Description
Innovations - Découvertes
Mais aussi des synthèses, des études et des recherches.
- A Computational Framework for Tailored Preventive Care Recommendations Using Electronic Health Records
Author Names: Luo X.,Zeleke J.,Puckett R.K.,Sears I.,Storey S. Database Source: Embase Daily Updates Journal Title: Studies in health […]
- Genetically programmable wearable devices for precision physiological and molecular monitoring
Author Names: He J.,Fu M.,An W.,Xu W.,Zhou J.,Chen Y.,Xia Z.,Jiang Z.,Yang G. Database Source: Embase Weekly Updates Journal Title: […]
- Addressing immortal time bias in precision medicine: Practical guidance and methods development
Author Names: Weymann D.,Krebs E.,Regier D.A. Database Source: Embase Daily Updates Journal Title: Health Services Research […]
- Distributional Cost-Effectiveness Analysis in Genomic Medicine: Considerations for Addressing Health Equity
Author Names: Smith H.S.,Buchanan J.,Goranitis I.,IJzerman M.J.,Lavelle T.A.,Marshall D.A.,Regier D.A.,Ungar W.J.,Weymann D.,Wordsworth S.,Phillips K.A.,Jansen J.P. Database […]
- 3D-Printing Service in Radiology: Emerging Technology and Point-of-Care Innovations for Efficient, Personalized Medical Care and Precise Treatment Planning
Author Names: Xuan P.Y. Database Source: Embase Daily Updates Journal Title: Journal of Medical Imaging and Radiation Sciences […]
- Exploring Gender Bias in AI for Personalized Medicine: Focus Group Study With Trans Community Members
Author Names: Buslon N.,Cirillo D.,Rios O.,del Rosario S.P. Database Source: Embase Daily Updates Journal Title: Journal of Medical Internet […]
- ENABLING A HEALTHIER FUTURE FOR ALL THROUGH PRECISION MEDICINE
Trans Am Clin Climatol Assoc. 2025;135:60-73.ABSTRACTThe National Institutes of Health's All of Us Research Program is building one of the most comprehensive research cohorts in the United States. […]
- Process evaluation of the implementation of a personalized digital care pathway tool using the RE-AIM framework
Author Names: Heijsters F.A.C.J.,Cornelissen E.C.,de Bruijne M.C.,Bouman M.,Mullender M.G.,van Nassau F. Database Source: Embase Daily Updates […]
- A comprehensive benchmark of tools for efficient genomic interval querying
Brief Bioinform. 2025 Jul 2;26(4):bbaf379. doi: 10.1093/bib/bbaf379.ABSTRACTEfficiently querying genomic intervals is fundamental to modern bioinformatics, enabling researchers to extract and analyze […]
- Synergistic innovation in organ-on-a-chip and organoid technologies: Reshaping the future of disease modeling, drug development and precision medicine
Author Names: Li B.,Tang Y.,Huang Z.,Ma L.,Song J.,Xue L. Database Source: Embase Daily Updates Journal Title: Protein & cell […]
Axes CHUM
Cet onglet concerne exclusivement les quatre axes qui suivent : oncologie, neurosciences, cardiovasculaire et imagerie.
- Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment
Author Names: Aljabali A.A.A.,Obeid M.A.,Bashatwah R.M.,Qnais E.,Gammoh O.,Alqudah A.,Mishra V.,Mishra Y.,Khan M.A.,Parvez S.,El-Tanani M.,Hatahet T. Database Source: […]
- Barriers and Breakthroughs in Precision Oncology: A National Registry Study of BRCA Testing and PARP Inhibitor Uptake in Women from the National Gynae-Oncology Registry (NGOR)
Author Names: Naidoo M.,Scott C.L.,Lloyd M.,McNally O.,Rome R.,Perera S.,Zalcberg J.R. Database Source: Embase Daily Updates Journal Title: […]
- Automating Precision Oncology Literature Curation: A Decision Tree Approach Using Large Language Models
Stud Health Technol Inform. 2025 Aug 7;329:248-252. doi: 10.3233/SHTI250839.ABSTRACTThe curation of precision oncology knowledge bases requires intensive screening of scientific literature. Large […]
- Starfish: Deciphering Complex Genomic Rearrangement Signatures Across Human Cancers
Methods Mol Biol. 2025;2932:105-123. doi: 10.1007/978-1-0716-4566-6_5.ABSTRACTComplex genomic rearrangements (CGRs) in cancer often originate from abnormal cellular structures such as micronuclei and […]
- Real-world findings from a multi-institutional quality study using CFIR to explore gaps, challenges, and opportunities around implementing precision medicine in community cancer settings
Author Names: Terrell C.,Keruakous A.R.,Schofield A.D.,Iska S.,Leurinda C.,Dalgetty M.,Waugh W.,Methuku N.K.,Martin J.,Donini R.,Richendollar K.,Reed E.L.,Qasem A.M.S.,Caughron S.K.,Marcello […]
- Optimizing Cardiovascular Risk Management in Primary Care Using a Personalized eCoach Solution Enhanced by an Artificial Intelligence-Driven Clinical Prediction Model: Protocol from the Coronary Artery Disease Risk Estimation and Early Detection Consortium
JMIR Res Protoc. 2025 Aug 8;14:e66068. doi: 10.2196/66068.ABSTRACTBACKGROUND: Atherosclerotic cardiovascular disease poses a heavy burden on the population's health and health care costs. Identifying […]
- Broadening the scope of multigene panel analysis for adult epilepsy patients
Author Names: Lee S.,Kang M.-K.,So K.H.,Jang R.,Shin Y.W.,Jang S.S.,Yoon J.G.,Kim S.,Kim M.,Chu K.,Lee S.K.,Kim K.J.,Baek S.T.,Lim B.C.,Moon J. Database Source: Embase […]
- NAVIGATOR: A regional multimodal imaging biobank initiative powered by AI tools for precision medicine in oncology
Author Names: Aghakhanyan G.,Barucci A.,Pascali M.A.,Assante M.,Bagnacci G.,Bertelli E.,Caputo F.P.,Cuibari M.E.,Carlini E.,Carpi R.,Caudai C.,Cioni D.,Colantonio S.,Colcelli V.,Dell'Amico […]
- TROP2-targeted molecular imaging: a promising tool for precision oncology
Author Names: Ye L.,Chen H.,Wu D. Database Source: Embase Daily Updates Journal Title: American Journal of Nuclear Medicine and Molecular […]
- Mapping the trajectory of psychotic symptoms and their interaction with antipsychotic treatment: a longitudinal network intervention study
Author Names: Sarti P.,Cecere G.,Edkins V.,Omlor W.,Blom J.M.C.,Homan P. Database Source: Embase Preprint Journal Title: medRxiv […]
- 3D Printing in Oral Drug Delivery: Technologies, Clinical Applications and Future Perspectives in Precision Medicine
Author Names: Saleh-Bey-Kinj Z.,Heller Y.,Socratous G.,Christodoulou P. Database Source: Embase Daily Updates Journal Title: Pharmaceuticals […]
- Tailoring antiseizure treatment with a wearable device: A proof-of-concept study in absence epilepsy
Author Names: Macea J.,Chatzichristos C.,Bhagubai M.,De Vos M.,Van Paesschen W. Database Source: Embase Weekly Updates Journal Title: […]
Applications cliniques
- Regulation of biomarker analysis: what can Be translated in the clinic?
Author Names: Diamantopoulos M.A.,Boti M.A.,Sarri T.,Tounias G.,Psychogyiou D.D.,Scorilas A. Database Source: Embase Daily Updates Journal Title: […]
- OnPOINT: Development of an open navigator through precision oncology informatics technology to support precision oncology decisions and genotype-matched clinical trial enrollment
Author Names: Botsis T.,Spiker J.,Kreimeyer K.,Jamali A.,Ziakas I.,Sherief M.,Fatteh M.,Wehr J.,Karaindrou K.,Najjar M.,Xian R.,Dobs A.,Imamovic N.,Pindzola A.,Tao J.,Van Liere Canzoniero […]
- Mayo Clinic treats first person in the US with a novel radiopharmaceutical therapy for breast cancer
Researchers are leading the nation in using powerful and precise radioactive drugs to treat people with complex cancers. ROCHESTER, Minn. — Mayo Clinic has treated the first person in the […]
- Targeting the MAP Kinase Pathway in Colorectal Cancer: A Journey in Personalized Medicine
Author Names: Appleyard J.W.,Williams C.J.M.,Manca P.,Pietrantonio F.,Seligmann J.F. Database Source: Embase Weekly Updates Journal Title: […]
- Individualised Medicine: Application of a Personalised Approach in Clinical Practice
Author Names: Maltsev D.,Tyravska Y.,Shpryakha Y.,Kaminskyy V.,Merzliak S. Database Source: Embase Daily Updates Journal Title: Journal of […]
- CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential
Author Names: Far B.F.,Akbari M.,Habibi M.A.,Katavand M.,Nasseri S. Database Source: Embase Daily Updates Journal Title: Cell Proliferation […]
- A clinical road map for single-cell omics
Author Names: Skinnider M.A.,Courtine G.,Bloch J.,Squair J.W. Database Source: Embase Daily Updates Journal Title: Cell […]
- Exploring Clinicians' and Patients' Acceptance and Utilization of a Digital Solution to Support Individualized Care in Diabetes Specialist Outpatient Care (DigiDiaS): Qualitative Study
JMIR Hum Factors. 2025 Jul 8;12:e70301. doi: 10.2196/70301.ABSTRACTBACKGROUND: With the increasing prevalence of type 1 diabetes alongside limited health care resources, the need for more sustainable […]
- Are we properly evaluating genetic and genomic testing? A systematic review of health technology assessment reports
J Transl Med. 2025 Jul 7;23(1):749. doi: 10.1186/s12967-025-06703-z.ABSTRACTBACKGROUND: Despite advances in precision medicine, the translation of genetic and genomic technologies into routine […]
- Radiomics for Precision Diagnosis of FAI: How Close Are We to Clinical Translation? A Multi-Center Validation of a Single-Center Trained Model
Author Names: Montin E.,Namireddy S.,Ponniah H.S.,Logishetty K.,Khodarahmi I.,Glyn-Jones S.,Lattanzi R. Database Source: Embase Daily Updates […]
Publications CRCHUM
- Exome Sequencing in Pacific Islanders With Nephropathies of Unknown Origin
Kidney Int Rep. 2025 Mar 10;10(6):2054-2057. doi: 10.1016/j.ekir.2025.03.005. eCollection 2025 Jun.NO ABSTRACTPMID:40630292 | PMC:PMC12230993 | DOI:10.1016/j.ekir.2025.03.005
- Moving Beyond Race, Geographical Origin, and Ethnicity: Genomic Insights as a Path Forward in Nephrology Care
Nephrol Dial Transplant. 2025 Jul 3:gfaf124. doi: 10.1093/ndt/gfaf124. Online ahead of print.NO ABSTRACTPMID:40608521 | DOI:10.1093/ndt/gfaf124
- The mutagenic forces shaping the genomes of lung cancer in never smokers
Nature. 2025 Jul 2. doi: 10.1038/s41586-025-09219-0. Online ahead of print.ABSTRACTLung cancer in never smokers (LCINS) accounts for around 25% of all lung cancers1,2 and has been associated with […]
- Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial
Nat Commun. 2025 Jul 1;16(1):5919. doi: 10.1038/s41467-025-60808-z.ABSTRACTIntegrated whole genome and transcriptome sequencing can unveil distinct molecular subgroups in pancreatic cancer (PDAC). […]
- TBpore cluster: A novel phylogenetic pipeline for tuberculosis transmission studies using nanopore next-generation sequencing data
PLoS One. 2025 Jun 16;20(6):e0325914. doi: 10.1371/journal.pone.0325914. eCollection 2025.ABSTRACTBACKGROUND: Molecular typing of Mycobacterium tuberculosis complex isolates enhances understanding of […]
- Nephrogenomics, precision medicine and the role of genetic testing in adult kidney disease management
Nat Rev Nephrol. 2025 Jun 16. doi: 10.1038/s41581-025-00970-1. Online ahead of print.ABSTRACTGenetic investigations in nephrology have long been viewed as the prerogative of paediatricians or […]
- A multi-ancestry genetic reference for the Quebec population
medRxiv [Preprint]. 2025 May 16:2025.05.14.25327536. doi: 10.1101/2025.05.14.25327536.ABSTRACTWhile international efforts have characterized genetic variation in millions of individuals, the […]
- High-resolution optical genome mapping unveils gene disruptions in a reciprocal chromosomal translocation and severe male infertility: a case report
J Assist Reprod Genet. 2025 Jun 4. doi: 10.1007/s10815-025-03521-6. Online ahead of print.ABSTRACTPURPOSE: This case report describes a 36-year-old male with primary infertility, associated with a […]
- Genetic diseases misdiagnosed as multiple sclerosis: Observational study and review of literature
Mult Scler Relat Disord. 2025 Apr 10;99:106439. doi: 10.1016/j.msard.2025.106439. Online ahead of print.ABSTRACTBACKGROUND: Adult-onset neurogenetic diseases (NGDs) with white matter abnormalities […]
- Mapping the peripheral immune landscape of Parkinson's disease patients with single-cell sequencing
Brain. 2025 May 26:awaf066. doi: 10.1093/brain/awaf066. Online ahead of print.ABSTRACTParkinson's disease is most recognized for its impact on the CNS. However, recent breakthroughs underscore the […]
Enseignement - Didactique
- Virtual Engagement in a Hybrid Community of Practice: A Descriptive Study on the Training and Integration of New Members into the Genomics Education Partnership during COVID-19
J STEM Educ. 2024 Apr-Jun;25(2):30-41. doi: 10.63504/jstem.v25i2.2651.ABSTRACTThis descriptive study examines the experiences of virtually-trained new members in a hybrid distributed community of […]
- Competency Framework Development for Genomics Nurse Educators: Defining a Specialty Role in Academic Nursing Education
Nurse Educ. 2025 Sep-Oct 01;50(5):253-259. doi: 10.1097/NNE.0000000000001947. Epub 2025 Aug 4.ABSTRACTBACKGROUND: As genomics becomes increasingly integral to health care, enhancing nurse educators' […]
- Genomics in pre-registration nurse education: A narrative review
Nurse Educ Pract. 2025 Aug 15;87:104504. doi: 10.1016/j.nepr.2025.104504. Online ahead of print.ABSTRACTAIM/OBJECTIVE: To identify and synthesise research on the development of nurse genomics […]
- AI-scending the scope: Perspectives on the integration and utilization of artificial intelligence and machine learning in genetic counseling graduate programs
J Genet Couns. 2025 Aug;34(4):e70065. doi: 10.1002/jgc4.70065.ABSTRACTIncreased utilization of artificial intelligence (AI) and machine learning (ML) in genomic medicine and genetic counseling […]
- Competency Framework Development for Genomics Nurse Educators: Defining a Specialty Role in Academic Nursing Education
Nurse Educ. 2025 Aug 4. doi: 10.1097/NNE.0000000000001947. Online ahead of print.ABSTRACTBACKGROUND: As genomics becomes increasingly integral to health care, enhancing nurse educators' competence in […]
- Educating the Next-Generation Expert in Nephrology Genetics
Semin Nephrol. 2025 Jul 15:151648. doi: 10.1016/j.semnephrol.2025.151648. Online ahead of print.ABSTRACTThe importance of genetics and genomics in general nephrology has rapidly ascended within the […]
- Does Education Design Matter? Evaluating an Evidence-Based Continuing Education Intervention on Genomic Testing for Primary Care; a Pre-Test Post-Test Study
J CME. 2025 Jul 21;14(1):2526234. doi: 10.1080/28338073.2025.2526234. eCollection 2025.ABSTRACTBACKGROUND: : Quality continuing education (CE) interventions should be effective, fit-for-purpose, and […]
- BioSTEM: A modern educational tool for research and innovation in the field of molecular biology and personalized medicine
Hum Genomics. 2025 Jul 14;19(1):82. doi: 10.1186/s40246-025-00786-x.ABSTRACTPersonalized Medicine has the potential to transform modern healthcare by tailoring medical decisions to an individual's […]
- Genomic literacy in nursing: a systematic scoping review of the literature
BMJ Open. 2025 Jul 13;15(7):e100054. doi: 10.1136/bmjopen-2025-100054.ABSTRACTOBJECTIVE: To map the available evidence on genomic literacy among clinical nurses, nursing students and nursing […]
- Genetic counseling training program perspectives on delivering disability-related education
J Genet Couns. 2025 Aug;34(4):e70070. doi: 10.1002/jgc4.70070.ABSTRACTEnsuring genetic counselors are educated about disability is crucial due to the societal implications of genetic testing and the […]
Actualité - Formation
- AI-generated genomes could accelerate precision medicine without compromising patient confidentiality - Ontario Institute for Cancer Research
OncoGAN generates simulated genomes that can be used to train genomic analysis tools without the confidentiality concerns associated with real genomes. A new AI system that creates simulated cancer […]
- Des chercheurs montréalais utilisent l’IA et des capteurs portables pour détecter l’inflammation avant l’apparition de symptômes
La médecine moderne est en grande partie réactive : elle intervient généralement une fois les symptômes apparus. Mais une nouvelle étude émanant de l’Institut de recherche du Centre […]
- Mayo Clinic AI tool finds early signs of blood mutations linked to cancer and heart disease
(Video animation shows blood stem cells dividing and multiplying. Getty Images). Deep inside the body, a slow-growing cluster of mutated blood cells can form. This cluster, found in 1 […]
- Rapport annuel de Génome Canada 2024-2025
Au nom du conseil d’administration et du personnel, nous sommes heureux de vous communiquer le Rapport annuel 2024-2025 de Génome Canada, Exploiter la génomique pour un meilleur impact.Depuis 25 […]
- Many All of Us participants give us samples of blood, urine, or saliva for research. These samples provide a lot of information about health and DNA. Researchers can study data from these samples to make discoveries. The samples are stored and protected in a lab called a biobank.
All of Us processes your samples and stores information about them on our secure computer systems. We lock samples in secure freezers and they are marked by ID numbers, not names or any other information that could identify the participant. Only a few authorized people can access them, and we make sure they are only used for health research: https://allof-us.org/4f3tJTW
#DNA #privacy #HealthResearch #JoinAllofUs
Many All of Us participants give us samples of blood, urine, or saliva for research. These samples provide a lot of information about health and DNA. Researchers can study data from these samples to […]
- GA4GH 13th Plenary
- Using AI to interpret prostate cancer MRIs could reduce radiologist workload and give more patients access - Ontario Institute for Cancer Research
A machine learning tool was able to accurately triage prostate cancer in OICR-supported research. New research suggests that AI has the potential to improve the efficiency of prostate cancer […]
- Communicating clearly about data sharing in genomics
Amorim M, Silva S, Maia T, de Freitas C. Benefits and risks of sharing genetic data for research purposes: the views of patients and carers. Eur J Pub Health, 30, Issue Supplement_5, September […]
- The perceived risks of sharing genomic data with researchers
About us Learn how GA4GH helps expand responsible genomic data use to benefit human health.Our Strategic Road Map defines strategies, standards, and policy frameworks to support responsible global […]
- Demande de propositions – Étude économique sur la génomique, la biotechnologie et la biorévolution
Génome Canada lance un appel d’offres et sollicite des propositions de la part d’entreprises ou de consortiums qualifiés afin de mener une étude de haute qualité sur l’impact économique de […]
- Mayo Clinic deploys NVIDIA Blackwell infrastructure to drive generative AI solutions in medicine
A group of consultants discuss and review a digital pathology image on a wall monitor. ROCHESTER, Minn. — Mayo Clinic took a pivotal step toward integrating AI solutions in the clinical […]
- Progress in gene therapy offers hope for long-term knee pain relief
Christopher Evans, Ph.D. For nearly three decades, Mayo Clinic researcher Christopher Evans, Ph.D., has pushed to expand gene therapy beyond its original scope of fixing rare, single-gene […]
- WHO establishes communities of practice for pathogen genomics surveillance
The International Pathogen Surveillance Network (IPSN), set up by the WHO Hub for Pandemic and Epidemic Intelligence, has set up three communities of practice (CoPs), each designed to drive […]
- Mayo Clinic researchers link CAR-T cell aging to cancer relapse
ROCHESTER, Minn. — Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the […]
- Pharmacogenomics expert advances precision medicine for bipolar disorder - EurekAlert!
Pharmacogenomics expert advances precision medicine for bipolar disorder EurekAlert!
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