Are We Now?on 26 août 2026
3 new Expert Briefing webinars taking place this fall… […]
- California moves to phase out paraquaton 26 août 2026
Momentum Builds to End Paraquat Use and Protect the Parkinson’s Community On August 10, the California Department of Pesticide Regulation announced that all manufacturers of pesticide […]
International
- Expert advice on how to help manage constipation in Parkinson’son 26 août 2026
With around 65% of people with Parkinson’s affected by constipation, it’s a common symptom which can be annoying and uncomfortable to manage. While it’s easy to become obsessed with bowel […]
- Improving diversity in science will move Parkinson’s research forwards, says UK researcheron 26 août 2026
Dr Dayne Beccano-Kelly has been active in Parkinson’s research for around 15 years, and for the past five years has been Group Leader at Cardiff University’s UK Dementia Research Institute, a […]
- 20 brilliant social media accounts about Parkinson’s to follow including Rory Cellan-Jones, Parkinsonsgirly and Michael J. Fox Foundationon 26 août 2026
Following social media accounts by, for and about the Parkinson’s community can be a great, low-demand way to connect and learn at your own pace. The online Parkinson’s community includes […]
- F*** Parkinson’s: how Apple TV’s ‘Shrinking’ created a social media mantra for the Parkinson’s communityon 26 août 2026
Michael J. Fox’s cameo appearance in the latest series of Apple TV drama Shrinking, which stars Harrison Ford as Paul, a therapist who has Parkinson’s, has inspired a new rallying cry that people […]
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