Description
Pratique en médecine transfusionnelle
- Short‐term temperature excursion does not affect plasma and cryoprecipitate qualityby Kelly M. Winter, Rachel G. Webb, Eugenia Mazur, Peta M. Dennington, Denese C. Marks on 3 juin 2026 at 15h44
Abstract Background and Objectives Plasma and cryoprecipitate are stored below −25°C for optimal preservation of component quality. However, there may be situations in which components are exposed to higher temperatures and therefore discarded. This study aimed to determine the quality of plasma and cryoprecipitate following a short-term […]
- A novel reagent for the screening of Immunoglobulin A‐deficient blood donorsby Naoko Watanabe‐Okochi, Ayaka Sato, Akira Okuyama, Go Tomiyoshi, Yumi Suzuki, Yukiko Watanabe, Masako Anazawa, Takashige Shimoyamada, Daisuke Takahashi, Takayuki Onodera, Makoto Uchikawa, Shigeki Miyata on 3 juin 2026 at 15h41
Abstract Background and Objectives Immunoglobulin A (IgA) deficiency occurs in approximately 1 in 14,000 individuals in Japan. Approximately 32% harbour anti-IgA, most of which are naturally occurring and rarely cause anaphylaxis, although high-titre anti-IgA from alloimmunization can cause severe reactions. A stable supply of IgA-deficient […]
- Implementation of a patient blood management programme for platelet therapy among haemato‐oncology patients—A quasi‐experimental studyby Vaidehi Prasanth, Daljit Kaur, Gita Negi, Gaurav Dhingra, Ashish Jain, Xavier Belsiyal, Chanchi B. Khiamniungan on 20 avril 2026 at 14h56
Abstract Background The paucity of data pertaining to the implementation of the patient blood management (PBM) programme for platelet transfusion for improved patient outcomes with minimal risks motivated this study. The study aimed to implement an effective PBM programme for platelet transfusion therapy among haemato-oncology patients […]
- Lower efficacy of transfusion of red blood cells from donors with sickle cell traitby Monika Dzieciatkowska on 20 avril 2026 at 14h55
Hemasphere. 2026 Apr 14;10(4):e70360. doi: 10.1002/hem3.70360. eCollection 2026 Apr.ABSTRACTSickle cell trait (SCT), the heterozygous state for the hemoglobin S (HbS) mutation, affects roughly 1 in 13 African American individuals and is common among blood donors recruited for antigen-matched transfusions in sickle cell disease (SCD). While […]
- Bridging the clinical equivalence gap: a nationwide survey on healthcare professionals' perceptions of whole blood-derived versus apheresis platelets in Chinaby Tie Cheng Sun on 20 avril 2026 at 14h48
Hematol Transfus Cell Ther. 2026 Apr 17;48(3):106453. doi: 10.1016/j.htct.2026.106453. Online ahead of print.ABSTRACTINTRODUCTION: Despite evidence supporting the clinical equivalence of whole blood-derived platelets (WBDP) and apheresis platelets (AP), AP remains the dominant choice for platelet transfusions in many countries. This study aimed to […]
- Simulation-Based Training to Promote Whole Blood Administration Protocol Among Critical Care Transport of Trauma Patientsby Olivia C Newbern on 20 avril 2026 at 14h45
Air Med J. 2026 Mar-Apr;45(2):121-125. doi: 10.1016/j.amj.2025.10.013. Epub 2025 Nov 25.ABSTRACTOBJECTIVE: Trauma patients often present to emergency departments with coagulopathies. Recognizing the unique challenges of caring for trauma patients and the urgent need for protocol-driven resuscitation is essential.METHODS: This project used a […]
- The Role of Artificial Intelligence in Transfusion Medicineby Bryce Pasko on 20 avril 2026 at 14h44
Clin Lab Med. 2026 Mar;46(1):119-136. doi: 10.1016/j.cll.2025.10.007. Epub 2025 Dec 26.ABSTRACTArtificial intelligence (AI) is rapidly transforming the field of transfusion medicine by enhancing precision, efficiency, and safety across the transfusion continuum. This article provides a comprehensive overview of AI technologies and their […]
- Management of burn patients is linked to the development of anti-HLA antibodies in patients receiving cryopreserved skin allografts: A retrospective cohortby Vicente Mirabet on 20 avril 2026 at 14h44
Burns. 2026 May;52(4):107967. doi: 10.1016/j.burns.2026.107967. Epub 2026 Mar 11.ABSTRACTINTRODUCTION: Skin allografts are used to cover wounds in patients with severe burns. Owing to the allogeneic nature of the tissue, rejection often limits its effectiveness to a few weeks. The aim of this study was to analyse the factors influencing […]
Réactions transfusionnelles
- Transfusion-transmitted cytomegalovirus infection in the era of universal leukoreduction and pathogen inactivation: a contemporary reviewby Poobalan Kirupanantha Rajan on 3 juin 2026 at 15h45
Lab Med. 2026 Apr 3;57(3):lmag031. doi: 10.1093/labmed/lmag031.ABSTRACTINTRODUCTION: Transfusion-transmitted cytomegalovirus remains a clinically significant risk in immunocompromised individuals, neonates, and transplant recipients. Despite widespread universal leukoreduction and pathogen-reduction technologies, uncertainty persists regarding […]
- Transfusion reactions reported to the Québec haemovigilance system between 2005 and 2022: A comparison of paediatric and adult recipientsby Nancy Robitaille on 20 avril 2026 at 14h48
Br J Haematol. 2026 Mar;208(3):1074-1083. doi: 10.1111/bjh.70371. Epub 2026 Feb 18.ABSTRACTFew studies have compared the prevalence of transfusion reactions (TRs) in paediatric and adult recipients, and none have been conducted in Canada. We carried out a retrospective cross-sectional study of TRs reported in a Canadian haemovigilance system (i.e. […]
- Transfusion-induces donor-specific antibody boost leading to antibody-mediated rejection after heart transplantation: A case reportby B Panaget on 20 avril 2026 at 14h47
Transpl Immunol. 2026 Apr;95:102365. doi: 10.1016/j.trim.2026.102365. Epub 2026 Feb 23.ABSTRACTDespite significant advances in immunosuppression strategies, antibody-mediated rejection (AMR) remains a leading cause of graft dysfunction and loss after heart transplantation. Donor-specific anti-HLA antibodies (DSA), either preformed or de novo, are […]
- The burden and correlates of bloodborne pathogens in a Zambian Blood Donor Cohortby Mwila Mapipo on 20 avril 2026 at 14h47
PLoS One. 2026 Apr 6;21(4):e0346680. doi: 10.1371/journal.pone.0346680. eCollection 2026.ABSTRACTINTRODUCTION: Transfusion is a critical life-saving intervention, but the safety of the blood supply remains a major public health concern, particularly in sub-Saharan Africa, due to the risk of transfusion-transmitted infections (TTIs). This study […]
- Mitochondrial DNA as a Damage-Associated Molecular Pattern in Stored Blood: Mechanisms of Transfusion-Induced Sterile Inflammationby Liangli Chen on 20 avril 2026 at 14h46
New Microbiol. 2026 Apr;49(1):11-17.ABSTRACTTransfusion of stored red blood cells (RBCs) is a life-saving intervention in trauma, surgery, and critical care. However, storage-induced alterations, collectively termed "storage lesions," lead to the accumulation of bioactive mediators, including mitochondrial DNA (mtDNA), which functions as a potent […]
- Adverse Reactions to Blood Transfusion in Pediatric Cardiac Surgery: A Retrospective Cohort Study at a Single Centerby V Nithin Krishna on 20 avril 2026 at 14h46
Ann Card Anaesth. 2026 Apr 1;29(2):204-211. doi: 10.4103/aca.aca_208_25. Epub 2026 Apr 15.ABSTRACTOBJECTIVES: Blood transfusion is an integral part of pediatric cardiac surgery. Our study intends to analyze the incidence of transfusion reactions in pediatric cardiac surgery patients. Secondary objectives were to identify the common type of […]
Transformation du sang
- Optimization and Performance Evaluation of Melt-Blown Fiber Membranes for Leukocyte Separation from Whole Bloodby Firdevs Mert Sivri on 3 juin 2026 at 15h33
ACS Omega. 2026 May 13;11(20):29683-29690. doi: 10.1021/acsomega.5c13313. eCollection 2026 May 26.ABSTRACTLeukocytes need to be eliminated from blood components in order to lower the risk of adverse transfusion responses and guarantee patient safety during transfusion. Nowadays, nonwoven fabric filters are typically used to remove leukocytes from […]
- An in-house nucleic acid test for detection of Anaplasma phagocytophilum in whole blood donor samplesby Dilini Kumaran on 20 avril 2026 at 14h51
Transfusion. 2026 Apr 13. doi: 10.1111/trf.70194. Online ahead of print.ABSTRACTBACKGROUND: Anaplasma phagocytophilum is a tick-borne pathogen that causes anaplasmosis. Increased incidences of this disease in Canada and cases of transfusion-transmitted anaplasmosis in the United States have been reported. Currently, there are no Health Canada […]
Banque du sang
- Organizational monitoring of patient blood management implementation: Results of an Italian national surveyby Vanessa Agostini on 3 juin 2026 at 15h24
Vox Sang. 2026 May 15. doi: 10.1111/vox.70267. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Patient blood management (PBM) as a standard-of-care approach, sustained by substantial scientific literature, is now widely supported by national and international recommendations and guidelines. Scientific evidence shows that PBM is a […]
- Reducing blood product wastage: Insights from a retrospective study in a tertiary health facilityby Jawaher Alsughayyir on 20 avril 2026 at 15h00
PLoS One. 2026 Mar 25;21(3):e0344521. doi: 10.1371/journal.pone.0344521. eCollection 2026.ABSTRACTINTRODUCTION: Due to the absence of prior institutional assessments and limited local studies lacking key performance indicators, this study examines the operational efficiency of the blood bank at King Fahad Medical City (KFMC) in Riyadh, Saudi […]
- The efficacy of interactive communication interventions for motivating blood donation: A systematic reviewby Louisa Boult, Tom Douglass, Madeleine Tremblett, Jack B. Joyce on 20 avril 2026 at 14h59
Abstract Background and Objectives The global blood product shortage is a persistent problem that urgently needs addressing. Research has investigated the effects of incentives, different interventions and different modes of communication on promoting blood donation; yet, there has been no systematic review comparing interactive […]
- Low titer group O whole blood inventory conservation: The effect of implementing group A whole blood at a simulated civilian trauma centerby Emilie A. Jochumsen, Jennifer Gurney, Donald Jenkins, Jansen N. Seheult, Philip C. Spinella, Ulrik Sprogøe, Mark H. Yazer on 20 avril 2026 at 14h57
Abstract Background Substituting group A whole blood (GAWB) might relieve some of the burden on the low titer group O whole blood (LTOWB) inventory. This simulation examined the effect of implementing GAWB at a large trauma hospital. Study Design and Methods A civilian trauma center with LTOWB and GAWB par levels set to 22 and 10 units, […]
- Effect of long-term frozen storage on antibodies in blood samples: immunoglobulin, tetanus toxin antibody, and ABO antibodyby Masamichi Mikame on 20 avril 2026 at 14h50
Immunohematology. 2026 Apr 10;42(1):6-13. doi: 10.2478/immunohematology-2026-003. Print 2026 Mar 1.ABSTRACTThe Japanese Red Cross Blood Services archives donor blood samples from all donations for look-back surveys. These samples, approximately 5 million per year, are stored frozen at -30°C for 11 years and are subsequently discarded. Because […]
- Latent iron deficiency as a silent driver of donor attrition in high-frequency plateletpheresis donors: a longitudinal cohort studyby Liqin Jin on 20 avril 2026 at 14h49
Ann Hematol. 2026 Apr 16;105(5):248. doi: 10.1007/s00277-026-06992-4.ABSTRACTHigh-frequency plateletpheresis is crucial for meeting transfusion demands but poses a significant risk of cumulative iron depletion in donors. Current screening protocols relying solely on hemoglobin (Hb) fail to detect latent iron deficiency (LID), a condition where […]
Maladies du sang
- Mortality and Functional Outcomes of Liberal versus Restrictive Blood Transfusion in Elderly Patients after Hip Surgery: A Randomised Control Trialby Virendra Eknath Patil on 3 juin 2026 at 15h27
Hip Pelvis. 2026 Jun 1;38(2):187-195. doi: 10.5371/hp.2026.38.2.187.ABSTRACTPURPOSE: There is ongoing debate on the haemoglobin level at which red cell transfusion should be administered following surgery. This study aimed to evaluate the benefits of a restrictive blood transfusion strategy and assess potential adverse effects of anaemia in the […]
- Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysisby Karthik Chetlapalli on 3 juin 2026 at 15h26
Blood. 2026 Jun 2:blood.2025032290. doi: 10.1182/blood.2025032290. Online ahead of print.ABSTRACTNon-myeloablative-related haploidentical allogeneic stem cell transplantation (NMAC-HID allo-HSCT) emerged as an additional treatment for achieving durable remission in SCD, a prevalent blood disorder characterized by painful vaso-occlusive crises and […]
- Stealth red blood cells with broad-spectrum antigenic shielding for transfusion therapy in antibody-mediated hemolytic anemiaby Ying Zhang on 3 juin 2026 at 15h25
Biomaterials. 2026 May 28;335:124345. doi: 10.1016/j.biomaterials.2026.124345. Online ahead of print.ABSTRACTRed blood cell (RBC) transfusion is a cornerstone of life-sustaining therapy, yet it is profoundly challenged in autoimmune hemolytic anemia (AIHA). In this disorder, a diverse array of autoantibodies targets both the autologous and […]
- Glycemic control and blood product quality of Canadian blood donors with diabetesby Elyn M. Rowe, Marcus Shew, Noor Ali‐Mohamad, Celina Phan, Mindy Goldman, Jason P. Acker, Dana V. Devine, James D. Johnson on 20 avril 2026 at 14h57
Abstract Background Many blood centers now accept donors with diabetes, provided their condition is “well-controlled”. However, glycemic control is not routinely assessed at donation, and the impact of donor diabetes on blood product quality remains unclear. Study Design and Methods To screen glycemic control, glycated hemoglobin A1c […]
- Evaluating Hemoglobin Thresholds for Blood Transfusions in Oncology Patients Admitted to the Intensive Care Unitby Barath Prashanth Sivasubramanian on 20 avril 2026 at 14h53
J Hematol. 2026 Apr 6;15(2):80-89. doi: 10.14740/jh2178. eCollection 2026 Apr.ABSTRACTBACKGROUND: In the intensive care unit (ICU), up to 90% of patients develop anemia during their stay. However, evidence regarding transfusion practices in oncology patients requiring ICU-level care is limited. This study aimed to compare mortality, survival rate, […]
- Risk factors for preoperative anemia in orthognathic surgery patients undergoing autologous blood donation: A cross-sectional studyby Sayaka Furuhashi on 20 avril 2026 at 14h43
Medicine (Baltimore). 2026 Apr 10;105(15):e48140. doi: 10.1097/MD.0000000000048140.ABSTRACTIn Japan, preoperative autologous blood donation (ABD) is widely performed in orthognathic surgery to avoid allogeneic transfusion. Although previous studies have examined postoperative hemoglobin (Hb) fluctuations and the safety of autologous blood […]
Utilisation de produits sanguins
- Longitudinal Changes in Transfusion Practice in Myelodysplastic Syndromes: A Population Data-Linkage Studyby Allison Mo on 3 juin 2026 at 15h28
Eur J Haematol. 2026 May 31. doi: 10.1111/ejh.70233. Online ahead of print.ABSTRACTBACKGROUND: Real-world data on transfusion needs of patients with myelodysplastic syndromes (MDS), and the impacts of disease-modifying therapies (DMTs) are sparse. In 2011, 5-azacitidine became the first funded DMT for MDS and chronic myelomonocytic leukaemia […]
- Beta-Thalassemia in Spain: Results From the National Thalassemia Registry and Molecular Analysis of Patients With Transfusion-Dependent Thalassemiaby Ana Villegas on 3 juin 2026 at 15h28
J Clin Lab Anal. 2026 Jun 2:e70272. doi: 10.1002/jcla.70272. Online ahead of print.ABSTRACTBACKGROUND: Beta-thalassemia is a genetically heterogeneous hemoglobinopathy with marked clinical variability. In Spain, comprehensive nationwide data on transfusion-dependent beta-thalassemia (TDT) remain limited, particularly regarding molecular […]
- An in‐house nucleic acid test for detection of Anaplasma phagocytophilum in whole blood donor samplesby Dilini Kumaran, Carmen Charlton, Chantale Pambrun, Steven J. Drews, Sandra Ramirez‐Arcos on 20 avril 2026 at 14h58
Abstract Background Anaplasma phagocytophilum is a tick-borne pathogen that causes anaplasmosis. Increased incidences of this disease in Canada and cases of transfusion-transmitted anaplasmosis in the United States have been reported. Currently, there are no Health Canada licensed methodologies available for detection of A. phagocytophilum […]
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