Description
Innovations - Découvertes
Mais aussi des synthèses, des études et des recherches.
- Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies
Author Names: Koodamvetty A.,Thangavel S. Database Source: Embase Weekly Updates Journal Title: Advanced science (Weinheim, […]
- Mapping breast cancer therapy with circulating tumor cells: The expert perspective
Author Names: Gerratana L.,Gianni C.,Nicolo E.,Pontolillo L.,Bidard F.-C.,Reduzzi C.,Cristofanilli M. Database Source: Embase Weekly Updates […]
- Advancing translational exposomics: bridging genome, exposome and personalized medicine
Hum Genomics. 2025 Apr 30;19(1):48. doi: 10.1186/s40246-025-00761-6.ABSTRACTUnderstanding the interplay between genetic predisposition and environmental and lifestyle exposures is essential for […]
- Integrating Precision Medicine in Diabetes Mellitus: Enhancing Wound Healing and Shaping Future Therapies
Author Names: Kumar A.,Mazumder A.,Bansal P.,Tyagi P.K.,Kaur A. Database Source: Embase Daily Updates Journal Title: Recent Advances in […]
- The Role of Virtual Reality in Personalized Medicine: Advancing Prediction, Prevention, and Participation
J Med Syst. 2025 Apr 29;49(1):56. doi: 10.1007/s10916-025-02191-2.ABSTRACTThe integration of virtual reality (VR) technology into medicine represents a transformative step toward the realization of […]
- Precision Prevention through Social Media: Report of Four Cases
Author Names: Gabarron E.,Lopez-Campos G.,Davies S.,Chomutare T.,Tan I.T.I.,Petersen C. Database Source: Embase Daily Updates Journal Title: […]
- Ethics of Personalised Medicine: Importance of the Multidisciplinary Approach in KidneySign Project
Author Names: Azema D.,Duranton F.,Argiles A.,Rial-Sebbag E. Database Source: Embase Weekly Updates Journal Title: Proteomics […]
- The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing
Nucleic Acids Res. 2025 Apr 22;53(8):gkaf346. doi: 10.1093/nar/gkaf346.ABSTRACTDeveloping customized gene-targeting therapies for the millions of individuals affected by ultra-rare diseases globally […]
- Leveraging the All of Us Database for Primary Care Research with Large Datasets
Author Names: Parente D.J. Database Source: Embase Daily Updates Journal Title: Journal of the American Board of Family Medicine […]
- Intelligent Care: A Scientometric Analysis of Artificial Intelligence in Precision Medicine
Med Sci (Basel). 2025 Apr 19;13(2):44. doi: 10.3390/medsci13020044.ABSTRACTThe integration of advanced computational methods into precision medicine represents a transformative advancement in […]
- Precision Reimagined: CRISPR and Multiomics Transform Systemic Lupus Erythematosus Diagnosis and Therapy
Int J Rheum Dis. 2025 Apr;28(4):e70189. doi: 10.1111/1756-185X.70189.ABSTRACTSystemic lupus erythematosus (SLE) is a complex autoimmune disorder with diverse clinical manifestations and unpredictable […]
Axes CHUM
Cet onglet concerne exclusivement les quatre axes qui suivent : oncologie, neurosciences, cardiovasculaire et imagerie.
- Predictive cardio-omics: translating single-cell multiomics into tools for personalized medicine
Author Names: Pekayvaz K.,Heinig M.,Stark K. Database Source: Embase Weekly Updates Journal Title: Nature Reviews Cardiology […]
- Deep learning in nuclear medicine: from imaging to therapy
Author Names: Zhang M.-X.,Liu P.-F.,Zhang M.-D.,Su P.-G.,Shang H.-S.,Zhu J.-T.,Wang D.-Y.,Ji X.-Y.,Liao Q.-M. Database Source: Embase Weekly Updates […]
- Precision Medicine in Parkinson's Disease
Author Names: Maayan Eshed G.,Alcalay R.N. Database Source: Embase Weekly Updates Journal Title: Neurologic Clinics […]
- Imaging and management of lymphedema in the era of precision oncology
Author Names: Rai P.,Mahajan A.,Shukla S.,Pokar N. Database Source: Embase Daily Updates Journal Title: British Journal of Radiology […]
- Biomarkers and Treatment Selection for Depression - A Precision Medicine Approach
Author Names: Trivedi M.H. Database Source: Embase Daily Updates Journal Title: Indian Journal of Psychiatry Article […]
- Session Introduction: Translating Big Data Imaging Genomics Findings to the Individual: Prediction of Risks and Outcomes in Neuropsychiatric Illnesses
Pac Symp Biocomput. 2025;30:594-598. doi: 10.1142/9789819807024_0042.ABSTRACTThis PSB 2025 session is focused on opportunities, challenges and solutions for translating Big Data Imaging Genomic […]
- Emerging therapeutic strategies in glioblastsoma: drug repurposing, mechanisms of resistance, precision medicine, and technological innovations
Author Names: Anwer M.S.,Abdel-Rasol M.A.,El-Sayed W.M. Database Source: Embase Daily Updates Journal Title: Clinical and Experimental […]
- Toward Timely and Equitable Advanced Biomarker Testing for Patients with Metastatic Cancer in Canada
Author Names: Sheffield B.S.,Banerji S.,Chankowsky A.,Dudani S.,Gill S.,Gorski Z.,Kassam S.,Macaulay C.,Manna M.,Perdrizet K.,Ramjeesingh R.,D'Angelo M.S.,Servidio-Italiano F. […]
- The Cost Effectiveness of Genomic Medicine in Cancer Control: A Systematic Literature Review
Author Names: Bourke M.,McInerney-Leo A.,Steinberg J.,Boughtwood T.,Milch V.,Ross A.L.,Ambrosino E.,Dalziel K.,Franchini F.,Huang L.,Peters R.,Gonzalez F.S.,Goranitis I. […]
- A decalogue of Molecular Tumor Board (MTB) recommendations from the CAN.HEAL Consortium
Author Names: Ciliberto G.,De Maria R.,Giacomini P.,Trapani V.,Betti M.,Bucci G.,Buglioni S.,D'Auria L.,De Angelis R.,De Nicolo A.,Dupain C.,Frederickx N.,Genuardi M.,Indraccolo S.,Kolanowska […]
- Cardiomyopathy genetic testing: insights into demographics, counseling, and cascade screening
Author Names: Bui Q.M.,Silver E.,Argiro A.,Murray S.,Korty L.,Silva Enciso J.,Urey M.A.,Chi N.C.,Hong K.N.,Adler E.D. Database Source: Embase Daily Updates […]
- Emerging artificial intelligence-driven precision therapies in tumor drug resistance: recent advances, opportunities, and challenges
Mol Cancer. 2025 Apr 23;24(1):123. doi: 10.1186/s12943-025-02321-x.ABSTRACTDrug resistance is one of the main reasons for cancer treatment failure, leading to a rapid recurrence/disease progression […]
- Coronary microcirculation in myocardial ischemia: A genetic perspective
J Mol Cell Cardiol. 2025 Apr 10:S0022-2828(25)00060-4. doi: 10.1016/j.yjmcc.2025.04.002. Online ahead of print.ABSTRACTCoronary microvascular dysfunction (CMD) is a major contributor to ischemic […]
Applications cliniques
- A guide to utilizing implementation science for genetic counseling
J Genet Couns. 2025 Jun;34(3):e70039. doi: 10.1002/jgc4.70039.ABSTRACTImplementation Science (IS) is a growing field that provides tools to understand and facilitate the uptake of research and […]
- Clinical implications of miR-195 in cancer: mechanisms, potential applications, and therapeutic strategies
Author Names: Xu S.,He L.,Chen Y.,Lin T.,Tang L.,Wu Y.,He Y.,Sun X. Database Source: Embase Daily Updates Journal Title: Journal of Cancer […]
- Unravelling disease complexity: integrative analysis of multi-omic data in clinical research
Expert Rev Proteomics. 2025 Apr;22(4):149-162. doi: 10.1080/14789450.2025.2491357. Epub 2025 Apr 13.ABSTRACTINTRODUCTION: A holistic view on biological systems is today a reality with the application […]
- Genetic variants in NUDT15 gene their clinical implications in cancer therapy
Author Names: Jarrar Y.,Ghishan M.,Khirfan F.,Hakooz N. Database Source: Embase Daily Updates Journal Title: Drug Metabolism and Personalized […]
- Pharmacogenomic Testing in the Clinical Laboratory: Historical Progress and Future Opportunities
Author Names: Moyer A.M.,Black J.L. Database Source: Embase Daily Updates Journal Title: Annals of laboratory medicine […]
- Efficient and scalable construction of clinical variable networks for complex diseases with RAMEN
Author Names: Xiong Y.,Wang J.,Shang X.,Chen T.,Fraser D.D.,Fonseca G.J.,Rousseau S.,Ding J. Database Source: Embase Daily Updates Journal Title: […]
- Pharmacogenomic analysis and clinical annotation of 635 patients
Author Names: Bagci O.,Sanliturk B.,Ozdemir E.M.,Kocak N.,Cora T. Database Source: Embase Daily Updates Journal Title: Personalized Medicine […]
- Clinical translation of microbiome research
Nat Med. 2025 Apr;31(4):1099-1113. doi: 10.1038/s41591-025-03615-9. Epub 2025 Apr 11.ABSTRACTThe landscape of clinical microbiome research has dramatically evolved over the past decade. By leveraging […]
Publications CRCHUM
- Whole genome sequencing of M. tuberculosis for disease control in high-burden settings: study protocol for a cluster randomized controlled trial evaluating different community-wide intervention strategies in rural Madagascar
Trials. 2024 Oct 25;25(1):717. doi: 10.1186/s13063-024-08537-4.ABSTRACTBACKGROUND: Retrospective and descriptive molecular epidemiology studies have shown that Mycobacterium tuberculosis whole genome […]
- Conference Report: Review of Clinical Implementation of Advanced Quantitative Imaging Techniques for Personalized Radiotherapy
Tomography. 2024 Nov 14;10(11):1798-1813. doi: 10.3390/tomography10110132.ABSTRACTThe topic of quantitative imaging in radiation therapy was presented as a "Masterclass" at the 2023 annual meeting of […]
- A comprehensive human embryo reference tool using single-cell RNA-sequencing data
Nat Methods. 2025 Jan;22(1):193-206. doi: 10.1038/s41592-024-02493-2. Epub 2024 Nov 14.ABSTRACTStem cell-based embryo models offer unprecedented experimental tools for studying early human […]
- Genetics of Hypertension: Additive and Interactive Effects
Hypertension. 2025 Jan;82(1):3-7. doi: 10.1161/HYPERTENSIONAHA.124.21724. Epub 2024 Nov 11.NO ABSTRACTPMID:39523998 | DOI:10.1161/HYPERTENSIONAHA.124.21724
- Towards a New Integrated Model for Taking Into Account the Experiential Knowledge of People With Chronic Diseases, Integrating Mediation, Therapeutic Education and Partnership: The Expanded Chronic Care Patient-Professional Partnership Model
Health Expect. 2024 Oct;27(5):e70054. doi: 10.1111/hex.70054.ABSTRACTINTRODUCTION: The Chronic Care Model (CCM), the Expanded Chronic Care Model (ECCM) and the eHealth Enhanced Chronic Care Model […]
- Body mass index modifies genetic susceptibility to high systolic blood pressure in adolescents and young adults: results from an 18-year longitudinal study
J Hum Hypertens. 2025 Mar 15. doi: 10.1038/s41371-025-01003-x. Online ahead of print.ABSTRACTGenome-wide association studies (GWAS) in adults have identified single nucleotide polymorphisms (SNPs) […]
- Genetic characterization of a rare case of pheochromocytoma in a pulmonary transplant patient
Front Endocrinol (Lausanne). 2025 Feb 6;15:1481906. doi: 10.3389/fendo.2024.1481906. eCollection 2024.ABSTRACTBACKGROUND: Pheochromocytomas (PCCs) and paragangliomas (PGLs) (PPGLs) are rare tumours […]
- Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology
Sci Rep. 2025 Feb 12;15(1):5305. doi: 10.1038/s41598-025-88985-3.ABSTRACTAdolescent Idiopathic Scoliosis (AIS) is the most common orthopedic condition requiring surgery, affecting 4% of adolescents. […]
- Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey
BMC Pulm Med. 2025 Feb 3;25(1):59. doi: 10.1186/s12890-025-03532-0.ABSTRACTBACKGROUND: Advances in the field of genetics of interstitial lung diseases (ILDs) have led to the recent consensus […]
- Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data
Nat Methods. 2025 Mar;22(3):636. doi: 10.1038/s41592-025-02601-w.NO ABSTRACTPMID:39856235 | PMC:PMC11903301 | DOI:10.1038/s41592-025-02601-w
- Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity
Front Immunol. 2025 Jan 6;15:1505752. doi: 10.3389/fimmu.2024.1505752. eCollection 2024.ABSTRACTBACKGROUND: Factors leading to severe COVID-19 remain partially known. New biomarkers predicting […]
- Leveraging hierarchical structures for genetic block interaction studies using the hierarchical transformer
medRxiv [Preprint]. 2025 Feb 14:2024.11.18.24317486. doi: 10.1101/2024.11.18.24317486.ABSTRACTInitially introduced in 1909 by William Bateson, classic epistasis (genetic variant interaction) refers […]
- Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling
Nat Methods. 2025 Apr 11. doi: 10.1038/s41592-025-02648-9. Online ahead of print.ABSTRACTDifferentiating sequencing errors from true variants is a central genomics challenge, calling for error […]
- Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors
Gut Pathog. 2025 Apr 11;17(1):21. doi: 10.1186/s13099-025-00694-4.ABSTRACTBACKGROUND: The gut microbiome represents a novel biomarker for melanoma and non-small cell lung cancer (NSCLC) patients […]
- Evidence-based personalised medicine in critical care: a framework for quantifying and applying individualised treatment effects in patients who are critically ill
Lancet Respir Med. 2025 Apr 15:S2213-2600(25)00054-2. doi: 10.1016/S2213-2600(25)00054-2. Online ahead of print.ABSTRACTClinicians aim to provide treatments that will result in the best outcome for […]
Enseignement - Didactique
- Identifying potential genetic counseling program applicant competencies
J Genet Couns. 2025 Jun;34(3):e70020. doi: 10.1002/jgc4.70020.ABSTRACTGenetic counseling (GC) program admission is highly competitive. Developing applicant competencies, like the Association of […]
- Examining a career exploration workshop's influence on engagement in and accessibility to the genetic counseling profession
J Genet Couns. 2025 Jun;34(3):e70001. doi: 10.1002/jgc4.70001.ABSTRACTProspective genetic counseling students face many barriers when seeking to engage with the genetic counseling (GC) profession and […]
- Resident clinical dashboards to support precision education in emergency medicine
AEM Educ Train. 2025 Apr 29;9(Suppl 1):S29-S39. doi: 10.1002/aet2.70020. eCollection 2025 Apr.ABSTRACTINTRODUCTION: With the move toward competency-based medical education (CBME), data from the […]
- Reconciling Competencies in Undergraduate Medical Genetics Education: APHMG versus PCME Competencies
Genet Med. 2025 Apr 25:101448. doi: 10.1016/j.gim.2025.101448. Online ahead of print.ABSTRACTPURPOSE: We wanted to understand whether there were gaps within and/or between the Association of […]
- Longitudinal curriculum design shows promise to improve pharmacogenomics education in an observational study
Curr Pharm Teach Learn. 2025 Apr 23;17(7):102359. doi: 10.1016/j.cptl.2025.102359. Online ahead of print.ABSTRACTINTRODUCTION: Longitudinal curriculum has been suggested for improving […]
- Development of a Pharmacogenomics Case Repository for Pharmacy Educators
Am J Pharm Educ. 2025 Apr 1:101397. doi: 10.1016/j.ajpe.2025.101397. Online ahead of print.ABSTRACTOBJECTIVE: To describe the creation of a curated, shared repository of pharmacogenomics cases for […]
- Exploring the research hotspots and trends in genetic education reform
Yi Chuan. 2025 Apr;47(4):399-408. doi: 10.16288/j.yczz.24-292.ABSTRACTGenetics, as a core discipline of life sciences, has broad applications in medicine, agriculture, and environmental protection. […]
- An interprofessional education program based on the ARCS-V motivation model on the theme of "Chronic Disease Management and Patient Safety": action research
BMC Med Educ. 2025 Apr 14;25(1):532. doi: 10.1186/s12909-025-07085-y.ABSTRACTAIM: The aim of the study was to develop and implement an interprofessional education (IPE) program that would enhance […]
- Quality education as a cornerstone of community genetics
J Community Genet. 2025 Apr 17. doi: 10.1007/s12687-025-00794-3. Online ahead of print.NO ABSTRACTPMID:40244505 | DOI:10.1007/s12687-025-00794-3
- Empowering human research ethics committees to review genomics applications: evaluating the utility of a custom online education resource
Eur J Hum Genet. 2025 Apr 17. doi: 10.1038/s41431-025-01846-5. Online ahead of print.ABSTRACTComplex genomic technologies are increasingly utilised in research. However, human research ethics […]
Actualité - Formation
- L’utilisation de 100 000 génomes nous aidera à repenser les soins de santé au Canada
Et si votre médecin pouvait vraiment vous voir? Pas seulement sur le plan physique, mais aussi sur le plan génétique. Les variations génétiques causent des […]
- New awards aim to make Minnesota a leader in regenerative medicine
Regenerative Medicine Minnesota has awarded funding to three projects aimed at strengthening Minnesota's capabilities for developing and delivering therapies that replace, restore, rejuvenate or […]
- Critical lung cancer staging streamlined by AI in FACIT Falcons’ Fortunes winning tech - Ontario Institute for Cancer Research
Dr. Waël Hanna of NodeAI Diagnostics took home the $100,000 Ernsting Entrepreneurship Award for his innovative technology to improve lymph node biopsies. Knowing whether lung cancer has spread to […]
- ESHG Conference 2025
ESHG Conference 2025Doris Wimmer2025-04-01T15:42:46+02:00
- IHU PRISM, a precision medicine institute (France), interview with Dr. Maud Kamal
22 April 2025 – Dr. Maud Kamal, introduced the IHU PRISM, the first National Centre for Precision Medicine in oncology in France launched in 2020 and labelled « Institut Hospitalo-Universitaire » […]
- A golden era for personalized medicine is approaching, but are we ready? - The Conversation
A golden era for personalized medicine is approaching, but are we ready? The Conversation
- GA4GH 13th Plenary registration is now open!
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