Description
Innovations - Découvertes
Mais aussi des synthèses, des études, des réflexions et des recherches.
- The Role of Muscle Biopsy in the Era of Modern Genomic Medicine-A Review
Author Names: Sadeh, M.,Dabby, R. Database Source: Embase Daily Updates Journal Title: Journal of Clinical Medicine […]
- Artificial Intelligence in Cardiovascular Ultrasound: Clinical Applications, Foundation Models, and the Path to Precision Cardiology
Author Names: Tupu, A.E.,Tudor, S.S.,Dumitru, C.N.,Stefan, C.S.,Fertu, I.D. Database Source: Embase Daily Updates Journal Title: Journal of […]
- Emerging Trends in Smart Wearable Technologies Across Medical and Lifestyle Domains: Implications for Personalized Healthcare
Author Names: Pandit, P.R.,Sreedhar, D.,Muragundi, P.M.,Goyal, A.K.,Mahadeva, R.,Shwetha, T.S. Database Source: Embase Weekly Updates Journal […]
- A systematic scoping review of the molecular pathogenesis of digestive system cancers (2013-2025)
Author Names: Voon, P.J.,Subramaniam, S.,Lai, W.H.,Razali, F.,Tiong, L.L.,Tan, S.H.,Sim, E.U.-H. Database Source: Embase Daily Updates Journal […]
- Aggregation-Induced Emission Luminogens: Emerging Theranostic Platforms for Pulmonary Diseases
Author Names: Hou, Y.,Wang, D. Database Source: Embase Daily Updates Journal Title: Luminescence Article Title: […]
- Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making
Author Names: Caruso, A.,Delvecchio, A.,Memeo, R.,Lanzino, M.,Martinotti, S. Database Source: Embase Daily Updates Journal Title: Frontiers […]
- Global genomic surveillance uncovers emergence and spatiotemporal patterns of World Health Organization priority antibiotic resistance in invasive Salmonella
Nat Commun. 2026 Aug 18;17(1):9871. doi: 10.1038/s41467-026-76354-1.ABSTRACTAntimicrobial resistance (AMR) in invasive Salmonella infections remains a global public health concern, and enhanced […]
- Current Practices for Evaluating Clinical Supervisors in North American Genetic Counseling Programs
J Genet Couns. 2026 Aug;35(4):e70280. doi: 10.1002/jgc4.70280.ABSTRACTClinical supervision is a cornerstone of genetic counseling education, yet there are no standardized methods for evaluating […]
- Translating evidence into practice: Developing Canada's first position statement on genomics-informed oncology nursing
Can Oncol Nurs J. 2026 Jan 1;36(1):66-72. doi: 10.5737/2368807636166. eCollection 2026.ABSTRACTThe integration of genomics in oncology care is accelerating in Canada, presenting new opportunities for […]
Axes CHUM
Cet onglet concerne exclusivement les quatre axes qui suivent : oncologie, neurosciences, cardiovasculaire, imagerie et pré-greffe rénale.
- Pangenomes aid accurate detection of large insertions and deletions from targeted sequencing: the case of cardiomyopathies
Genome Med. 2026 Aug 26;18(1):132. doi: 10.1186/s13073-026-01749-0.ABSTRACTBACKGROUND: Gene panels represent a widely used strategy for genetic testing in a vast range of Mendelian disorders. While […]
- PRECISION MEDICINE IN PRACTICE: BALANCING GENES AND JUDGMENT IN LATE-LIFE BIPOLAR DISORDER
Author Names: Pham, K. Database Source: Embase Daily Updates Journal Title: American Journal of Geriatric Psychiatry […]
- The roles of chromatin remodeling and 3D genome organization in cancers: from mechanistic insights to emerging treatment options
Mol Cancer. 2026 Aug 7;25(1):218. doi: 10.1186/s12943-026-02763-x.ABSTRACTChromatin remodeling comprises a set of molecular mechanisms that regulate gene transcription, DNA replication, and DNA […]
- The genetic overlap between schizophrenia and major depression with cognitive function
Mol Psychiatry. 2026 Sep 16. doi: 10.1038/s41380-026-03887-8. Online ahead of print.ABSTRACTThis study aimed to systematically dissect the shared genetic basis of schizophrenia (SCZ) and major […]
- The emerging trends in prostate cancer treatment: a systematic review of the literature
Author Names: Fatima, S.A.,Haider, K.H.,Qutubuddin, S.,Begum, Y.,Stevenson, M.,Fatima, K.,Anwar, E.I.,Barg, M. Database Source: Embase Daily Updates […]
- Therapeutic Challenges and Future Breakthroughs in Amyotrophic Lateral Sclerosis: From Precision Medicine to Innovative Trial Design
Drug Des Devel Ther. 2026 Aug 22;20:626069. doi: 10.2147/DDDT.S626069. eCollection 2026.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a highly heterogeneous and fatal neurodegenerative disorder, for […]
- Pharmacogenomics and artificial intelligence in cardiovascular disease: emerging tools for precision medicine
Pharmacogenomics. 2026 Sep 14:1-13. doi: 10.1080/14622416.2026.2732154. Online ahead of print.ABSTRACTCardiovascular diseases (CVD) remain a predominant cause of mortality and morbidity globally. […]
- Epilepsy: Bridging Epidemiological Landscapes, Molecular Mechanisms, and Emerging Precision Therapeutics
Neuropsychiatr Dis Treat. 2026 Sep 11;22:629134. doi: 10.2147/NDT.S629134. eCollection 2026.ABSTRACTEpilepsy ranks among the most prevalent neurological disorders worldwide, and recent years have […]
- From genetic testing to prevention: an integrated clinical pathway for hereditary risk assessment in tubo-ovarian cancer
Int J Gynecol Cancer. 2026 Aug 3;36(9):104898. doi: 10.1016/j.ijgc.2026.104898. Online ahead of print.ABSTRACTHereditary tubo-ovarian cancer risk assessment has evolved from a BRCA1/2-centered […]
- Population Genomic Screening for Hereditary Cancer Risk: Patient Experience, Perceptions, and Downstream Clinical Outcomes
J Genet Couns. 2026 Aug;35(4):e70274. doi: 10.1002/jgc4.70274.ABSTRACTPopulation-wide genomic screening (PWGS) offers a novel approach to identifying individuals at risk for hereditary cancer […]
- Single-section multiplex spatial proteomics of immune microenvironments in kidney transplantation
Front Immunol. 2026 Aug 24;17:1861589. doi: 10.3389/fimmu.2026.1861589. eCollection 2026.ABSTRACTCharacterizing kidney disease is challenged by marked cellular heterogeneity and limited tissue […]
- Two Genomes, one Outcome: Stratifying Donor and Recipient Polygenic Risk Score to Improve Kidney Allograft Longevity
Transplantation. 2026 Sep 10. doi: 10.1097/TP.0000000000005908. Online ahead of print.ABSTRACTKidney transplantation outcomes arise from complex interactions among donor organ quality, recipient […]
- Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review
Author Names: Wang, Y.,Yeoh, S.Y.,Tuffaha, H.,Wood, J.L.,Thurecht, K.J. Database Source: Embase Daily Updates Journal Title: Journal of […]
Applicabilité
- Clinical Utility of Targeted Third-Generation Sequencing for Pathogen Detection in Community-Acquired Pneumonia: A Real-World Comparative Study of China
J Infect Dev Ctries. 2026 Aug 31;20(8):1122-1132. doi: 10.3855/jidc.22870.ABSTRACTOBJECTIVE: To evaluate the diagnostic performance and clinical utility of targeted third-generation sequencing (tTGS) […]
- Nanomaterial-based drug delivery systems: From intelligent delivery to clinical translation and precision nanomedicine
Biomed Pharmacother. 2026 Aug 27;203:119888. doi: 10.1016/j.biopha.2026.119888. Online ahead of print.ABSTRACTNanomaterial-based drug delivery systems (NDDS) have become enabling technologies for […]
- Precision nanomedicine for pulmonary diseases: from molecular targeting to clinical translation
Signal Transduct Target Ther. 2026 Sep 1;11(1):358. doi: 10.1038/s41392-026-02982-0.ABSTRACTThe pulmonary system is a vital interface between the body and the external environment, making it highly […]
- Clinical utility of targeted next-generation sequencing for rapid detection, species differentiation, drug resistance profiling, and prognostic evaluation in Mycobacterium tuberculosis: a multi-center retrospective cohort study
Front Cell Infect Microbiol. 2026 Aug 18;16:1818202. doi: 10.3389/fcimb.2026.1818202. eCollection 2026.ABSTRACTBACKGROUND: Tuberculosis (TB) remains a global health threat, which is complicated by […]
- Artificial Intelligence Across the Cancer Theranostics Workflow: Critical Appraisal of Current Evidence and Future Clinical Translation
Mol Imaging Biol. 2026 Sep 11. doi: 10.1007/s11307-026-02136-2. Online ahead of print.ABSTRACTArtificial intelligence (AI) is transforming cancer management and theranostics by improving the […]
- The Translational Paradox of Cancer Nanomedicine: Biological, Pharmacokinetic, and Manufacturing Barriers to Clinical Success
Biology (Basel). 2026 Sep 4;15(17):1550. doi: 10.3390/biology15171550.ABSTRACTCancer nanomedicine has generated extensive preclinical evidence of improved drug delivery, pharmacokinetics, and […]
- Metagenomic sequencing in encephalitis diagnostics: Challenges and opportunities in clinical settings
PLoS One. 2026 Sep 15;21(9):e0358189. doi: 10.1371/journal.pone.0358189. eCollection 2026.ABSTRACTThe primary aim of this study was to determine whether metagenomic next-generation sequencing (mNGS) […]
- siRNA and mRNA Therapeutics: A Comprehensive Review of Mechanisms, Delivery Strategies, Clinical Applications, and Future Directions in Precision Pharmacology
Curr Gene Ther. 2026 Sep 10. doi: 10.2174/0115665232434772251211065217. Online ahead of print.ABSTRACTSmall interfering RNA (siRNA) and messenger RNA (mRNA) therapeutics represent transformative […]
- Clinical Utility of a Type 1 Diabetes Genetic Risk Score Measured as Part of MODY Genetic Testing
Diabetes Care. 2026 Aug 18:dc261081. doi: 10.2337/dc26-1081. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate the clinical utility of incorporating a type 1 diabetes genetic risk score (T1DGRS) […]
- Unlocking the Circulating Proteome: Toward Clinical Translation
J Proteome Res. 2026 Sep 4;25(9):4367-4379. doi: 10.1021/acs.jproteome.6c00277.ABSTRACTBlood-based proteomics is approaching a translational inflection point. Driven by advances in measurement […]
- Nanomedicine in Lung Transplantation: Emerging Solutions for Clinical Challenges
Am J Transplant. 2026 Sep 15:S1600-6135(26)02756-5. doi: 10.1016/j.ajt.2026.09.013. Online ahead of print.ABSTRACTLung transplantation (LT) remains the definitive treatment for select patients with […]
Publications CRCHUM
- Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
Cancer Treat Rev. 2026 Jul 16;149:103190. doi: 10.1016/j.ctrv.2026.103190. Online ahead of print.ABSTRACTPatient-derived xenografts (PDX) and patient-derived organoids (PDO) are widely used to model […]
- TRACR: an anterograde transneuronal tracing system for genetic access across synapses and longitudinal circuit analysis
bioRxiv [Preprint]. 2026 Jul 12:2026.02.08.704659. doi: 10.64898/2026.02.08.704659.ABSTRACTFollowing neural signals as they converge onto and diverge from individual neurons is central to […]
- Patient-Derived 3D Heart-On-a-Chip Model of Dilated Cardiomyopathy With Embedded Bead-Based Mapping of Tissue Contractility
Adv Healthc Mater. 2026 Jul 25:e71464. doi: 10.1002/adhm.71464. Online ahead of print.ABSTRACTDilated cardiomyopathy (DCM) is the leading cause of heart transplantation, with a 50% risk of […]
Enseignement - Didactique
- Identifying General Practitioners, Nurses, and Pharmacists Training Needs in Precision Medicine: A Survey Study
J Contin Educ Health Prof. 2026 Sep 15. doi: 10.1097/CEH.0000000000000677. Online ahead of print.ABSTRACTINTRODUCTION: The clinical advances of precision medicine, elevating clinical decision-making […]
- Preparing Genetic Counselors for Advocacy Partnerships: A Novel Internship Model
J Genet Couns. 2026 Oct;35(5):e70289. doi: 10.1002/jgc4.70289.ABSTRACTPatient advocacy organizations (PAOs) and genetic counseling have expanded in tandem with the growth of precision medicine. […]
- A case study of patient and public involvement in sepsis genomics research
Res Involv Engagem. 2026 Sep 15;12(1):146. doi: 10.1186/s40900-026-00962-w.ABSTRACTBACKGROUND: Patient and public involvement (PPI) in research has been shown to be integral to good research […]
- Building a genomics-capable cancer workforce: a competency-based framework for education and training in precision oncology
EClinicalMedicine. 2026 Aug 10;99:104142. doi: 10.1016/j.eclinm.2026.104142. eCollection 2026 Sep.ABSTRACTBACKGROUND: The Lancet Oncology Commission on cancer genomics and precision oncology […]
- International expert perspectives on pharmacogenomics in pharmacy education: a qualitative study with implications for South Africa
Front Pharmacol. 2026 Aug 18;17:1888534. doi: 10.3389/fphar.2026.1888534. eCollection 2026.ABSTRACTINTRODUCTION: Pharmacogenomics (PGx) has the potential to transform healthcare in South Africa […]
- Precision Education: How Ready Are Obstetrics and Gynecology Clerkships for the Future of Medical Education?
J Surg Educ. 2026 Oct;83(10):104119. doi: 10.1016/j.jsurg.2026.104119. Epub 2026 Aug 26.ABSTRACTOBJECTIVES: Precision education has been heralded as the future of medical education, yet substantial […]
- Pilot Evaluation of a Digital Pretest Education Platform for Genomic Counseling: Perspectives of Health Care Providers and Patients
J Genet Couns. 2026 Oct;35(5):e70288. doi: 10.1002/jgc4.70288.ABSTRACTTraditional in-person consultations for genetic services create access barriers. We hypothesized that the Genetics Adviser […]
Actualité - Formation
- Médecine personnalisée: La perspective d'un diagnostic précoce de l'asthme est un soulagement - Swiss government
Médecine personnalisée: La perspective d'un diagnostic précoce de l'asthme est un soulagement Swiss government
- Nouvel ensemble de données de spirométrie CanPath disponible pour les chercheurs - CanPath - Canadian Partnership for Tomorrow’s Health
CanPath est heureux d’annoncer la publication de son ensemble harmonisé de données de spirométrie de base, maintenant disponible pour les chercheurs au Canada et à l’international La […]
- Bulletin de veille stratégique : Analyse pangénomique : tendances émergentes et contextes d'application
Les technologies d’analyses génomiques jouent un rôle essentiel dans le diagnostic des maladies rares et héréditaires, l’identification des prédispositions génétiques et la mise en œuvre […]
- Un nouveau rapport sur le potentiel économique du Canada en génomique - PR Newswire Canada
Un nouveau rapport sur le potentiel économique du Canada en génomique PR Newswire Canada
- Long-term clinical and genomic surveillance of rare respiratory enterovirus C types in France, 2013-2025
J Clin Virol. 2026 Sep 11;186:106001. doi: 10.1016/j.jcv.2026.106001. Online ahead of print.ABSTRACTINTRODUCTION: Rare enterovirus types assigned to species C (EV-C) display respiratory tropism and […]
- Moderna et Merck | Traitement prometteur contre le mélanome: «C'est de la médecine personnalisée - 985fm.ca
Moderna et Merck | Traitement prometteur contre le mélanome: «C'est de la médecine personnalisée 985fm.ca
- Cancer vaccines are finally showing results. Can Canada deliver them? - Canadian Affairs
Cancer vaccines are finally showing results. Can Canada deliver them? Canadian Affairs
- Déployer la médecine génomique - Inserm
Déployer la médecine génomique Inserm
- Can disease be identified before symptoms begin? Mayo Clinic researchers are looking for answers
Mayo Clinic researchers are combining biological, environmental and health data with artificial intelligence to identify changes that may signal disease years before clinical symptoms appear […]
- Researchers identify tumour “fingerprints” linked to aggressive prostate cancer - Ontario Institute for Cancer Research
Exciting new findings from a landmark international collaboration co-led by OICR were published in Nature. Prostate cancer leaves behind genetic “fingerprints” that provide clues about how […]
- New Funding Opportunity: Ethical, Legal and Social Implications (ELSI) of Genomics Catalyst Grants
Researchers at McGill University and D2R partner institutions are invited to apply for the new Ethical, Legal and Social Implications (ELSI) of Genomics Catalyst Grants, a funding opportunity […]
- Mount Sinai launches Center for Genomic AI and Microbiome Medicine to advance precision medicine
image: Gang Fang, PhD, Director of the Center for Genomic AI and Microbiome Medicine and Professor of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, studies how human […]
- Beyond the Human Genome Project: What’s next for genomics?
Dr. Eric Green addresses the audience, August 2026. | Photo: Changping Laboratory The “25 Years of Human Genome” International Symposium was held last month at Changping Laboratory in Beijing, […]
- Mapping cancer’s genetic drivers: Sequencing, biomarkers and equity
Image: © ArtemisDiana | iStock For this Special Report, Lorna Rothery spoke to Dr Priya Hays of Hays Documentation Specialists to find out more about cancer genomics. What are the most significant […]
- Création d'un nouveau centre de recherche en santé pour répondre aux priorités des Autochtones au Yukon
Un investissement de 2,4 millions de dollars appuiera la recherche en santé menée par les Premières Nations sur le territoire, y compris le renforcement des capacités et la formation. […]
- The Complete Diploid Human Genome Has Finally Been Sequenced
Read time: 5 minutes In 2022, the first human genome was completed, filling in the last 8% of the genome left unresolved by the Human Genome Project. Researchers have now gone one step further […]
- Newborn screening for cancer risk could save lives. Should it be done?
Daniel Oakes was 2½ years old when his mother noticed an unusual glow in his eye. When he moved his head, Daniel’s right pupil shone white, like a bleached-out version of the red-eye effect […]
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