Description
Innovations - Découvertes
Mais aussi des synthèses, des études, des réflexions et des recherches.
- Wearable Devices and Machine Learning in Cardiovascular Monitoring: Current Evidence and Future Directions for Precision Medicine
Author Names: Osonuga, A.,Dave, M.,Ogieuhi, I.J.,Olawade, D.B.,Boussios, S. Database Source: Embase Daily Updates Journal Title: Journal of […]
- Context-agnostic machine learning for Parkinson's disease motor symptom detection using wearable sensors
Author Names: Giannakopoulou, K.-M.,Tsakanikas, P.,Roussaki, I. Database Source: Embase Daily Updates Journal Title: BMC medical informatics […]
- Exploring Parents' Values in Healthcare Decision-Making for Rare Genetic Neurodevelopmental Disorders: A Qualitative Study to Inform Guideline Development
J Intellect Disabil Res. 2026 Aug 9. doi: 10.1111/jir.70150. Online ahead of print.ABSTRACTBACKGROUND: Healthcare decision-making for individuals with rare genetic neurodevelopmental disorders […]
- Clinical and genomic determinants of extraordinary response and resistance to androgen receptor pathway inhibitors in men with metastatic androgen pathway modulator sensitive (APMS) prostate cancer
Prostate Cancer Prostatic Dis. 2026 Aug 5. doi: 10.1038/s41391-026-01145-0. Online ahead of print.ABSTRACTBACKGROUND: Identifying clinical and genomic predictors of response to androgen deprivation […]
- Genomic and molecular landscape of early onset colorectal cancer: Emerging insights and clinical implications-A systematic review
Surgery. 2026 Jul 2;198:110430. doi: 10.1016/j.surg.2026.110430. Online ahead of print.ABSTRACTBACKGROUND: Early onset colorectal cancer, defined as colorectal malignancy occurring before age 50, has […]
- Proteomic Biomarker Discovery in Breast Cancer: Advances, Challenges, and Translational Prospects
J Biochem Mol Toxicol. 2026 Aug;40(8):e71049. doi: 10.1002/jbt.71049.ABSTRACTBreast cancer remains a leading cause of cancer-related morbidity and mortality among women worldwide. Despite major […]
- Current Perspectives on Thyroid Nodule Evaluation: Integrating Cytomorphology, Ultrasound Risk Stratification, and Molecular Testing
Author Names: Pusztaszeri, M.P.,Baloch, Z.W. Database Source: Embase Daily Updates Journal Title: Modern pathology : an official journal of […]
- Precision medicine in asthma: endotype stratification, biomarker-guided biologics, and emerging therapeutic strategies
Mol Biol Rep. 2026 Jul 17;53(1):1185. doi: 10.1007/s11033-026-12357-x.ABSTRACTAsthma is a disease that has a high morbidity and health care burden impacting more than 300 million people worldwide, […]
- A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder
Dialogues Clin Neurosci. 2026 Dec;28(1):259-276. doi: 10.1080/19585969.2026.2700984. Epub 2026 Jul 19.ABSTRACTAttention-deficit/hyperactivity disorder (ADHD) affects 2.5% of adults and is associated […]
- Genomic innovations in cancer prevention, diagnosis, prognosis and precision therapeutics
Front Genet. 2026 Jul 6;17:1828450. doi: 10.3389/fgene.2026.1828450. eCollection 2026.ABSTRACTCancer research has undergone a transformative change with the advent of high-throughput genomic […]
- Exploring the use of machine and deep learning in genome-wide association studies: a comprehensive review
BioData Min. 2026 Jul 20. doi: 10.1186/s13040-026-00584-8. Online ahead of print.ABSTRACTThe advent of high-throughput sequencing technologies has generated increasingly large and complex genomic […]
- Capturing Perceived Utility from Qualitative Studies of Genomic Sequencing: Translating a Conceptual Model into a Working Codebook
AJOB Empir Bioeth. 2026 Jul 22:1-12. doi: 10.1080/23294515.2026.2691711. Online ahead of print.ABSTRACTINTRODUCTION: As genomic sequencing (GS) is integrated into clinical medicine, understanding how […]
Axes CHUM
Cet onglet concerne exclusivement les quatre axes qui suivent : oncologie, neurosciences, cardiovasculaire, imagerie et pré-greffe rénale.
- Reverse Imaging: Any-Sequence Generalization for Cardiac MRI Segmentation
IEEE Trans Med Imaging. 2026 Aug 5;PP. doi: 10.1109/TMI.2026.3720503. Online ahead of print.ABSTRACTPretrained segmentation models for cardiac magnetic resonance imaging (MRI) often fail to […]
- Photon-Counting CT for Interventional Oncology: Improving Vascular Mapping, Tumor Detection, and Personalized Treatment Strategies
Author Names: Chang, P.,Chiou, W. Database Source: Embase Daily Updates Journal Title: Insights into Imaging Article […]
- Application of metagenomic next-generation sequencing as an adjunct to conventional microbiological testing for the diagnosis of infection in kidney transplant recipients
Front Cell Infect Microbiol. 2026 Jul 17;16:1713707. doi: 10.3389/fcimb.2026.1713707. eCollection 2026.ABSTRACTBACKGROUND: Kidney transplant recipients are highly susceptible to opportunistic and […]
- Steroid Minimization in Kidney Transplantation: Rationale, Implementation, and Future Directions
Author Names: Cheungpasitporn, W.,Axelrod, D.A.,Caliskan, Y.,Lentine, K.L. Database Source: Embase Daily Updates Journal Title: American […]
- The combined impact of HLA and non-HLA mismatch between donors and recipients on kidney transplant survival: a genomic analysis in a prospective cohort
EBioMedicine. 2026 Aug 5;131:106420. doi: 10.1016/j.ebiom.2026.106420. Online ahead of print.ABSTRACTBACKGROUND: Kidney transplantation outcomes are strongly influenced by immunological compatibility […]
- Multicentre, controlled, randomised and single-blind, adaptive phase IV protocol to evaluate effectiveness and cost-effectiveness of a pre-emptive genotyping strategy to optimise tacrolimus dosage in a pretransplant chronic kidney disease population cohort: iPHARMGx TRANSPGx nested clinical trial
BMJ Open. 2026 Aug 3;16(8):e109279. doi: 10.1136/bmjopen-2025-109279.ABSTRACTINTRODUCTION: Genetic variations impact drug response, driving the need for personalised medicine through pre-emptive […]
- Preemptive Pharmacogenetics in Renal Transplantation: A Real-World Assessment of Pharmacogenetic Actionability
Author Names: Chastagner, D.,Monchaud, C.,Arnion, H.,Picard, N.,Rerolle, J.-P.,Danthu, C.,Toure, F. Database Source: Embase Weekly Updates Journal […]
- Breast and Ovarian Cancer Among Individuals Undergoing BRCA1 and BRCA2 Testing
JAMA Netw Open. 2026 Jul 1;9(7):e2626334. doi: 10.1001/jamanetworkopen.2026.26334.ABSTRACTIMPORTANCE: Pathogenic variants in BRCA1 and BRCA2 confer substantial risks of breast and ovarian cancer; […]
- Gene-targeted versus broad-spectrum therapies in ALS: comparative lessons and strategic outlook
Author Names: Shen, Y.,Shen, S.,Luo, Z.-G. Database Source: Embase Weekly Updates Journal Title: Journal of Genetics and Genomics […]
- Un code génomique universel pour mieux surveiller les bactéries pathogènes - Institut Pasteur
Un code génomique universel pour mieux surveiller les bactéries pathogènes Institut Pasteur
- Metronomic Chemotherapy in Ovarian Cancer: Current Scenario and AI-Integrated Future Strategies
Author Names: Chauhan, R.,Das, S.K.,Singh, M.,Malhotra, L.,Goyal, R.,Mirza, S.,Nehra, K.,Merhi, M.,Al-Shabeeb Akil, A.S.,Bhat, A.A.,Uddin, S.,Tripathi, S. Database Source: […]
- Nanomedicine targeting neuroinflammatory pathways in Alzheimer's disease: a new frontier in inflammopharmacology
Inflammopharmacology. 2026 Jul 17. doi: 10.1007/s10787-026-02329-9. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a multifactorial neurodegenerative illness characterized by progressive […]
- Personalized dosimetry in molecular radiotherapy: Current advances and clinical challenges
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:96-98.ABSTRACTPersonalized dosimetry is increasingly recognized as a key component of molecular radiotherapy. The aim of this study is to present recent […]
- Theranostics of prostate cancer: PSMA and new targets
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:75-80.ABSTRACTThe aim of this presentation is to transfer the experience of the Institute of Nuclear Medicine at University College London Hospital with […]
- Systematic reanalysis of next-generation sequencing data in 101 neuromuscular disorder families enhances diagnostic yield, reveals intronic variants, and identifies a novel disease gene
J Neurol. 2026 Jul 20;273(8):475. doi: 10.1007/s00415-026-13994-9.ABSTRACTBACKGROUND: Neuromuscular disorders (NMDs) affect approximately 1 in 1,000 individuals and are clinically and genetically […]
- Gene/Genome Editing in Cardiovascular Biology and Disease
Curr Gene Ther. 2026 Jul 17. doi: 10.2174/0115665232453929260206091608. Online ahead of print.ABSTRACTINTRODUCTION: Cardiovascular diseases continue to be the leading cause of death worldwide. […]
- Exploring shared genetic pathways and gene interplay in major neurodegenerative diseases: a comprehensive review
Gene. 2026 Jul 20:150318. doi: 10.1016/j.gene.2026.150318. Online ahead of print.ABSTRACTNeurodegenerative diseases are progressive disorders that involve the loss and dysfunction of neurons. […]
- US real-world biomarker testing differences and treatment choice in advanced ovarian cancer: results of a retrospective study
Future Oncol. 2026 Jul;22(16):1997-2006. doi: 10.1080/14796694.2026.2691252. Epub 2026 Jul 16.ABSTRACTAIMS: Describe trends in real-world BRCA and homologous recombination deficiency (HRD) testing […]
Applicabilité
- Integrated Radioproteomic Modeling for Early Recurrence Prediction and Metabolic Characterization in Hepatocellular Carcinoma
JCO Precis Oncol. 2026 Jul;10(7):e2500745. doi: 10.1200/PO-25-00745. Epub 2026 Jul 29.ABSTRACTPURPOSE: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, with high […]
- Current Clinical Perspectives of Biomarkers in Respiratory Diseases: A Narrative Review
Author Names: Gurajala, S.,Pandurangam, G.,Fayyomi, A.K.A.,Abed, S.,Sardidi, N.S.,Alrayes, M.M.,Alsabhan, T.A.,Alajmi, S.H.,Alfaraj, A.,Al Ghannam, N.,Al Humoud, S.Y.,Al Yousif, G.F.,Alameri, […]
- Multifunctional Nano-Contrast Agent Carriers: From Traditional Platforms to Next-Generation Theranostic Applications in Molecular Imaging
Author Names: Mirzaee, D.,Ghasemzaei, M.,Ramezani Farani, M.,Huh, Y.S.,Gholami, A.,Seyedhamzeh, M.,Alipourfard, I.,Farsadrooh, M.,Saffari, M.,Mirzaei, M.,Akhavan, O.,Ghoreishian, S.M.,Riley, […]
- Structure-based redesign enables clinical translation of CAIX-targeted theranostics in clear cell renal cell carcinoma
Theranostics. 2026 Jul 20;16(14):8247-8262. doi: 10.7150/thno.134970. eCollection 2026.ABSTRACTCarbonic anhydrase IX (CAIX) is an interesting therapeutic target in clear cell renal cell carcinoma […]
- Clinical application of chest CT image screening combined with nanopore targeted sequencing in improving the diagnosis rate of pulmonary tuberculosis patients
Front Public Health. 2026 Jul 23;14:1826208. doi: 10.3389/fpubh.2026.1826208. eCollection 2026.ABSTRACTBACKGROUND: How to increase the diagnosis rate of pulmonary tuberculosis (PTB) has always been a […]
- Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2026 - Pharmacokinetic, pharmacogenetic and clinical aspects
Pharmacopsychiatry. 2026 Jul;59(4):166-295. doi: 10.1055/a-2860-7861. Epub 2026 Jul 2.ABSTRACTTDM involves measuring and interpreting drug concentrations in blood plasma or serum to optimize […]
- Translating genomic data into healthcare practice with the Singapore National Precision Medicine program
Perspective Published: 29 July 2026 Shih Wee Seow1 na1, Theresia Mina orcid.org/0000-0002-5360-99152 na1, Maxime Hebrard orcid.org/0000-0003-2346-45133,4, Nilanjana Sadhu […]
- Bridging Randomized Trial Efficacy and Real-World Effectiveness in Multiple Myeloma: Integrating Clinical Trials and Real-World Evidence for Individualized Care
Author Names: Martino, E.A.,Vigna, E.,Bruzzese, A.,Caserta, S.,Lucia, E.,Olivito, V.,Labanca, C.,Mendicino, F.,Alvaro, M.E.,Amodio, N.,D'Arrigo, G.,Tripepi, G.,Morabito, F.,Gentile, M. […]
- Application value of next generation sequencing technology for pathogen detection in patients with pulmonary infection and lung cancer
Am J Cancer Res. 2026 Jun 15;16(6):2367-2376. doi: 10.62347/UDZH4839. eCollection 2026.ABSTRACTThis study aimed to evaluate the clinical value of next-generation sequencing (NGS) in diagnosing […]
- Personalised approach to hypertension treatment: protocol for the HYPERMARKER randomised controlled trial
BMJ Open. 2026 Jul 16;16(7):e117869. doi: 10.1136/bmjopen-2026-117869.ABSTRACTINTRODUCTION: Blood pressure treatment response is variable in individual patients, and the choice of medical therapy is […]
- Genetic predisposition in gynecologic cancers: From knowledge to clinical management
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:81-83.ABSTRACTGenetic predisposition contributes significantly to the development of specific gynecologic cancers, particularly ovarian and endometrial […]
- Optimizing Treatment Strategies in the Bipolar Disorder Spectrum With Classical AI Approaches: Systematic Review of Performance, Bias, and Clinical Applicability
JMIR Ment Health. 2026 Jul 21;13:e93307. doi: 10.2196/93307.ABSTRACTBACKGROUND: Bipolar disorder (BD) is a complex and heterogeneous psychiatric condition, characterized by fluctuating clinical […]
- Opportunities and Challenges in Translating Genomics into Population Health Impact: Lessons from Familial Hypercholesterolemia
Public Health Genomics. 2026 Jul 21:1-13. doi: 10.1159/000553208. Online ahead of print.ABSTRACTFamilial hypercholesterolemia (FH) is a common, autosomal dominant genetic disorder characterized by […]
Publications CRCHUM
- Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
Cancer Treat Rev. 2026 Jul 16;149:103190. doi: 10.1016/j.ctrv.2026.103190. Online ahead of print.ABSTRACTPatient-derived xenografts (PDX) and patient-derived organoids (PDO) are widely used to model […]
- TRACR: an anterograde transneuronal tracing system for genetic access across synapses and longitudinal circuit analysis
bioRxiv [Preprint]. 2026 Jul 12:2026.02.08.704659. doi: 10.64898/2026.02.08.704659.ABSTRACTFollowing neural signals as they converge onto and diverge from individual neurons is central to […]
- Patient-Derived 3D Heart-On-a-Chip Model of Dilated Cardiomyopathy With Embedded Bead-Based Mapping of Tissue Contractility
Adv Healthc Mater. 2026 Jul 25:e71464. doi: 10.1002/adhm.71464. Online ahead of print.ABSTRACTDilated cardiomyopathy (DCM) is the leading cause of heart transplantation, with a 50% risk of […]
Enseignement - Didactique
- Using the Delphi Process in the Development of the Partnering to Build Understanding of Genomics Responsibly Community Health Worker (PREFER CHW) Research Education Program
J Public Health Manag Pract. 2026 Aug 7. doi: 10.1097/PHH.0000000000002432. Online ahead of print.ABSTRACTCONTEXT: Community Health Workers (CHWs) are increasingly involved in genomics-related […]
- Using SMART Goals to Support Genomic Integration in Nursing Education
J Nurs Educ. 2026 Jul 27:1-4. doi: 10.3928/01484834-20260612-02. Online ahead of print.ABSTRACTBACKGROUND: Persistent gaps in faculty capacity hinder the integration of genomics into nursing […]
- Nursing roles, competencies, and education in precision oncology: a scoping review
EClinicalMedicine. 2026 Jul 21;98:104080. doi: 10.1016/j.eclinm.2026.104080. eCollection 2026 Aug.ABSTRACTBACKGROUND: Nurses contribute across the precision cancer care pathway, providing continuous, […]
- Educational approaches to enhance genomics competencies among health sciences students: A scoping review with implications for nursing education
Nurse Educ Today. 2026 Jul 20;167:107299. doi: 10.1016/j.nedt.2026.107299. Online ahead of print.ABSTRACTINTRODUCTION: Genomics is increasingly recognized as essential for precision health, yet its […]
- The Lisbon Manifesto on Precision Cancer Education: A Call to Transform Cancer Education from Personalized Prevention to Personalized Care
J Cancer Educ. 2026 Jul 30. doi: 10.1007/s13187-026-02967-1. Online ahead of print.NO ABSTRACTPMID:42530852 | DOI:10.1007/s13187-026-02967-1
- Genetics in Dental Education: A Cross-Sectional Study of Instruction and Clinical Integration
J Dent Educ. 2026 Jul 30. doi: 10.1002/jdd.70338. Online ahead of print.ABSTRACTPURPOSE: Advances in genomic science and biomedical technology have positioned dentists as key contributors to […]
- An analysis of AI platforms: Can AI provide genetics education?
J Genet Couns. 2026 Aug;35(4):e70250. doi: 10.1002/jgc4.70250.ABSTRACTWith the introduction, free access, and proliferation of various artificial intelligence (AI) in unique platforms, patients have […]
- Developing an Educational Visual Tool to Support Families Considering Whole-Exome Sequencing in Japan
Pediatr Int. 2026 Jan-Dec;68(1):e70485. doi: 10.1111/ped.70485.ABSTRACTBACKGROUND: Whole-exome sequencing (WES) is increasingly used in pediatric diagnostics, yet families often struggle to […]
- Genomic science and the nurse educator's role: Promoting integration from curriculum to clinical practice
Author Names: Lim, A.G.,Laing, B.,Print, C. Database Source: Embase Daily Updates Journal Title: Nurse education today […]
- Metrics Used for the Evaluation of Chatbots Providing Cancer Genetic Risk Assessment and Education: Systematic Review
JMIR AI. 2026 Jul 15;5:e76400. doi: 10.2196/76400.ABSTRACTBACKGROUND: Chatbots have recently emerged as an alternative approach for delivering cancer risk assessment and genetic counseling. […]
- Integrating cases, enhancing interaction, and promoting learning through assessment: teaching reform and practical outcomes of medical genetics under the OBE concept
Yi Chuan. 2026 Jul;48(7):741-750. doi: 10.16288/j.yczz.25-302.ABSTRACTIn the new era, the teaching of Medical Genetics requires medical students to not only master solid knowledge, but also possess […]
- Precision Pedagogy in Anatomy Education: Integrating AI, Narrative Medicine, and Professional Stratification
Clin Anat. 2026 Jul 17. doi: 10.1002/ca.70192. Online ahead of print.ABSTRACTThe aim of this study was to investigate the effects of an AI-Narrative-Stratified (ANS) model and traditional anatomy […]
- Theranostics Education: Educators' Perspective
J Nucl Med Technol. 2026 Jul 21:jnmt.126.272782. doi: 10.2967/jnmt.126.272782. Online ahead of print.ABSTRACTThe rapid expansion of theranostics has increased the stress felt by many nuclear medicine […]
- Open science practices and feedback-based pedagogy in nanomedicine education: a moderated mediation model of glioma treatment competency
BMC Med Educ. 2026 Jul 21. doi: 10.1186/s12909-026-09948-4. Online ahead of print.ABSTRACTBACKGROUND: Nanomedicine education requires interdisciplinary integration that conventional didactic […]
- Gamification in genetics, genomics, and pharmacogenomics education: a bibliometric analysis of research trends, collaboration, and emerging themes (2000-2025)
Front Med (Lausanne). 2026 Jul 7;13:1824779. doi: 10.3389/fmed.2026.1824779. eCollection 2026.ABSTRACTThe rapid expansion of genomics and pharmacogenomics technologies has created an urgent need for […]
Actualité - Formation
- With Genome BC Support, BugSeq Advances Genomic Tools for Emerging Pathogens and Drug Resistance
The next infectious disease threat may not be one that public health laboratories already know how to find. Vancouver-based BugSeq is building genomic tools designed to help clinical and public […]
- Génome Québec obtient 30 millions, mais devra réduire ses programmes de recherche - La Presse
Génome Québec obtient 30 millions, mais devra réduire ses programmes de recherche La Presse
- Idées | Les dérives marchandes de la génomique - Le Devoir
Idées | Les dérives marchandes de la génomique Le Devoir
- Voir le cancer dans son ADN : aux origines de la médecine de précision - Gustave Roussy
Voir le cancer dans son ADN : aux origines de la médecine de précision Gustave Roussy
- International study identifies promising therapy to prevent relapses in rare neurological disease
ROCHESTER, Minn. — An international study led by Mayo Clinic researchers has identified interleukin-6 (IL-6) receptor blockers as a promising option for preventing relapses in myelin […]
- Quebec’s Genomic Medicine Policy will advance precision medicine - McGill University Health Centre
Quebec’s Genomic Medicine Policy will advance precision medicine McGill University Health Centre
- Mya Thompson is helping shape the future of Indigenous data governance in cancer research - Ontario Institute for Cancer Research
As part of a unique summer internship, Thompson is informing researcher training and data access procedures for the Ontario Hereditary Cancer Research Network (OHCRN). With a lifelong interest in […]
- Implementation of Cat-VRS in AnyVar and AnyVLM
The GA4GH Categorical Representation Specification (Cat-VRS) provides a formal data model and related tools to represent categorical variants. In this presentation, Jennifer Bowser (Nationwide […]
- La Coalition Priorité Cancer salue l'adoption de la Politique québécoise en médecine génomique : un levier concret pour transformer les soins - PR Newswire Canada
La Coalition Priorité Cancer salue l'adoption de la Politique québécoise en médecine génomique : un levier concret pour transformer les soins PR Newswire Canada
- Génome Canada nomme de nouveaux membres du conseil d’administration et la présidente du CCSI
Génome Canada a le plaisir d’annoncer la nomination de quatre nouveaux membres au conseil d’administration. Ces personnes apportent une expertise qui reflète la croissance continue et […]
- International Consortium on Newborn Sequencing (ICoNS) — ICoNS
Boston, MA • Oct 7- 8, 2026 Meet a few of this year’s presenters The Joseph B. Martin Conference Center at Harvard Medical School* was built […]
- Summary - Got Data? Evaluating Real-World Data Suitability to Inform Regulatory Decision-Making
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