Description
Innovations - Découvertes
Mais aussi des synthèses, des études, des réflexions et des recherches.
- Precision medicine in asthma: endotype stratification, biomarker-guided biologics, and emerging therapeutic strategies
Mol Biol Rep. 2026 Jul 17;53(1):1185. doi: 10.1007/s11033-026-12357-x.ABSTRACTAsthma is a disease that has a high morbidity and health care burden impacting more than 300 million people worldwide, […]
- A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder
Dialogues Clin Neurosci. 2026 Dec;28(1):259-276. doi: 10.1080/19585969.2026.2700984. Epub 2026 Jul 19.ABSTRACTAttention-deficit/hyperactivity disorder (ADHD) affects 2.5% of adults and is associated […]
- Genomic innovations in cancer prevention, diagnosis, prognosis and precision therapeutics
Front Genet. 2026 Jul 6;17:1828450. doi: 10.3389/fgene.2026.1828450. eCollection 2026.ABSTRACTCancer research has undergone a transformative change with the advent of high-throughput genomic […]
- Exploring the use of machine and deep learning in genome-wide association studies: a comprehensive review
BioData Min. 2026 Jul 20. doi: 10.1186/s13040-026-00584-8. Online ahead of print.ABSTRACTThe advent of high-throughput sequencing technologies has generated increasingly large and complex genomic […]
- Capturing Perceived Utility from Qualitative Studies of Genomic Sequencing: Translating a Conceptual Model into a Working Codebook
AJOB Empir Bioeth. 2026 Jul 22:1-12. doi: 10.1080/23294515.2026.2691711. Online ahead of print.ABSTRACTINTRODUCTION: As genomic sequencing (GS) is integrated into clinical medicine, understanding how […]
- Forced resilience: Indigenous perspectives on systemic barriers and humanizing genomic medicine in British Columbia, Canada
Author Names: Ehman, M.,Regier, D.A.,Montour, L.,Pollard, S.,Weymann, D.,Kirk, D.,Brown, K.,Epp, S.,Wadsworth, D.,Garrison, N.A.,Laberge, A.-M.,Caron, N.R.,Arbour, L. […]
- Readiness to Consider and Adopt Genetic and Genomic Tests in Canada-An Update to the State of Readiness Report
Curr Oncol. 2026 Jun 4;33(6):334. doi: 10.3390/curroncol33060334.ABSTRACT(1) Background: Genomic medicine-i.e., the use of laboratory-based biomarkers that measure the expression, function and […]
- Building CRISPR-Based Gene-Editing Platforms for Personalized Medicine: The Next Step in Interventional Genetics
Author Names: Rodriguez, S.H.,Yokota, T. Database Source: Embase Daily Updates Journal Title: Genes Article Title: […]
- Next-generation nanomedicine for MDR-TB: PROTAC nanocarriers, granuloma penetration, and AI-driven design
Author Names: Chaudhari, A.,Naik, J.,Kole, E.,Tade, R.,Chatterjee, A. Database Source: Embase Daily Updates Journal Title: Journal of Drug […]
- Exosomes as Disease-Informed Nanoplatforms for Pulmonary Fibrosis: From Pathogenic Signaling to Precision Diagnosis and Therapy
Author Names: Lee, J.M.,Kim, K.T.,Hwang, H.S.,Lee, C.-S. Database Source: Embase Daily Updates Journal Title: Pharmaceutics […]
- Tumor organoids as a revolutionary platform for advancing cancer nanomedicine
Author Names: Wu, C.,Chen, J.,Ji, J.,Tan, Y.,Liu, Z.,Wu, Q.,Zheng, X.,Zhang, C.,Luo, K.,Xiao, K. Database Source: Embase Weekly Updates Journal […]
- Precision Medicine in Inherited Retinal Disease: Advances, Challenges, and Future Directions
Author Names: Dhivagaran, T.,Butt, F.R.,Grover, K.,Devgan, K.,Sachdeva, K.,Dhivagaran, V.,Abid, F.,Tao, B.K.,Balas, M.,Dimopoulos, I.,Bhatti, A. Database Source: […]
Axes CHUM
Cet onglet concerne exclusivement les quatre axes qui suivent : oncologie, neurosciences, cardiovasculaire et imagerie.
- Gene-targeted versus broad-spectrum therapies in ALS: comparative lessons and strategic outlook
Author Names: Shen, Y.,Shen, S.,Luo, Z.-G. Database Source: Embase Weekly Updates Journal Title: Journal of Genetics and Genomics […]
- Un code génomique universel pour mieux surveiller les bactéries pathogènes - Institut Pasteur
Un code génomique universel pour mieux surveiller les bactéries pathogènes Institut Pasteur
- Metronomic Chemotherapy in Ovarian Cancer: Current Scenario and AI-Integrated Future Strategies
Author Names: Chauhan, R.,Das, S.K.,Singh, M.,Malhotra, L.,Goyal, R.,Mirza, S.,Nehra, K.,Merhi, M.,Al-Shabeeb Akil, A.S.,Bhat, A.A.,Uddin, S.,Tripathi, S. Database Source: […]
- Nanomedicine targeting neuroinflammatory pathways in Alzheimer's disease: a new frontier in inflammopharmacology
Inflammopharmacology. 2026 Jul 17. doi: 10.1007/s10787-026-02329-9. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a multifactorial neurodegenerative illness characterized by progressive […]
- Personalized dosimetry in molecular radiotherapy: Current advances and clinical challenges
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:96-98.ABSTRACTPersonalized dosimetry is increasingly recognized as a key component of molecular radiotherapy. The aim of this study is to present recent […]
- Theranostics of prostate cancer: PSMA and new targets
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:75-80.ABSTRACTThe aim of this presentation is to transfer the experience of the Institute of Nuclear Medicine at University College London Hospital with […]
- Systematic reanalysis of next-generation sequencing data in 101 neuromuscular disorder families enhances diagnostic yield, reveals intronic variants, and identifies a novel disease gene
J Neurol. 2026 Jul 20;273(8):475. doi: 10.1007/s00415-026-13994-9.ABSTRACTBACKGROUND: Neuromuscular disorders (NMDs) affect approximately 1 in 1,000 individuals and are clinically and genetically […]
- Gene/Genome Editing in Cardiovascular Biology and Disease
Curr Gene Ther. 2026 Jul 17. doi: 10.2174/0115665232453929260206091608. Online ahead of print.ABSTRACTINTRODUCTION: Cardiovascular diseases continue to be the leading cause of death worldwide. […]
- Exploring shared genetic pathways and gene interplay in major neurodegenerative diseases: a comprehensive review
Gene. 2026 Jul 20:150318. doi: 10.1016/j.gene.2026.150318. Online ahead of print.ABSTRACTNeurodegenerative diseases are progressive disorders that involve the loss and dysfunction of neurons. […]
- US real-world biomarker testing differences and treatment choice in advanced ovarian cancer: results of a retrospective study
Future Oncol. 2026 Jul;22(16):1997-2006. doi: 10.1080/14796694.2026.2691252. Epub 2026 Jul 16.ABSTRACTAIMS: Describe trends in real-world BRCA and homologous recombination deficiency (HRD) testing […]
- Beyond the "cold" barrier: Redefining the clinical paradigm of immune checkpoint inhibitor therapy in ovarian cancer
Author Names: Wu, T.,Zhang, P.,Xi, R.,Shen, Y.,Hu, L.,Chang, S.,Wang, G.,Wang, X.,Lu, J. Database Source: Embase Daily Updates Journal Title: […]
- Genetic Basis of Cardiomyopathies Associated with Endocrinopathies: A Comprehensive Review
Author Names: Concistre, A.,Caramazza, C.,D'Abbondanza, M.,Santori, R.,Imperoli, G. Database Source: Embase Daily Updates Journal Title: […]
- Underutilization of syndrome-specific ICD-10 codes for genetic epilepsies: Implications for precision medicine
Author Names: Sinha, M.,Bajaj, S.,Tai, R.A.,Moura Coelho da Silva, E.,Brunger, T.,Taylor, G.,Merket, A.,Cherukara, A.,Montanucci, L.,Fauteux, M.,Clark, J.,Huth, E.A.,Lhatoo, S.D.,Boselmann, […]
- Molecular Mechanisms and Multi-Omics Integration in Heart Failure: From Pathophysiology to Precision Medicine
Author Names: Dell'Ajra, L.,Maida, C.D.,Ferrantelli, S.,Pacinella, G.,Daidone, M.,Bona, M.M.,Scaglione, S.,Malfitano, R.,Tuttolomondo, A.,Norrito, R.,Cassataro, G.,Vassallo, G.A. […]
- Digital Twins in Neurology Care: Evidence, Limitations, and a Path Forward
Author Names: Gazerani, P. Database Source: Embase Daily Updates Journal Title: Journal of Integrative Neuroscience […]
- Cardiac sarcoidosis: new insights beyond the granuloma using spatial proteomics
Author Names: Margulies, K.B.,Peyster, E.G.,Smith, D.,Bittermann, T.,Bravo, P.E. Database Source: Embase Daily Updates Journal Title: […]
- ATM Immunohistochemistry as a Tool to Identify and Classify Somatic ATM Variants in Prostate Cancer
Author Names: Ferreira, R.,Bisson, K.R.,Beharry, A.,Nicholas, C.,Sheffield, B.S.,Iafolla, M.,Bidnur, S. Database Source: Embase Daily Updates […]
- AI in schizophrenia treatment: personalizing therapy and predicting relapses
Psychiatr Pol. 2026 Apr 30;60(2):191-205. doi: 10.12740/PP/203944. Epub 2026 Apr 30.ABSTRACTThe objective of this study is to present the potential of Artificial Intelligence (AI) in the treatment of […]
Applicabilité
- Bridging Randomized Trial Efficacy and Real-World Effectiveness in Multiple Myeloma: Integrating Clinical Trials and Real-World Evidence for Individualized Care
Author Names: Martino, E.A.,Vigna, E.,Bruzzese, A.,Caserta, S.,Lucia, E.,Olivito, V.,Labanca, C.,Mendicino, F.,Alvaro, M.E.,Amodio, N.,D'Arrigo, G.,Tripepi, G.,Morabito, F.,Gentile, M. […]
- Application value of next generation sequencing technology for pathogen detection in patients with pulmonary infection and lung cancer
Am J Cancer Res. 2026 Jun 15;16(6):2367-2376. doi: 10.62347/UDZH4839. eCollection 2026.ABSTRACTThis study aimed to evaluate the clinical value of next-generation sequencing (NGS) in diagnosing […]
- Personalised approach to hypertension treatment: protocol for the HYPERMARKER randomised controlled trial
BMJ Open. 2026 Jul 16;16(7):e117869. doi: 10.1136/bmjopen-2026-117869.ABSTRACTINTRODUCTION: Blood pressure treatment response is variable in individual patients, and the choice of medical therapy is […]
- Genetic predisposition in gynecologic cancers: From knowledge to clinical management
Hell J Nucl Med. 2026 Jan-Apr;29 Suppl:81-83.ABSTRACTGenetic predisposition contributes significantly to the development of specific gynecologic cancers, particularly ovarian and endometrial […]
- Optimizing Treatment Strategies in the Bipolar Disorder Spectrum With Classical AI Approaches: Systematic Review of Performance, Bias, and Clinical Applicability
JMIR Ment Health. 2026 Jul 21;13:e93307. doi: 10.2196/93307.ABSTRACTBACKGROUND: Bipolar disorder (BD) is a complex and heterogeneous psychiatric condition, characterized by fluctuating clinical […]
- Opportunities and Challenges in Translating Genomics into Population Health Impact: Lessons from Familial Hypercholesterolemia
Public Health Genomics. 2026 Jul 21:1-13. doi: 10.1159/000553208. Online ahead of print.ABSTRACTFamilial hypercholesterolemia (FH) is a common, autosomal dominant genetic disorder characterized by […]
- Clinical and research applications of fibroblast activation protein-alpha inhibitor tracers: a review
Author Names: Desaulniers, M.,Rousseau, E.,Pabst, K.M. Database Source: Embase Daily Updates Journal Title: British Journal of Radiology […]
- Preclinical Safety Evaluation and First-in-Human Translational Study of [177Lu]Lu-TEFAPI-06: An Albumin-Binding Fibroblast Activation Protein Inhibitor for Theranostics
Author Names: Tian, X.,Wang, L.,He, C.,Teng, Y.,Zhang, Y.,Cui, Z.,Liu, J. Database Source: Embase Daily Updates Journal Title: Molecular […]
- Clinical actionability of molecular testing in advanced thyroid cancer: a real-world cohort study
Author Names: Changoer, P.,van Houten, P.,Ceruti, D.,Jaeger, M.,van Engen-van Grunsven, I.,Walraven, J.E.W.,Ottevanger, P.B.,Netea-Maier, R.T. Database Source: Embase […]
- Nectin-4-Targeted Radiotheranostics for Personalized Cancer Therapy: A Systematic Review
Author Names: Schafer, L.,Altunay, B.,Morgenroth, A.,Vogg, A.,Derks, Y.,Pena, Q.,Lammers, T.,Lutje, S.,Mottaghy, F.M. Database Source: Embase Daily Updates […]
Publications CRCHUM
- Impact of direct from clinical sample sequencing assays for infectious diseases diagnostics: A single-centre retrospective cohort study
J Assoc Med Microbiol Infect Dis Can. 2026 May 11;11(2):141-154. doi: 10.3138/jammi-2025-0033. eCollection 2026 Jun.ABSTRACTBACKGROUND: The analytical performance of bacterial targeted sequencing […]
- Geographical, institutional and workplace variability in genetic evaluation, screening practices, multidisciplinary care, and lung transplantation management for familial interstitial lung disease
BMC Pulm Med. 2026 Jul 7. doi: 10.1186/s12890-026-04471-0. Online ahead of print.ABSTRACTBACKGROUND: Advances in genetics have improved the understanding of risk factors for interstitial lung […]
- Participant Heterogeneity in the Prostate Cancer Biobank of the NRG: An Obstacle to Broadening the Reach of Precision Oncology
JCO Precis Oncol. 2026 Jul;10(7):e2600158. doi: 10.1200/PO-26-00158. Epub 2026 Jul 8.ABSTRACTPURPOSE: Precision medicine has revolutionized oncology; however, tumor biomarkers are not reflective of […]
Enseignement - Didactique
- Genomic science and the nurse educator's role: Promoting integration from curriculum to clinical practice
Author Names: Lim, A.G.,Laing, B.,Print, C. Database Source: Embase Daily Updates Journal Title: Nurse education today […]
- Metrics Used for the Evaluation of Chatbots Providing Cancer Genetic Risk Assessment and Education: Systematic Review
JMIR AI. 2026 Jul 15;5:e76400. doi: 10.2196/76400.ABSTRACTBACKGROUND: Chatbots have recently emerged as an alternative approach for delivering cancer risk assessment and genetic counseling. […]
- Integrating cases, enhancing interaction, and promoting learning through assessment: teaching reform and practical outcomes of medical genetics under the OBE concept
Yi Chuan. 2026 Jul;48(7):741-750. doi: 10.16288/j.yczz.25-302.ABSTRACTIn the new era, the teaching of Medical Genetics requires medical students to not only master solid knowledge, but also possess […]
- Precision Pedagogy in Anatomy Education: Integrating AI, Narrative Medicine, and Professional Stratification
Clin Anat. 2026 Jul 17. doi: 10.1002/ca.70192. Online ahead of print.ABSTRACTThe aim of this study was to investigate the effects of an AI-Narrative-Stratified (ANS) model and traditional anatomy […]
- Theranostics Education: Educators' Perspective
J Nucl Med Technol. 2026 Jul 21:jnmt.126.272782. doi: 10.2967/jnmt.126.272782. Online ahead of print.ABSTRACTThe rapid expansion of theranostics has increased the stress felt by many nuclear medicine […]
- Open science practices and feedback-based pedagogy in nanomedicine education: a moderated mediation model of glioma treatment competency
BMC Med Educ. 2026 Jul 21. doi: 10.1186/s12909-026-09948-4. Online ahead of print.ABSTRACTBACKGROUND: Nanomedicine education requires interdisciplinary integration that conventional didactic […]
- Gamification in genetics, genomics, and pharmacogenomics education: a bibliometric analysis of research trends, collaboration, and emerging themes (2000-2025)
Front Med (Lausanne). 2026 Jul 7;13:1824779. doi: 10.3389/fmed.2026.1824779. eCollection 2026.ABSTRACTThe rapid expansion of genomics and pharmacogenomics technologies has created an urgent need for […]
- Theranostics and molecular imaging are taking off: current situation, requirements and how to train more physicians to fill the gap. A perspective from three different continents
Author Names: Veit-Haibach, P.,Lam, W.,Wong, R.K.S.,Cook, G.J.R. Database Source: Embase Daily Updates Journal Title: British Journal of […]
- A quantitative exploration of the clinical genetics curricula across genetic counseling training programs in the United States and Canada
J Genet Couns. 2026 Aug;35(4):e70243. doi: 10.1002/jgc4.70243.ABSTRACTGenetic counseling training programs (GCTPs) in the United States and Canada are expected to provide students with a […]
- Development and implementation of a novel clinical teaching model integrating real-world case with patient-specific three-dimensional imaging in urology
BMC Med Educ. 2026 Jul 1. doi: 10.1186/s12909-026-09765-9. Online ahead of print.ABSTRACTBACKGROUND: Urology encompasses a diverse array of pathologies with complex clinical presentations, demanding […]
- Scoping review and recommendations for development and delivery of education resources for reproductive genetic carrier screening
Eur J Hum Genet. 2026 Jun 30. doi: 10.1038/s41431-026-02152-4. Online ahead of print.ABSTRACTReproductive genetic carrier screening (RGCS) is increasingly available and publicly funded in some […]
Actualité - Formation
- Quebec’s Genomic Medicine Policy will advance precision medicine | McGill University Health Centre
For years, scientists and clinicians at the McGill University Health Centre (MUHC) have worked to advance precision medicine through discoveries in genomics, the study of the complete set of […]
- Implementation of Cat-VRS in AnyVar and AnyVLM
The GA4GH Categorical Representation Specification (Cat-VRS) provides a formal data model and related tools to represent categorical variants. In this presentation, Jennifer Bowser (Nationwide […]
- Génome Québec obtient 30 millions, mais devra réduire ses programmes de recherche
Québec annonce vendredi une enveloppe de plus de 30 millions pour que Génome Québec poursuive ses activités de recherche et d’innovation. C’est toutefois la moitié du montant qu’espérait […]
- La Coalition Priorité Cancer salue l'adoption de la Politique québécoise en médecine génomique : un levier concret pour transformer les soins - PR Newswire Canada
La Coalition Priorité Cancer salue l'adoption de la Politique québécoise en médecine génomique : un levier concret pour transformer les soins PR Newswire Canada
- Génome Canada nomme de nouveaux membres du conseil d’administration et la présidente du CCSI
Génome Canada a le plaisir d’annoncer la nomination de quatre nouveaux membres au conseil d’administration. Ces personnes apportent une expertise qui reflète la croissance continue et […]
- International Consortium on Newborn Sequencing (ICoNS) — ICoNS
Boston, MA • Oct 7- 8, 2026 Meet a few of this year’s presenters The Joseph B. Martin Conference Center at Harvard Medical School* was built […]
- Summary - Got Data? Evaluating Real-World Data Suitability to Inform Regulatory Decision-Making
- GA4GH Product in Action: Individual-Centric Genomics Platform JPN
The GA4GH Implementation Forum’s (GIF) Products in Action series showcases real-world implementations of GA4GH standards or policy frameworks. In this Product in Action blog post, Senkei Umehara of […]
- Québec lance une politique en médecine génomique: un progrès pour des maladies rares - L’actualité
Québec lance une politique en médecine génomique: un progrès pour des maladies rares L’actualité
- D2R lance d’importants projets internationaux pour faire progresser la médecine génomique personnalisée - McGill University
D2R lance d’importants projets internationaux pour faire progresser la médecine génomique personnalisée McGill University
- Mayo Clinic uses Biodesign to teach innovation as a clinical skill
Participants working on medical innovations during the Biodesign Innovation Workshop. New educational programs are helping clinicians and trainees turn everyday healthcare challenges into […]
- Carbon ion therapy: A new era in precision cancer care
This episode of "Tomorrow's Cure" focuses on our growing abilities to treat tumors using technology at the crossroads of biology and physics. Adam Holtzman, M.D. is a radiation oncologist at Mayo […]
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